An X-ray investigation of Hickson 62

We studied the X-ray properties of the Hickson Compact Group HCG62, in order to determine the properties and dynamic and evolutionary state of its hot gaseous halo. Our analysis reveals that the X-ray diffuse halo has an extremely complex morphological, thermal and chemical structure. Two deep cavities, due to the presence of the AGN hosted by the central galaxy NGC 4778, are clearly visible in the group X-ray halo. The cavities appear to be surrounded by ridges of cool gas. The group shows a cool core associated with the dominant galaxy. In the outer regions the temperature structure is quite regular, while the metal abundance shows a more patchy distribution, with large Si/O and Si/Fe ratios.Comment: Published in the Proceedings of the "I Workshop of Astronomy and Astrophysics for Students", Eds. N.R. Napolitano & M. Paolillo, Naples, 19-20 April 2006 (astro-ph/0701577

Hickson 62.I. Kinematics of NGC4778

Detailed studies of the photometric and kinematical properties of compact groups of galaxies are crucial to understand the physics of galaxy interactions and to shed light on some aspects of galaxy formation and evolution. In this paper we present a kinematical and photometrical study of a member, NGC4778, of the nearest (z=0.0137) compact group: Hickson 62. Aims: The aim of this work was to investigate the existence of kinematical anomalies in the brightest group member, NGC4778 in order to constrain the dynamical status and the formation history of the group. Methods: We used long-slit spectra obtained with FORS1 at VLT, to measure line-of-sight velocity distributions by means of the Fourier Correlation Quotient method, and to derive the galaxy rotation curve and velocity dispersion profile. Results: Our analysis reveals that Hickson 62a, also known as NGC4778, is an S0 galaxy with kinematical and morphological peculiarities, both in its central regions (r < 5'') and in the outer halo. In the central regions, the rotation curve shows the existence of a kinematically decoupled stellar component, offset with respect to the photometric center. In the outer halo we find an asymmetric rotation curve and a velocity dispersion profile showing a rise on the SW side, in direction of the galaxy NGC4776. Conclusions: The nuclear counterrotation, the distorted kinematics in the outer halo and the X-ray properties of the group suggest that NGC4778 may be the product of a recent minor merger, more reliable with a small late-type galaxy.Comment: 18 pages, 8 figures, accepted for pubblication in Astronomy and Astrophysic

Second hematopoietic SCT in patients with thalassemia recurrence following rejection of the first graft

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2021 Thalassaemia International Federation Guidelines for the Management of Transfusion-dependent Thalassemia

Beta-thalassemia and particularly its transfusion-dependent form (TDT) is a demanding clinical condition, requiring life-long care and follow-up, ideally in specialized centers and by multidisciplinary teams of experts. Despite the significant progress in TDT diagnosis and treatment over the past decades that has dramatically improved patients' prognosis, its management remains challenging. On one hand, diagnostic and therapeutic advances are not equally applied to all patients across the world, particularly in several high-prevalence eastern regions. On the other, healthcare systems in low-prevalence western countries that have recently received large numbers of migrant thalassemia patients, were not ready to address patients' special needs. Thalassaemia International Federation (TIF), a global patient-driven umbrella federation with 232 member-associations in 62 countries, strives for equal access to quality care for all patients suffering from thalassemia or other hemoglobinopathies in every part of the world by promoting education, research, awareness, and advocacy. One of TIF's main actions is the development and dissemination of clinical practice guidelines for the management of these patients. In 2021, the fourth edition of TIF's guidelines for the management of TDT was published. The full text provides detailed information on the management of TDT patients and the clinical presentation, pathophysiology, diagnostic approach, and treatment of disease complications or other clinical entities that may occur in these patients, while also covering relevant psychosocial and organizational issues. The present document is a summary of the 2021 TIF guidelines for TDT that focuses mainly on clinical practice issues and recommendations

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