450 research outputs found
Computer simulation of the aluminium extrusion process
The purpose of the work is computer simulation of the aluminium extrusion process using the Finite elements method (FEM). The impact of the speed of a punch falling on the material in the aluminium extrusion process was investigated. It was found that high stresses are created, leading to material destruction, if the punch is falling too fast. The design cycle is significantly reduced in multiple industrial applications if the FEM is applied, which enhances productivity and profits
Towards reliable diagnostics of prostate cancer via breath
Early detection of cancer is a key ingredient for saving many lives. Unfortunately, cancers of the urogenital system are difficult to detect at early stage. The existing noninvasive diagnostics of prostate cancer (PCa) suffer from low accuracy (< 70%) even at advanced stages. In an attempt to improve the accuracy, a small breath study of 63 volunteers representing three groups: (1) of 19 healthy, (2) 28 with PCa, (3) with 8 kidney cancer (KC) and 8 bladder cancer (BC) was performed. Ultrabroadband mid-infrared Fourier absorption spectroscopy revealed eight spectral ranges (SRs) that differentiate the groups. The resulting accuracies of supervised analyses exceeded 95% for four SRs in distinguishing (1) vs (2), three for (1) vs (3) and four SRs for (1) vs (2) + (3). The SRs were then attributed to volatile metabolites. Their origin and involvement in urogenital carcinogenesis are discussed
Micro-endoscopy of the human vas deferens: a feasibility study of a novel device in several ex vivo models
The aim of this study was to show limitation as well as potential of micro-endoscopy techniques as an innovative diagnostic and therapeutic approach in andrology. Two kinds of custom-made micro-endoscopes (ME) were tested in ex vivo vas deferens specimen and in post-mortem whole body. The semi-rigid ME included a micro-optic (0.9mm outer diameter [OD], 10.000 pixels, 120 degrees vision angle [VE], 3-20mm field depth [FD]) and an integrated fibre-optic light source. The flexible ME was composed of a micro-optic (OD=0.6mm, 6.000 pixels, 120 degrees VE, 3-20mm FD). The ex vivo study included retrograde investigation of the vas deferens (surgical specimen n=9, radical prostatectomy n=3). The post-mortem investigation (n=4) included the inspection of the vas deferens via both approaches. The results showed that antegrade and retrograde rigid endoscopy of the vas deferens were achieved as a diagnostic tool. The working channel enabled therapeutic use including biopsies or baskets. Using the flexible ME, the orifices of the ejaculatory ducts were identified. In vivo cadaveric retrograde cannulation of the orifices was successful. Post-mortem changes of verumontanum hindered the examinations beyond. Orifices were identified shaded behind a thin transparent membrane. Antegrade vasoscopy using flexible ME was possible up to the internal inguinal ring. Further advancement was impossible because of anatomical angle and lack adequate vision guidance. The vas deferens interior was clearly visible and was documented by pictures and movies. Altogether, the described ME techniques were feasible and effective, offering the potential of innovative diagnostic and therapeutic approaches for use in the genital tract. Several innovative indications could be expected
Preservation and Access of Illinois Newspapers
These presentations for the 2017 Conference on Illinois History discuss preservation and access of Illinois newspapers, specifically focusing on non-English newspapers published in Chicago. The first section addresses the history of newspaper preservation in libraries, looking into challenges Illinois libraries have faced historically, as well as those they will face in the future as they endeavor to steward a comprehensive record of journalism in print. The second section examines Polish-American newspapers in American and European digital collections and addresses the importance of including Polish-American newspaper content in the Library of Congress Chronicling America database. The third section explores the National Digital Newspaper Program (NDNP) and its goal of building an online, fully-searchable database of U.S. newspapers featuring curated digitized content. The final section discusses the 2016-2018 NDNP project at the U of I, evaluating complexities of making non-English content accessible and searchable.Ope
A hydrodynamically optimized nano-electrospray ionization source and vacuum interface
The coupling of atmospheric pressure ionization (API) sources like electrospray ionization (ESI) to vacuum based applications like mass spectrometry (MS) or ion beam deposition (IBD) is done by differential pumping, starting with a capillary or pinhole inlet. Because of its low ion transfer efficiency the inlet represents a major bottleneck for these applications. Here we present a nano-ESI vacuum interface optimized to exploit the hydrodynamic drag of the background gas for collimation and the reduction of space charge repulsion. Up to a space charge limit of 40 nA we observe 100% current transmission through a capillary with an inlet and show by MS and IBD experiments that the transmitted ion beams are well defined and free of additional contamination compared to a conventional interface. Based on computational fluid dynamics modelling and ion transport simulations, we show how the specific shape enhances the collimation of the ion cloud. Mass selected ion currents in the nanoampere range available further downstream in high vacuum open many perspectives for the efficient use of electrospray ion beam deposition (ES-IBD) as a surface coating method
Resource and Mobility Management in the Network Layer of 5G Cellular Ultra-Dense Networks
© 2017 IEEE. Personal use of this material is permitted. PermissĂon from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertisĂng or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.[EN] The provision of very high capacity is one of the big challenges of the 5G cellular technology. This challenge will not be met using traditional approaches like increasing spectral efficiency and bandwidth, as witnessed in previous technology generations. Cell densification will play a major role thanks to its ability to increase the spatial reuse of the available resources. However, this solution is accompanied by some additional management challenges. In this article, we analyze and present the most promising solutions identified in the METIS project for the most relevant network layer challenges of cell densification: resource, interference and mobility management.This work was performed in the framework of the FP7 project ICT-317669 METIS, which is partly funded by the European Union. The authors would like to acknowledge the contributions of their colleagues in METIS, although the views expressed are those of the authors and do not necessarily represent the project.Calabuig Soler, D.; Barmpounakis, S.; GimĂ©nez Colás, S.; Kousaridas, A.; Lakshmana, TR.; Lorca, J.; Lunden, P.... (2017). Resource and Mobility Management in the Network Layer of 5G Cellular Ultra-Dense Networks. IEEE Communications Magazine. 55(6):162-169. https://doi.org/10.1109/MCOM.2017.1600293S16216955
Development of an ex vivo model of endovenous laser ablation of the great saphenous vein in a pilot study
The effect of long-term impact of elevated temperature on changes in the microstructure of inconel 740H alloy
This paper presents the results of investigations on microstructure changes after the long-term impact of temperature. The microstructure investigations were carried out by light microscopy and scanning electron microscopy. The qualitative and quantitative identification of the existing precipitates was carried out using X-ray phase composition analysis. The effect of elevated temperature on precipitation processes of test material were described. The obtained results of investigations form part of the material characteristics of new-generation alloys, which can be indirectly associated with the stability of functional properties under the simultaneous effect of high temperature and stress
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