667 research outputs found
First-Class Nonstandard Interpretations by Opening Closures
We motivate and discuss a novel functional programming construct
that allows convenient modular run-time nonstandard interpretation
via reflection on closure environments. This map-closure construct
encompasses both the ability to examine the contents of a
closure environment and to construct a new closure with a modified
environment. From the user’s perspective, map-closure is a
powerful and useful construct that supports such tasks as tracing,
security logging, sandboxing, error checking, profiling, code instrumentation
and metering, run-time code patching, and resource
monitoring. From the implementor’s perspective, map-closure
is analogous to call/cc. Just as call/cc is a non-referentiallytransparent
mechanism that reifies the continuations that are only
implicit in programs written in direct style, map-closure is a nonreferentially-
transparent mechanism that reifies the closure environments
that are only implicit in higher-order programs. Just as
CPS conversion is a non-local but purely syntactic transformation
that can eliminate references to call/cc, closure conversion
is a non-local but purely syntactic transformation that can eliminate
references to map-closure. We show how the combination
of map-closure and call/cc can be used to implement set! as
a procedure definition and a local macro transformation
Binding of antigen by immunocytes. II. Effect of specific Ig on antigen binding by MOPC 315 cells.
Ontogeny of B-lymphocyte function. II. Ability of endotoxin to increase the heterogeneity of affinity of the immune response of B lymphocytes from fetal mice.
Assimilation of stratospheric and mesospheric temperatures from MLS and SABER into a global NWP model
International audienceThe forecast model and three-dimensional variational data assimilation components of the Navy Operational Global Atmospheric Prediction System (NOGAPS) have each been extended into the upper stratosphere and mesosphere to form an Advanced Level Physics High Altitude (ALPHA) version of NOGAPS extending to ~100 km. This NOGAPS-ALPHA NWP prototype is used to assimilate stratospheric and mesospheric temperature data from the Microwave Limb Sounder (MLS) and the Sounding of the Atmosphere using Broadband Radiometry (SABER) instruments. A 60-day analysis period in January and February, 2006, was chosen that includes a well documented stratospheric sudden warming. SABER temperatures indicate that the SSW caused the polar winter stratopause at ~40 km to disappear, then reform at ~80 km altitude and slowly descend during February. The NOGAPS-ALPHA analysis reproduces this observed stratospheric and mesospheric temperature structure, as well as realistic evolution of zonal winds, residual velocities, and Eliassen-Palm fluxes that aid interpretation of the vertically deep circulation and eddy flux anomalies that developed in response to this wave-breaking event. The observation minus forecast (O-F) standard deviations for MLS and SABER are ~2 K in the mid-stratosphere and increase monotonically to about 6 K in the upper mesosphere. Increasing O-F standard deviations in the mesosphere are expected due to increasing instrument error and increasing geophysical variance at small spatial scales in the forecast model. In the mid/high latitude winter regions, 10-day forecast skill is improved throughout the upper stratosphere and mesosphere when the model is initialized using the high-altitude analysis based on assimilation of both SABER and MLS data
Search for extended gamma-ray emission from the Virgo galaxy cluster with Fermi-LAT
Galaxy clusters are one of the prime sites to search for dark matter (DM)
annihilation signals. Depending on the substructure of the DM halo of a galaxy
cluster and the cross sections for DM annihilation channels, these signals
might be detectable by the latest generation of -ray telescopes. Here
we use three years of Fermi Large Area Telescope (LAT) data, which are the most
suitable for searching for very extended emission in the vicinity of nearby
Virgo galaxy cluster. Our analysis reveals statistically significant extended
emission which can be well characterized by a uniformly emitting disk profile
with a radius of 3\deg that moreover is offset from the cluster center. We
demonstrate that the significance of this extended emission strongly depends on
the adopted interstellar emission model (IEM) and is most likely an artifact of
our incomplete description of the IEM in this region. We also search for and
find new point source candidates in the region. We then derive conservative
upper limits on the velocity-averaged DM pair annihilation cross section from
Virgo. We take into account the potential -ray flux enhancement due to
DM sub-halos and its complex morphology as a merging cluster. For DM
annihilating into , assuming a conservative sub-halo model
setup, we find limits that are between 1 and 1.5 orders of magnitude above the
expectation from the thermal cross section for
. In a more optimistic scenario, we
exclude
for for the same channel. Finally, we
derive upper limits on the -ray-flux produced by hadronic cosmic-ray
interactions in the inter cluster medium. We find that the volume-averaged
cosmic-ray-to-thermal pressure ratio is less than .Comment: 15 pages, 11 figures, 4 tables, accepted for publication in ApJ;
corresponding authors: T. Jogler, S. Zimmer & A. Pinzk
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