A Rare Cause of Pruritus That is Seen Frequently in Hemodialysis Patients: Kyrle's Disease

WOS: 000417359300027Uremic pruritus is a common complication of chronic renal failure. It affects approximately half of patients undergoing dialysis treatment. Even if the pruritus is not hazardous alone, it causes physical and mental fatigue, insomnia, chronic fatigue, decrease in self care ability and life quality. The causes of pruritus and the pathophysiology are stil not fully understood. Xerosis, intradermal microprecipitation of divalent ions, secondary hyperparathyroidism, peripheral neuropathy, allergic reactions, hypersensitivity and histamine have been considered as pathogenetic factors. Kyrle's disease is a rare disorder of keratinization which is one of the perforating disorders of the skin. Herein, we report a case of Kyrle's disease which is seen rarely, as a cause of pruritus in a 68 year old female patient who is on regular hemodialysis treatment secondary to end stage renal failure due to diabetic nephropathy, in the light of existing literature

HAND-ASSISTED RETROPERITONEOSCOPIC DONOR NEPHRECTOMY OFFERS MORE LIBERAL USE OF RIGHT KIDNEYS: AN EXPERIENCE OF 455 CASES

WOS: 000367726700281

RIGHT-SIDED DONOR NEPHRECTOMY WITH HAND-ASSISTED RETROPERITONEOSCOPIC APPROACH OFFERS INCREASED SAFETY WITH EXCELLENT OUTCOME

WOS: 000367726703009

THE USE OF HAND ASSISTED RETROPERITONEOSCOPIC NEPHRECTOMY TECHNIQUE FOR SINGLE INCISION SIMULTANEOUS NATIVE NEPHRECTOMY AND LIVING DONOR KIDNEY TRANSPLANTATION: REPORT OF TWO CASES

WOS: 000411688503410

THE ASSESSMENT OF RENAL TRANSPLANT PATIENTS REGARDING MICRO-ELIMINATION OF CHRONIC VIRAL HEPATITISES IN TURKEY: AN ANALYSIS OF 2410 PATIENTS

WOS: 000491488703132[No abstract available

Clinical Prognosis of Renal Retransplant Patients: A Single-Center Experience

1st International Transplant Network Congress -- OCT 17-21, 2018 -- Antalya, TURKEYWOS: 000487349900032PubMed: 31474292Background. Retransplantation is a treatment option in patients with end-stage renal failure due to graft loss. Outcomes of these patients due to high immunologic risk remain unclear. the aim of this study was to evaluate outcomes of renal retransplantation patients retrospectively. Methods. Renal retransplant patients in our unit were evaluated retrospectively between 2010 and 2018. Patients' demographic characteristics, primary diseases, the causes of prior graft loss, immunologic status, desensitization protocols, the induction and maintenance treatments, the complications during the follow-up period, numbers of acute rejections, and the clinical prognosis were all detected from the patients' files. Results. We retrospectively evaluated 17 patients who underwent a second or third renal allograft. of these, 16 received a second and the remaining 1 patient received a third renal allograft. Immunologically, all of the 17 patients had negative flow cytometry crossmatch, 1 patient had a positive complement-dependent cytotoxicity crossmatch (Auto 12%), 16 patients had positive panel reactive antibody, the median HLA-mismatch was 3.5, and the score of donor-specific antibody relative intensity score (RIS) was 6.4 +/- 6.3. Ten pretransplant patients had desensitization treatment. While scores for HLA-MM and HLA-RIS in the patients who had a desensitization therapy were determined higher, no statistical difference was observed (respectively, P = .28 and.55). No acute rejection episode developed. BK virus DNA viremia was detected in 4 patients during the posttransplant 6th month. We observed no patient death or no graft loss during the follow-up period. Conclusion. Although the retransplant patients who had a graft loss previously have high immunologic risks, retransplantation is reliable in these patients, but they should be followed up carefully in terms of BKV nephropathy

Incisional Complications and Cosmetic Evaluation After Hand-assisted Retroperitoneoscopic Donor Nephrectomy

1st International Transplant Network Congress -- OCT 17-21, 2018 -- Antalya, TURKEYAydogdu, Ibrahim/0000-0001-7900-8598; SARDOGAN, CEYDA/0000-0002-4263-3653WOS: 000487349900018PubMed: 31474288Purpose. Hand-assisted retroperitoneoscopic (HARP) donor nephrectomy prevents major complications, but incision site complications may be more frequent in hand-assisted approach. We evaluated long-term incisional complication rates and cosmetic outcomes after HARP donor nephrectomy in our series. Materials and Methods. A total of 609 donors who underwent nephrectomy between February 2009 and June 2016 were invited for physical examination and face-to-face interview. A total of 209 donors (35.3%) participated to the study. Sex, age, body mass index (BMI), mean follow-up period, incision-related outcomes of cosmesis, and postoperative complications were evaluated. Body image scale (BIS) and cosmetic scale (CS) (scar test) questionnaires were applied. Higher cosmesis and body image scores indicated greater satisfaction. Results. A total of 191 donors had paramedian (91.4%), and 18 donors had Pfannenstiel incision (8.6%); 121 donors were female (57.9%). the donor mean age and BMI were 49.1 (SD, 1.8) years and 29.7 (SD, 5.1), respectively. Body mass index was significantly lower in the Pfannenstiel group (P < .001). the mean BIS score was 18.9 (SD, 1.8), and the CS questionnaire score was 19.3 (SD, 4,7). the BIS score was significantly better in donors with Pfannenstiel incisions (P < .001), but there was no statistical significance in CS score. the total rate of wound infection was 4.8%, and rate of incisional hernia was 4.8%. the rate of incisional hernia was more frequent in donors with paramedian incision (5.2%), but there was no statistical significance. Six donors (2.9%) required rehospitalization because of incision site complications. Conclusion. Hand-assisted retroperitoneoscopic donor nephrectomy avoids intra-abdominal complications, but rate of incision site complications can be higher in hand-assisted procedure. the donors were convinced from the cosmetic outcome after HARP donor nephrectomy. the ones who had Pfannenstiel incision had better satisfaction according to BIS score

The incidence of new onset diabetes after transplantation and related factors: Single center experience

WOS: 000400322000009PubMed ID: 28262264Aim: New-onset diabetes after transplantation (NODAT) is a frequent metabolic complication and is considered a risk factor for patients undergoing renal transplant. The aim of this study was to evaluate the incidence and developing duration of new-onset diabetes after transplant (NODAT) and influencing factors. Methods: All patients' data was investigated retrospectively. Diabetics, follow-up period < 6 months, age < 18years were excluded. Demographic, clinical and laboratory data was recorded. Patients were divided into two groups: with/without NODAT. NODAT group was divided into four subgroups according to the time of developing NODAT, which were 0-3, 3-6, 6-12 and 12 months later. Two groups were compared, to investigate the incidence of NODAT and risk factors associated with the occurrence of NODAT. Results: We retrospectively analyzed the records of 570 patients, of which 420 patients were included. Seventy (16.6%) patients had NODAT (36 female, mean age 51.7 +/- 8.2 years, mean follow-up 41.6 +/- 21.5 months), 52.8% of patients developed NODAT within the first three months of being diagnosed. 350 patients (116 female, mean age 43.2 +/- 12.5 years, mean follow-up 41.6 21.5 months) were without NODAT. The incidence of impaired fasting glucose (IFG) during the first week after transplant was found to be higher in the patients with NODAT (p <0.001). There was positive correlation between NODAT and older age, obesity, family history of diabetes, presence of IFG, fasting plasma glucose, total and LDL-cholesterol, triglycerides, parathormone. Old age, obesity, presence of IFG, pretransplant hypertriglyceridemia and hyperparathyroidism were predictors of development of NODAT. Conclusion: Incidence of NODAT, especially the first six months, was high. All patients should be screened for IFG within the first week. Patients with dyslipidemia, elderly and obese patients should be closely monitored for the risk of development of NODAT. (C) 2017 Sociedad Espanola de Nefrologia. Published by Elsevier Espana, S.L.U