An Amazing Aptness for Learning Trades: The Role of Enslaved Craftsmen in Charleston Cabinetmaking Shops

This paper examines the role of enslaved craftsmen in Charleston cabinetmaking shops during the late-eighteenth century and how wealthy Charlestonians’ desire fashionable goods fueled the demand for this labor force. The first chapter examines the rise of the wealthy Charlestonians and the origins of their taste for fashionable goods. The second chapter explores the increased use of enslaved craftsmen in Charleston cabinetmaking shops during the last half of the eighteenth century and how they affected the production of fashionable cabinet goods

Retrospective analysis of the cholesterol levels in a european mid-latitude population between 2007 and 2018: Controversies and therapeutic implications

Background and aim of the work: Coronary heart disease is the leading cause of morbidity and mortality in developed countries and its association with LDL-cholesterol has been well established. During the last decades statin therapy, and an healthy lifestyle, has proven highly effective in reducing cardiovascular event rates. Yet, there is still controversy among national guidelines and clinical practice with regard to LDL-cholesterol measurements. The aim of this study was to verify whether significant changes in cholesterol levels were observed over a relatively long (12 years) period. We also compared the Friedewald-calculated with directly-measured LDL cholesterol in order to verify whether the two methods were equivalent. Meth-ods: We retrospectively analyzed 288000 data (total cholesterol, HDL, LDL both directly-measured and Friedewald-calculated, and triglycerides), from 57600 individuals, collected at the San Raffaele Hospital in Milan between 2007 and 2018. Data were statistically analyzed using a linear regression over the 12 years long period of time. Results: We observed a general decreasing trend in total cholesterol (and an increasing trend in HDL) and a decrease in triglycerides only in the male group. Directly-measured LDL did not cor-relate well with calculated LDL. Conclusion: The total cholesterol decrease and the corresponding increment in HDL was attributed to either an increased use of statin and/or an improvement of the general population dietary habits. The latter was further confirmed by the decrease in triglycerides observed in the male group. Based on our data, an alternative method for assessing atherogenics lipoproteins level has been proposed. (www.actabiomedica.it)

Giving Voice: Pediatric Nurses’ Perception of Workplace Violence

The aim of this study was to examine the lived experience of pediatric nurses who work on inpatient hospital units that are exposed to workplace violence from patients and visitors. Workplace violence directed at nurses is an alarming phenomenon and has been understudied in regard to pediatric nurses who work on inpatient hospital units. Qualitative research was used to describe nurses’ experience with workplace violence by directly examining their perceptions of the problem. An interpretive phenomenological approach of inquiry was used as a strategy for this qualitative study. Twenty-four nurses who work at a Magnet teaching hospital in Upstate New York were the participants. The participants volunteered for the study and semi-structured, face-to-face interviews were conducted and audio-taped. The participants’ narratives were transcribed and analyzed. An inductive inquiry process was used to interpret and structure meanings from the interview data. The narratives were coded for general themes. Validity and trustworthiness was demonstrated through use of triangulation, bracketing, and participant review of the transcripts to ensure truthfulness. Eight themes were identified and are as follows: # 1 Its part of the job, # 2 They were there for me, # 3 Conflicted about pressing charges, # 4 Learn to prevent and deal with it, # 5 Workplace violence negatively impacts our job, # 6 Fear for our safety, # 7 Nurses go it alone and # 8 Feeling badly for others. The results of this study may have implications for future nursing research, nursing practice, nursing education, organizational policies and procedures, and healthcare policies. Recommendations were made for all of these areas in order to provide: Workplace Violence Prevention Programs; reporting mechanisms for workplace violence; empowerment for nurses; system changes to help extinguish oppression and patriarchal approaches to management and decision making; the establishment of a law similar to New York State’s Violence Against Nurses law to help prevent and prosecute perpetrators of workplace violence; interdisciplinary responsibility for preventing and dealing with workplace violence; and patient and family education regarding their responsibility of safe behavior while in the hospital; and education of the public about the role of the nurse. The results of this study indicate that workplace violence exists and there is much to be done to prevent and manage workplace violence against nurses who work on inpatient pediatric hospital units

Determination of shallow S-wave attenuation by down-hole waveform deconvolution: a case study in Istanbul (Turkey)

The estimation of shear-wave velocity and attenuation in near-surface geology is of primary importance in engineering seismology. In fact, their knowledge is essential for site response studies when preparing improved seismic hazard scenarios. In this study, we propose two approaches for estimating the average shear-wave quality factor Qs by using recordings of a vertical array of accelerometers. The methods are mainly based on the deconvolution of the wavefield recorded in a borehole with that recorded at the surface. The first method requires the Fourier transform of the deconvolved wavefield to be fitted with a theoretical transfer function valid for the vertical or nearly vertical (in the case at hand up to 30° incidence angle) propagation of S-waves. The second method is based on the spectral fitting of the Fourier transform of only the acausal part of the deconvolved wavefield with a theoretical transfer function. Both methods can be applied without any prior knowledge of the subsoil structure (since they are based on empirical data analysis) and do not require a precise knowledge of the azimuthal orientation of the sensors in the boreholes (which is seldom available). First, we describe the theoretical framework of the proposed methodologies for Qs estimation, which are based on the assumption that the structure in the borehole is weakly heterogeneous in the vertical direction (that is, no large impedance contrast exists between the borehole sensor and the surface). Second, by using synthetic accelerograms, we verify that in a realistic subsoil structure, the assumption of vertical homogeneity can hold and we investigate the robustness and the suitability of the proposed methods. Finally, only the method that was shown to provide the more stable results, based on fitting the borehole-to-surface spectral ratio with a theoretical function, is applied to earthquakes signals recorded by a vertical array of accelerometers installed in Ataköy (western Istanbul). Results show that using borehole data provides a fair and robust estimate of an average Qs (of about 30, 46 and 99 for the 0-50, 0-70, 0-140 m depth ranges, respectively), that can be used for numerical simulations of ground motion

Suitability of short-period sensors for retrieving reliable H/V peaks for frequencies less than 1 Hz

Using three different short-period electromagnetic sensors with resonant frequencies of 1 Hz (Mark L4C-3D), 2 Hz (Mark L-22D), and 4.5 Hz (I/O SM-6), coupled with three digital acquisition system, the PDAS Teledyne Geotech, the REFTEK 72A, and the Earth Data Logger PR6-24 (EDL), the effect of the seismic instruments on the horizontal-to-vertical spectral ratio (H/V) using seismic noise for frequencies less than 1 Hz has been evaluated. For all possible sensors - acquisition system pairs, the background seismic signal and instrumental self-noise power spectral densities have been calculated and compared. The results obtained when coupling the short-period sensors with different acquisition systems show that the performance of the considered instruments at frequencies < 1 Hz strongly depends upon the sensor-acquisition system combination and the gain used, with the best performance obtained for sensors with the lowest resonance frequency. For all acquisition systems, it was possible to retrieve correctly the H/V peak down to 0.1-0.2 Hz by using a high gain and a 1 Hz sensor. In contrast, biased H/V spectral ratios were retrieved when low-gain values were considered. Particular care is required when using 4.5 Hz sensors since they may not even allow the fundamental resonance frequency peak to be reproduce

trans-Resveratrol, Quercetin, (+)-Catechin, and (-)-Epicatechin Content in South Italian Monovarietal Wines: Relantionship with Maceration Time and Marc Pressing during Winemaking

The concentrations of trans-resveratrol, (+)-catechin, (-)-epicatechin, and quercetin were evaluated by means of high-performance liquid chromatography-diode array detection in red wines obtained from Aglianico, Piedirosso, and Nerello Mascalese grapes. The trans-resveratrol and epicatechin concentrations did not differ significantly between experimental wines. The concentration of quercetin in Nerello Mascalese wines was more than twice that observed in Aglianico and Piedirosso wines. Nerello Mascalese wines also significantly differed from other wines in the (+)-catechin content, which was significantly higher than those found in the other two wines. During maceration, the maximum extraction of trans-resveratrol was reached after 12 days for Aglianico and Piedirosso, after which a decline was observed. On the contrary, in the case of Nerello Mascalese, the concentration of trans-resveratrol increased steadily throughout the whole maceration process. After 2 days of maceration, the maximum concentration of quercetin was observed in Aglianico must, whereas the maximum quercetin extraction was reached after 12 days for Piedirosso and 17 days for Nerello Mascalese. The maximum levels of (+)-catechin and (-)-epicatechin were generally observed after 12 days of maceration for all wines, although a decline of (-)-epicatechin occurred after maximum extraction in Aglianico and Piedirosso wines. Following marc pressing, a significant increase in the concentration of trans-resveratrol for Aglianico, (+)-catechin and (-)-epicatechin for Piedirosso, and (-)-epicatechin for Nerello Mascalese was observed

Suitability of short-period sensors for retrieving reliable H/V peaks for frequencies less than 1 Hz

Using three different short-period electromagnetic sensors with resonant frequencies of 1 Hz (Mark L4C-3D), 2 Hz (Mark L-22D), and 4.5 Hz (I/O SM-6), coupled with three digital acquisition system, the PDAS Teledyne Geotech, the REFTEK 72A, and the Earth Data Logger PR6-24 (EDL), the effect of the seismic instruments on the horizontal-to-vertical spectral ratio (H/V) using seismic noise for frequencies less than 1 Hz has been evaluated. For all possible sensors - acquisition system pairs, the background seismic signal and instrumental self-noise power spectral densities have been calculated and compared. The results obtained when coupling the short-period sensors with different acquisition systems show that the performance of the considered instruments at frequencies < 1 Hz strongly depends upon the sensor-acquisition system combination and the gain used, with the best performance obtained for sensors with the lowest resonance frequency. For all acquisition systems, it was possible to retrieve correctly the H/V peak down to 0.1-0.2 Hz by using a high gain and a 1 Hz sensor. In contrast, biased H/V spectral ratios were retrieved when low-gain values were considered. Particular care is required when using 4.5 Hz sensors since they may not even allow the fundamental resonance frequency peak to be reproduce

Empirical H/V spectral ratios estimated in two deep sedimentary basins using microseisms recorded by short-period seismometers

In this work, we analyse continuous measurements of microseisms to assess the reliability of the fundamental resonance frequency estimated by means of the horizontal-to-vertical (H/V) spectral ratio within the 0.1–1 Hz frequency range, using short-period sensors (natural period of 1 s). We apply the H/V technique to recordings of stations installed in two alluvial basins with different sedimentary cover thicknesses—the Lower Rhine Embayment (Germany) and the Gubbio Plain (Central Italy). The spectral ratios are estimated over the time–frequency domain, and we discuss the reliability of the results considering both the variability of the microseism activity and the amplitude of the instrumental noise. We show that microseisms measured by short period sensors allow the retrieval of fundamental resonance frequencies greater than about 0.1–0.2 Hz, with this lower frequency bound depending on the relative amplitude of themicroseism signal and the self-noise of the instruments. In particular,we show an examplewhere the considered short-period sensor is connected to instruments characterized by an instrumental noise level which allows detecting only fundamental frequencies greater than about 0.4 Hz. Since the frequency at which the peak of the H/V spectral ratio is biased depends upon the seismic signal-to-instrument noise ratio, the power spectral amplitude of instrumental self-noise should be always considered when interpreting the frequency of the peak as the fundamental resonance frequency of the investigated site

Routine blood analysis greatly reduces the false-negative rate of RT-PCR testing for COVID-19

Background: The COVID-19 outbreak is now a pandemic disease reaching as much as 210 countries worldwide with more than 2.5 million infected people and nearly 200.000 deaths. Amplification of viral RNA by RT-PCR represents the gold standard for confirmation of infection, yet it showed false-negative rates as large as 15-20% which may jeopardize the effect of the restrictive measures taken by governments. We previously showed that several hematological parameters were significantly different between COVID-19 positive and negative patients. Among them aspartate aminotransferase and lactate dehydrogenase had pre-dictive values as large as 90%. Thus a combination of RT-PCR and blood tests could reduce the false-negative rate of the genetic test. Methods: We retrospectively analyzed 24 patients showing multiple and inconsistent RT-PCR, test during their first hospitalization period, and compared the genetic tests results with their AST and LDH levels. Results: We showed that when considering the hematological parameters, the RT-PCR false-negative rates were reduced by almost 4-fold. Conclusions: The study represents a preliminary work aiming at the development of strategies that, by combining RT-PCR tests with routine blood tests, will lower or even abolish the rate of RT-PCR false-negative results and thus will identify, with high accuracy, patients infected by COVID-19. (www.actabiomedica.it)

Influence of berry ripening stages over phenolics and volatile compounds in aged aglianicowine

The harvest time of grapes is a major determinant of berry composition and of the wine quality, and it is usually established through empirical testing of main biochemical parameters of the berry. In this work, we studied how the ripening stage of Aglianico grapes modulates key secondary metabolites of wines, phenolics and volatile compounds. Specifically, we analyzed and compared four berry ripening stages corresponding to total soluble solids of 18, 20, 22, and 25 Brix and related aged wines. Wine color intensity, anthocyanins level and total trans-resveratrol (free + glycosidic form) increased with grape maturity degree. Wines obtained from late-harvested grapes significantly differed from the others for a higher content of aliphatic alcohols, esters, acetates, a-terpineol and benzyl alcohol. The content of glycosidic terpene compounds, such as nerol, geraniol and a-terpineol, was higher in wines obtained with grapes harvested at 25 Brix compared to the earlier harvests. Our work indicated that the maturity of the grape is a determining factor in phenolic and volatile compounds of red Aglianico wines. Moreover, extending grape ripening to a sugar concentration higher than 22 Brix improves the biochemical profile of aged wine in terms of aroma compounds and of phytochemicals with known health-related benefits