Assessment of Sodium Benzoate and Potassium Sorbate Preservatives and Artificial Color in Bulk Tomato Paste Samples in Qazvin, Iran

Tomato is one of the popular crops in the world and tomato paste is a product of it. Due to its wide application, quality control of this product is important. The goal of our study was to the assessment of potassium sorbate and sodium benzoate preservatives and artificial color in bulk tomato paste samples in Qazvin, Iran. In this study, 45 samples were analyzed by high-performance liquid chromatography (HPLC) to determine the preservatives. Benzoic acid was detected in 17 (37.78%) samples, ranging from nd not detected to 1896 mg kg-1 and Potassium sorbate was not detected in any of the samples. The detection of color in samples was done by the thin-layer chromatography method (TLC). Three samples (6.67%) had Pansio 4R artificial color. The mean and standard deviation of sodium benzoate in samples were 990.62 mg kg-1 and 396.07 mg kg-1 , respectively. According to the national standard of Iran for canned tomato paste, adding any kind of preservative and color to tomato paste is prohibited. The results show the importance monitoring of sodium benzoate and artificial colors in bulk tomato paste by health authorities

Assessment of Sodium Benzoate and Potassium Sorbate Preservatives and Artificial Color in Bulk Tomato Paste Samples in Qazvin, Iran

Tomato is one of the popular crops in the world and tomato paste is a product of it. Due to its wide application, quality control of this product is important. The goal of our study was to the assessment of potassium sorbate and sodium benzoate preservatives and artificial color in bulk tomato paste samples in Qazvin, Iran. In this study, 45 samples were analyzed by high-performance liquid chromatography (HPLC) to determine the preservatives. Benzoic acid was detected in 17 (37.78%) samples, ranging from nd not detected to 1896 mg kg-1 and Potassium sorbate was not detected in any of the samples. The detection of color in samples was done by the thin-layer chromatography method (TLC). Three samples (6.67%) had Pansio 4R artificial color. The mean and standard deviation of sodium benzoate in samples were 990.62 mg kg-1 and 396.07 mg kg-1 , respectively. According to the national standard of Iran for canned tomato paste, adding any kind of preservative and color to tomato paste is prohibited. The results show the importance monitoring of sodium benzoate and artificial colors in bulk tomato paste by health authorities

The global, regional, and national burden of adult lip, oral, and pharyngeal cancer in 204 countries and territories:A systematic analysis for the Global Burden of Disease Study 2019

Importance Lip, oral, and pharyngeal cancers are important contributors to cancer burden worldwide, and a comprehensive evaluation of their burden globally, regionally, and nationally is crucial for effective policy planning.Objective To analyze the total and risk-attributable burden of lip and oral cavity cancer (LOC) and other pharyngeal cancer (OPC) for 204 countries and territories and by Socio-demographic Index (SDI) using 2019 Global Burden of Diseases, Injuries, and Risk Factors (GBD) Study estimates.Evidence Review The incidence, mortality, and disability-adjusted life years (DALYs) due to LOC and OPC from 1990 to 2019 were estimated using GBD 2019 methods. The GBD 2019 comparative risk assessment framework was used to estimate the proportion of deaths and DALYs for LOC and OPC attributable to smoking, tobacco, and alcohol consumption in 2019.Findings In 2019, 370 000 (95% uncertainty interval [UI], 338 000-401 000) cases and 199 000 (95% UI, 181 000-217 000) deaths for LOC and 167 000 (95% UI, 153 000-180 000) cases and 114 000 (95% UI, 103 000-126 000) deaths for OPC were estimated to occur globally, contributing 5.5 million (95% UI, 5.0-6.0 million) and 3.2 million (95% UI, 2.9-3.6 million) DALYs, respectively. From 1990 to 2019, low-middle and low SDI regions consistently showed the highest age-standardized mortality rates due to LOC and OPC, while the high SDI strata exhibited age-standardized incidence rates decreasing for LOC and increasing for OPC. Globally in 2019, smoking had the greatest contribution to risk-attributable OPC deaths for both sexes (55.8% [95% UI, 49.2%-62.0%] of all OPC deaths in male individuals and 17.4% [95% UI, 13.8%-21.2%] of all OPC deaths in female individuals). Smoking and alcohol both contributed to substantial LOC deaths globally among male individuals (42.3% [95% UI, 35.2%-48.6%] and 40.2% [95% UI, 33.3%-46.8%] of all risk-attributable cancer deaths, respectively), while chewing tobacco contributed to the greatest attributable LOC deaths among female individuals (27.6% [95% UI, 21.5%-33.8%]), driven by high risk-attributable burden in South and Southeast Asia.Conclusions and Relevance In this systematic analysis, disparities in LOC and OPC burden existed across the SDI spectrum, and a considerable percentage of burden was attributable to tobacco and alcohol use. These estimates can contribute to an understanding of the distribution and disparities in LOC and OPC burden globally and support cancer control planning efforts

The burden of metabolic risk factors in North Africa and the Middle East, 1990–2019: findings from the Global Burden of Disease StudyResearch in context

Summary: Background: The objective of this study is to investigate the trends of exposure and burden attributable to the four main metabolic risk factors, including high systolic blood pressure (SBP), high fasting plasma glucose (FPG), high body-mass index (BMI), and high low-density lipoproteins cholesterol (LDL) in North Africa and the Middle East from 1990 to 2019. Methods: The data were retrieved from Global Burden of Disease Study 2019. Summary exposure value (SEV) was used for risk factor exposure. Burden attributable to each risk factor was incorporated in the population attributable fraction to estimate the total attributable deaths and disability-adjusted life-years (DALYs). Findings: While age-standardized death rate (ASDR) attributable to high-LDL and high-SBP decreased by 26.5% (18.6–35.2) and 23.4% (15.9–31.5) over 1990–2019, respectively, high-BMI with 5.1% (−9.0–25.9) and high-FPG with 21.4% (7.0–37.4) change, grew in ASDR. Moreover, age-standardized DALY rate attributed to high-LDL and high-SBP declined by 30.2% (20.9–39.0) and 25.2% (16.8–33.9), respectively. The attributable age-standardized DALY rate of high-BMI with 8.3% (−6.5–28.8) and high-FPG with 27.0% (14.3–40.8) increase, had a growing trend. Age-standardized SEVs of high-FPG, high-BMI, high-SBP, and high-LDL increased by 92.4% (82.8–103.3), 76.0% (58.9–99.3), 10.4% (3.8–18.0), and 5.5% (4.3–7.1), respectively. Interpretation: The burden attributed to high-SBP and high-LDL decreased during the 1990–2019 period in the region, while the attributable burden of high-FPG and high-BMI increased. Alarmingly, exposure to all four risk factors increased in the past three decades. There has been significant heterogeneity among the countries in the region regarding the trends of exposure and attributable burden. Urgent action is required at the individual, community, and national levels in terms of introducing effective strategies for prevention and treatment that account for local and socioeconomic factors. Funding: Bill & Melinda Gates Foundation