295 research outputs found
Health-related quality of life (HRQoL) assessment with once- and twice-daily darunavir/ritonavir (DRV/r) in the ODIN trial
Patient empowerment and the Mediterranean diet as a possible tool to tackle prediabetes associated with overweight or obesity: a pilot study
AIM:
The objective of this study was to investigate the effect of implementation of short-term patient empowerment as applied to Mediterranean diet (MD) adherence on metabolic and anthropometric parameters in prediabetic overweight or obese subjects.
METHODS:
The sample included 42 subjects with prediabetes, aged 18-75 years and with body mass index (BMI) > 25 kg/m2, who received dietary advice on MD by nutritionists during session groups every 2 weeks for 4 months. Data on energy caloric intake and macronutrient consumption were collected using a 7-day food diary record. Adherence to MD was investigated through the PREvención con DIeta MEDiterránea (PREDIMED) questionnaire. No advice was given regarding caloric restriction and physical activity. At baseline and at the end of the study, each subject underwent anthropometric, metabolic, and nutritional assessments.
RESULTS:
Approximately 40.5% of subjects had achieved restoration of normal glucose tolerance by the end of the study. Fasting plasma glucose, glycated hemoglobin (HbA1C), BMI, waist circumference, blood pressure, visceral adiposity index, triglycerides, and total and LDL cholesterol levels were significantly decreased, while HDL cholesterol had significantly increased by the end of the study. The subjects significantly increased adherence to MD, as assessed by the PREDIMED questionnaire at follow-up. A reduction of prevalence of the metabolic syndrome was also reported. Interestingly, the PREDIMED score correlated with HbA1C values at follow-up, after adjusting for BMI and total caloric intake.
CONCLUSIONS:
Implementation of short-term patient empowerment as applied to MD adherence was shown to improve anthropometric and metabolic parameters in prediabetic overweight or obese subjects. This is of considerable importance, given that diet must be the cornerstone of treatment in patients at high risk of developing type 2 diabetes
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Empowering Students’ Learning Achievement Through Project-Based Learning As Perceived By Electrical Instructors And Students
Purposes of this research were to find out factors empowering electrical students‘ learning achievement through Project-Based Learning (PBL) as perceived by instructors‘ and students‘ opinions. The sample chosen for this study were 247 electrical power instructors at vocational education institutes and 161 electrical students in the 3 rd and 4th year who were studying in the 1st semester of academic year 2006 at Electrical Education Department, Faculty of Industrial Education and Technology, King Mongkut‘s University of Technology Thonburi by using simple random sampling. The instrument used for data collection was 7 rating scales questionnaire. The reliability of the instrument calculated by Cronbach Alpha Coefficient was 0.8185 and 0.9839, respectively. The data were analysed by using mean ( ), Standard Deviation (S.D.) and Analysis of Factors by Principal Component Analysis technique: PCA, orthogonal rotation axis by Varimax Method. The results of the study on factors empowering electrical students‘ learning achievement through Project-Based Learning (PBL) were as follows: both instructors and students agreed on Interesting/Attention(0.799 and 0.885, respectively) while other factors such as Planning(0.722), Sharing Ideas(0.582), Thinking(0.576), Facilitating (0.547), Constructionism (0.540), Scientific Process (0.525), Multiple Intelligence (0.479), and Goal Setting(0.453) were perceived by instructors, and students‘ opinions were on Advising/Guiding(0.863), Thinking(0.661), Goal Setting (0.634), Multiple Intelligence(0.553), Scientific Process(0.528), Assisting(0.524), and Sharing Ideas (0.492), if not more so
Guida alla redazione degli atti amministrativi
La "Guida alla redazione degli atti amministrativi" intende fornire indicazioni per la redazione degli atti per tutti i funzionari della pubblica amministrazione. Si articola in tre parti: (a) la lingua degli atti, (b) la struttura del provvedimento amministrativo, (c) il rinvio ad altri atti. Ne è autore un gruppo di linguisti e giuristi facenti capo all'ITTIG-CNR (Istituto per le Tecniche e Tecnologie dell'Informazione Giuridica) e dell'Accademia della Crusca
Susceptibility of Mice to Trypanosoma evansi Treated with Human Plasma Containing Different Concentrations of Apolipoprotein L-1
The aim of this study was to test the susceptibility of mice to Trypanosoma evansi treated with human plasma containing different concentrations of apolipoprotein L-1 (APOL1). For this experiment, a strain of T. evansi and human plasma (plasmas 1, 2, and 3) from 3 adult males clinically healthy were used. In vivo test used 50 mice divided in 5 groups (A to E) with 10 animals in each group. Animals of groups B to E were infected, and then treated with 0.2 ml of human plasma in the following outline: negative control (A), positive control (B), treatment with plasma 1 (C), treatment with plasma 2 (D), and treatment with plasma 3 (E). Mice treated with human plasma showed an increase in longevity of 40.9±0.3 (C), 20±9.0 (D) and 35.6±9.3 (E) days compared to the control group (B) which was 4.3±0.5 days. The number of surviving mice and free of the parasite (blood smear and PCR negative) at the end of the experiment was 90%, 0%, and 60% for groups C, D, and E, respectively. The quantification of APOL1 was performed due to the large difference in the treatments that differed in the source plasma. In plasmas 1, 2, and 3 was detected the concentration of 194, 99, and 115 mg/dl of APOL1, respectively. However, we believe that this difference in the treatment efficiency is related to the level of APOL1 in plasmas
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