Evaluation of primary stability of single implants placed in fresh extraction sockets: a clinical trial

ABSTRACTDental implants have been used for the last 20 years. With the latest modern developments, however, minimally invasive protocols and immediate implants are currently used. The aim of this study was to evaluate the primary stability of a new implant design. Thirty immediate implants were placed and they all achieved successful osseointegration. Primary stability was reached with all the implants after the first apical threads. Within the limitations of the present study, the immediate implant approach seems to be a predictable treatment option, especially in conjunction with a specifically designed implant system

Exploiting Reaction-Diffusion Conditions to Trigger Pathway Complexity in the Growth of a MOF

Coordination polymers (CPs), including metal-organic frameworks (MOFs), are crystalline materials with promising applications in electronics, magnetism, catalysis, and gas storage/separation. However, the mechanisms and pathways underlying their formation remain largely undisclosed. Herein, we demonstrate that diffusion-controlled mixing of reagents at the very early stages of the crystallization process (i.e., within ≈40 ms), achieved by using continuous-flow microfluidic devices, can be used to enable novel crystallization pathways of a prototypical spin-crossover MOF towards its thermodynamic product. In particular, two distinct and unprecedented nucleation-growth pathways were experimentally observed when crystallization was triggered under microfluidic mixing. Full-atom molecular dynamics simulations also confirm the occurrence of these two distinct pathways during crystal growth. In sharp contrast, a crystallization by particle attachment was observed under bulk (turbulent) mixing. These unprecedented results provide a sound basis for understanding the growth of CPs and open up new avenues for the engineering of porous materials by using out-of-equilibrium conditions

Primary Stability Study in Implantology: Correlation of Micromovements to Bone Density and Peak Insertion Torque

In modern implantology, one of the relevant issues regards the assessment of the primary stability. In particular, the role played by micromevements and their effects on various factors such as the intertional torque and bone density are of highest interest. A detailed knowledge of interconnections would be of great clinical relevance in suggesting a more rational application of the immediate loading thus reducing the failure rate. However, the study of the correlations of insertional torque and cortical and cancellous bone densities led to controversial results concerning micromovements and finally the primary stability. We propose here a more focused study on direct evaluations of micromovements

Non-Profit Organizations as Facilitators of the Sustainable Social Innovation of Firms: An Italian Case Study

Non-profit organizations (NPOs) are becoming top players in the business arena and can significantly contribute to socially sustainable development by leading several open innovation (OI) processes. The present study investigated the functioning of an NPO (ELIS, based in Rome, Italy), that acts as an open innovation intermediary in a large consortium of enterprises. By adopting a mixedmethod approach, key aspects related to the NPO’s organizational culture, the OI management process within the consortium, as well as leadership skills and values were investigated among 77 employees and 8 managers of the NPO. Results showed that the managers’ approach to OI, teamwork, and market challenges significantly affected the NPO’s ability to produce OI among the consortium members. Moreover, empowering leadership, and a culture of trust and mistake acceptance were highly valued by the NPO in view of an effective OI performance. The study contributes to the current literature by highlighting the conditional factors of the NPO’s capability to create open innovation with enterprises, and push them toward societal change. Implications for OI development have been discussed

Tensile Test and Interface Retention Forces Between Wires and Composites in Lingual Fixed Retainers

Introduction: In daily orthodontic clinical practice retention is very important, and lingual retainers are part of this challenge. The failure of lingual retainers may be due to many factors. The aim of this study was to assess the retention forces and mechanical behavior of different types of wires matched with different kinds of composites in lingual retainers. Methods: A tensile test was performed on cylindrical composite test specimens bonded to orthodontic wires. The specimens were constructed using four different wires: a straight wire (Remanium .016 7.022\u2033 Dentaurum), two round twisted wires (Penta One .0215\u2033 Masel, Gold Penta Twisted .0215\u2033 Gold N'braces) and a rectangular braided wire (D-Rect .016 7.022\u2033 Ormco); and three composites: two micro-hybrids (Micro-Hybrid Enamel Plus HFO Micerium, and Micro-Hybrid SDR U Dentsply) and a micro-nano-filled composite (Micro-Nano-Filled Transbond LR 3M). The test was performed at a speed of 10mm/min on an Instr\uf6m device. The wire was fixed with a clamp. Results: The results showed that the bonding between wires and composites in lingual fixed retainers seemed to be lowest for rectangular smooth wires and increased in round twisted and rectangular twisted wires where the bonding was so strong that the maximum tension/bond strength was greater than the ultimate tensile strength of the wire. The highest values were in rectangular twisted wires. Concerning the composites, hybrid composites had the lowest interface bonding values and broke very quickly, while the nano- and micro-composites tolerated stronger forces and displayed higher bonding values. The best results were observed with the golden twisted wire and reached 21.46 MPa with the Transbond composite. With the rectangular braided wire the retention forces were so high that the Enamel Plus composite fractured when the load exceeded 154.6 N/MPa. When the same wire was combined with the Transbond LR either the wire or the composite broke when the force exceeded 240 N. Conclusions: The results of this study show that, when selecting a lingual retainer in daily clinical practice, not only must the patient's compliance and dependability be considered but also the mechanical properties and composition of different combinations of composites and wires

Unveiling Pathway Complexity in the Growth of a Spin-Crossover MOF via Engineered Liquid-Liquid Interfacial Reactions

Coordination polymers (CPs), including metal-organic frameworks (MOFs), have recently emerged as a platform to design new materials with novel applications in fields such as electronics, magnetism, catalysis, optics and gas storage/separation. However, the pathways followed and the mechanisms underlying their formation remain largely unknown and unresolved. Accordingly, the elucidation of associated growth mechanisms remains the key obstacle in accessing new properties and functions in such materials. Herein, we demonstrate that reaction-diffusion (RD) conditions accomplished within microfluidic reaction systems can be used to uncover different crystallization pathways undertaken by spin-crossover MOFs towards their thermodynamic products. Specifically, microfluidic RD mixing (providing kinetic control) enables two peculiar nucleation-growth pathways characterized by well-defined metastable intermediates, which have never been observed in bulk environments (under thermodynamic control). Contrarily, in the latter case, crystallization by particle attachment (mesoscale assembly) is observed. These unprecedented results provide a sound basis for understanding coordination polymer growth, and open up new avenues for the engineering of advanced functional materials.</b

Inside Cover: Exploiting Reaction-Diffusion Conditions to Trigger Pathway Complexity in the Growth of a MOF

How do you unveil pathway complexity in a crystallization process? In their Research Article on page 15920, Alessandro Sorrenti, Marco D′Abramo, Guillermo Mínguez Espallargas, Josep Puigmartí-Luis, and co-workers show that harnessing a reaction-diffusion (RD) process within a continuous flow microfluidic device, and on a millisecond timescale, is key to enable two unprecedented nucleation-growth pathways during a MOF synthesis