A randomized prospective long-term (\u3e 1 year) clinical trial comparing the efficacy and safety of radiofrequency ablation to 980nm laser ablation of the great saphenous vein

Purpose To compare the short- and long-term (\u3e1 year) efficacy and safety of radiofrequency ablation (ClosureFAST™) versus endovenous laser ablation (980 nm diode laser) for the treatment of superficial venous insufficiency of the great saphenous vein. Materials and methods Two hundred patients with superficial venous insufficiency of the great saphenous vein were randomized to receive either radiofrequency ablation or endovenous laser ablation (and simultaneous adjunctive therapies for surface varicosities when appropriate). Post-treatment sonographic and clinical assessment was conducted at one week, six weeks, and six months for closure, complications, and patient satisfaction. Clinical assessment of each patient was conducted at one year and then at yearly intervals for patient satisfaction. Results Post-procedure pain (p \u3c 0.0001) and objective post-procedure bruising (p = 0.0114) were significantly lower in the radiofrequency ablation group. Improvements in venous clinical severity score were noted through six months in both groups (endovenous laser ablation 6.6 to 1; radiofrequency ablation 6.2 to 1) with no significant difference in venous clinical severity score (p = 0.4066) or measured adverse effects; 89 endovenous laser ablation and 87 radiofrequency patients were interviewed at least 12 months out with a mean long-term follow-up of 44 and 42 months (p = 0.1096), respectively. There were four treatment failures in each group, and every case was correctable with further treatment. Overall, there were no significant differences with regard to patient satisfaction between radiofrequency ablation and endovenous laser ablation (p = 0.3009). There were no cases of deep venous thrombosis in either group at any time during this study. Conclusions Radiofrequency ablation and endovenous laser ablation are highly effective and safe from both anatomic and clinical standpoints over a multi-year period and neither modality achieved superiority over the other

Relevance conversation between host and guest in Joe Rogan podcast

ENGLISH: Communication is very important and useful in everyday life. From communication, people can interact with each other and do many positive things in the world. Communication is an inseparable part of interaction and language. In this world, there are many varieties of languages spreaded throughout the world with their own uniqueness and characteristics. People, have to improve at least their own language to continue their activity in life. From the many languages spread in the world, English has an important role as a Lingua Franca which makes international interests use English as a means of communication. Regarding the research that the researcher did in this thesis, people need to know the relevance in conversation to understand the relevance of their conversation with the interlocutor. In order to know the relevance of a conversation, this is a function of relevance theory explaining this. The researcher examined the Relevance Conversation between Host and Guest in Podcast based on Relevance Theory. According to Sperber & Wilson (1995) Relevance theory is based on the definition of relevance and two principles of relevance, cognitive and communicative principles. The definition of relevance is "an assumption is relevant in a context if and only if it has some contextual effect in that context", The human brain is programmed to support the most relevant stimuli, thoughts, and ways of thinking, to produce maximum cognitive effect with the least amount of effort. This study aims to find out how relevance is represented between hosts and actors in podcasts, specifically Joe Rogan and Elon Musk. This research uses descriptive qualitative research method to explain the representation of relevance in conversation. The data source is taken from the Youtube platform with the code Joe Rogan Podcast#1470. INDONESIA: Komunikasi sangat penting dan berguna dalam kehidupan sehari-hari. Dari komunikasi, orang dapat berinteraksi satu sama lain dan melakukan banyak hal positif di dunia. Komunikasi merupakan bagian yang tidak terpisahkan dari interaksi dan bahasa. Di dunia ini terdapat banyak ragam bahasa yang tersebar di seluruh dunia dengan keunikan dan ciri khasnya masing-masing. Orang-orang, harus meningkatkan setidaknya bahasa mereka sendiri untuk melanjutkan hidup mereka. Dari sekian banyak bahasa yang tersebar di dunia, bahasa Inggris memiliki peran penting sebagai Lingua Franca yang membuat kepentingan internasional menggunakan bahasa Inggris sebagai alat komunikasi. Mengenai penelitian yang peneliti lakukan dalam tesis ini, orang perlu mengetahui relevansi percakapan untuk memahami relevansi percakapan mereka dengan lawan bicara. Untuk mengetahui relevansi suatu percakapan, inilah fungsi dari teori relevansi yang menjelaskan hal tersebut. Peneliti mengkaji Relevansi Percakapan antara Host dan Tamu di Podcast berdasarkan Teori Relevansi. Menurut Sperber & Wilson (1995) Teori relevansi didasarkan pada definisi relevansi dan dua prinsip relevansi, prinsip kognitif dan komunikatif. Definisi relevansi adalah "suatu asumsi relevan dalam suatu konteks jika dan hanya jika memiliki beberapa efek kontekstual dalam konteks itu", Otak manusia diprogram untuk mendukung rangsangan, pemikiran, dan cara berpikir yang paling relevan, untuk keluaran kognitif maksimum. . efek dengan sedikit usaha. Penelitian ini bertujuan untuk mengetahui bagaimana relevansi direpresentasikan antara pembawa acara dan aktor dalam podcast, khususnya Joe Rogan dan Elon Musk. Penelitian ini menggunakan metode penelitian deskriptif kualitatif untuk menjelaskan representasi relevansi dalam percakapan. Sumber data diambil dari platform Youtube dengan kode Joe Rogan Podcast#1470. ARABIC: التواصل مهم جدا ومفيد في الحياة اليومية. من خلال التواصل ، يمكن للناس التفاعل مع بعضهم البعض والقيام بالعديد من الأشياء الإيجابية في العالم. التواصل جزء لا يتجزأ من التفاعل واللغة. يوجد في هذا العالم العديد من أنواع اللغات المنتشرة في جميع أنحاء العالم مع تميزها وخصائصها. يجب على الناس تحسين لغتهم على الأقل للمضي قدمًا في حياتهم. من بين العديد من اللغات المنتشرة في العالم ، تلعب اللغة الإنجليزية دورًا مهمًا باعتبارها Lingua Franca مما يجعل الاهتمامات الدولية تستخدم اللغة الإنجليزية كوسيلة للتواصل. فيما يتعلق بالبحث الذي أجراه الباحث في هذه الأطروحة ، يحتاج الناس إلى معرفة أهمية المحادثة لفهم أهمية محادثتهم مع الشخص الآخر. لمعرفة مدى ملاءمة المحادثة ، هذه هي وظيفة نظرية الصلة التي تشرحها. يفحص الباحث أهمية المحادثات بين المضيفين والضيوف في ملفات البودكاست بناءً على نظرية الصلة. وفقًا لـ Sperber & Wilson (1995) ، تستند نظرية الصلة إلى تعريف الصلة ومبدأين يتعلقان بالموضوع ، والمبادئ المعرفية والتواصلية. تعريف الصلة هو "الافتراض المناسب في سياق ما إذا كان له بعض التأثير السياقي في هذا السياق فقط" ، تمت برمجة الدماغ البشري لدعم المحفزات والأفكار وطرق التفكير الأكثر صلة ، لتحقيق أقصى قدر من المخرجات المعرفية . . تأثير بأقل جهد. تهدف هذه الدراسة إلى معرفة كيفية تمثيل الصلة بين المقدمين والممثلين في البودكاست ، وتحديداً جو روجان وإيلون ماسك. تستخدم هذه الدراسة مناهج بحثية وصفية نوعية لشرح تمثيل الصلة بالموضوع في المحادثة. مصدر البيانات مأخوذ من منصة Youtube برمز .Joe Rogan Podcast # 147

Antibody to a cryptic, solid phase ClQ antigen in membranoproliferative nephritis

Antibody to a cryptic solid phase Clq antigen in membranoproliferative nephritis. IgG containing material detected in membranoproliferative nephritis (MPGN) serum with a solid phase (sp) Clq ELISA has been presumed to be immune complexes. However, in serum from 13 MPGN patients containing large amounts of spClq-binding material, sucrose density ultracentrifugation and sieve chromatography showed spClq-binding protein to sediment at 7S or cofractionate with IgG. One serum (stored for 12 years) contained, in addition, spClq-binding material sedimenting at more than 19S. Isolated MPGN IgG was shown to bind to spClq SpClq-binding material could be totally removed from MPGN serum by absorption with BSA-anti-BSA immune precipitates, and by acid elution of the precipitates IgG binding to spClq could be recovered. F(ab′)2, isolated from pepsin digested MPGN IgG, continued to bind spClq. Binding of MPGN IgG or F(ab′)2 to spClq was not inhibited by 2 M NaCl. Incubation of MPGN serum with 125I Clq followed by sucrose density ultracentrifugation resulted in a peak of radioactivity at 11S, the sedimentation rate of Clq, giving evidence that material binding fluid phase Clq is not present SpClq-binding IgG was detected in 54% of 68 MPGN patients. These results indicate that the 7S spClq-binding IgG represents antibody to a cryptic antigen revealed only when Clq fixes to a solid surface

Credentialing for radiology

Patients expect to receive safe, predictable and high-quality care delivered by competent professionals. Thus, it has become important to provide specific training in existing and new modalities and prove on-going clinical expertise. Hospital credentialing is the process by which the competence of a doctor is determined by the hospital management. In Australia, radiologists participate in a mandatory program of continuing professional development and are also required to maintain a logbook of procedures. The Conjoint Committee for the Recognition of Training in Peripheral Endovascular Therapy has been established to advise the respective subspecialty groups on the requirements for accreditation. This article examines some of the issues the committee has considered in preparing the criteria to assist institutions for the purposes of credentialing and gives an Australian perspective on future trends

Jazzing Up Next-Gen Librarians for Freshman Engineering Instruction Delivery

Because of the need for science and engineering librarians, both nationwide and at West Virginia University (WVU), a model of Introduction to STEM Disciplines’ Information Use and Mentoring occurred at WVU. The engineering librarians introduced new resident librarians and a graduate research assistant to the Freshman Engineering program and involved them in teaching several engineering information literacy sessions. The goal of engaging the new librarians into the educational activities was to motivate their learning, gain feedback on current teaching strategies and fresh ideas for possible future implementation, and facilitate buy-in of the need for and role of STEM-specific librarians. The new team members learned the specific information literacy resources for the engineering field, provided feedback on the teaching methods, offered new ideas for implementation, and engaged with the engineering faculty and current STEM librarians about possible modifications to the types of information offered and the timing of its delivery