Extinction and the Dimming of KIC 8462852

To test alternative hypotheses for the behavior of KIC 8462852, we obtained measurements of the star over a wide wavelength range from the UV to the mid-infrared from October 2015 through December 2016, using Swift, Spitzer and at AstroLAB IRIS. The star faded in a manner similar to the long-term fading seen in Kepler data about 1400 days previously. The dimming rate for the entire period reported is 22.1 +\- 9.7 milli-mag/yr in the Swift wavebands, with amounts of 21.0 +\- 4.5 mmag in the groundbased B measurements, 14.0 +\- 4.5 mmag in V, and 13.0 +\- 4.5 in R, and a rate of 5.0 +\- 1.2 mmag/yr averaged over the two warm Spitzer bands. Although the dimming is small, it is seen at >= 3 sigma by three different observatories operating from the UV to the IR. The presence of long-term secular dimming means that previous SED models of the star based on photometric measurements taken years apart may not be accurate. We find that stellar models with T_{eff} = 7000 - 7100 K and A_V ~ 0.73 best fit the Swift data from UV to optical. These models also show no excess in the near-simultaneous Spitzer photometry at 3.6 and 4.5 microns, although a longer wavelength excess from a substantial debris disk is still possible (e.g., as around Fomalhaut). The wavelength dependence of the fading favors a relatively neutral color (i.e., R_V >= 5, but not flat across all the bands) compared with the extinction law for the general ISM (R_V = 3.1), suggesting that the dimming arises from circumstellar material.Comment: accepted by the Astrophysical Journal; acknowledgements revised 9/1/201

An EUV Study of the Intermediate Polar EX Hydrae

On 2000 May 5, we began a large multi-wavelength campaign to study the intermediate polar, EX Hydrae. The simultaneous observations from six satellites and four telescopes were centered around a one million second observation with EUVE. Although EX Hydrae has been studied previously with EUVE, our higher signal-to-noise observations present new results and challenge the current IP models. Previously unseen dips in the light curve are reminiscent of the stream dips seen in polar light curves. Also of interest is the temporal extent of the bulge dip; approximately 0.5 in phase, implying that the bulge extends over half of the accretion disk. We propose that the magnetic field in EX Hydrae is strong enough (a few MG) to begin pulling material directly from the outer edge of the disk, thereby forming a large accretion curtain which would produce a very broad bulge dip. This would also result in magnetically controlled accretion streams originating from the outer edge of the disk. We also present a period analysis of the photometric data which shows numerous beat frequencies with strong power and also intermittent and wandering frequencies, an indication that physical conditions within EX Hya changed over the course of the observation. Iron spectral line ratios give a temperature of log T=6.5-6.9 K for all spin phases and a poorly constrained density of n_e=10^10-10^11 cm^-3 for the emitting plasma. This paper is the first in a series detailing our results from this multi-wavelength observational campaign.Comment: 27 pages, 7 figures, accepted for publication in Ap

Curvature-Induced Defect Unbinding in Toroidal Geometries

Toroidal templates such as vesicles with hexatic bond orientational order are discussed. The total energy including disclination charges is explicitly computed for hexatic order embedded in a toroidal geometry. Related results apply for tilt or nematic order on the torus in the one Frank constant approximation. Although there is no topological necessity for defects in the ground state, we find that excess disclination defects are nevertheless energetically favored for fat torii or moderate vesicle sizes. Some experimental consequences are discussed.Comment: 12 pages, 15 eps figure

Delayed Decision-making in Real-time Beatbox Percussion Classification

This is an electronic version of an article published in Journal of New Music Research, 39(3), 203-213, 2010. doi:10.1080/09298215.2010.512979. Journal of New Music Research is available online at: www.tandfonline.com/openurl?genre=article&issn=1744-5027&volume=39&issue=3&spage=20

Alteration of intracellular cysteine and glutathione levels in alveolar macrophages and lymphocytes by diesel exhaust particle exposure.

The purpose of this study was to characterize the effects of diesel exhaust particles (DEP) on thiol regulation in alveolar macrophages (AM) and lymphocytes. We obtained AM and lymph node (thymic and tracheal) cells (LNC) (at different time points) from rats exposed intratracheally to DEP (5 mg/kg) or saline, and measured inflammatory markers, thiol levels, and glutathione reductase (GSH-R) activity. DEP exposure produced significant increases in neutrophils, lactate dehydrogenase, total protein, and albumin content in the lavage fluid. AM from DEP-exposed rats showed a time-dependent increase in intracellular cysteine (CYSH) and GSH. In LNC the intracellular GSH reached peak level by 24 hr, declining toward control levels by 72 hr after exposure. LNC-CYSH and AM-CYSH and GSH were increased at both 24 and 72 hr. Both Sprague-Dawley and Brown Norway rats showed similar trends of responses to DEP exposure as per measurement of the inflammatory markers and thiol changes. AM and, to a lesser degree, LNC were both active in cystine uptake. The DEP exposure stimulated GSH-R activity and increased the conversion of cystine to CYSH in both cell types. The intracellular level of GSH in DEP-exposed AM was moderately increased compared with the saline control, and was further augmented when cells were incubated with cystine. In contrast, the intracellular level of GSH in DEP-exposed LNC was significantly reduced despite the increased CYSH level and GSH-R activity when these cells were cultured for 16 hr. DEP absorbed 23-31% of CYSH, cystine, and GSH, and only 8% of glutathione disulfide when incubated in cell free media. These results indicate that DEP exposure caused lung inflammation and affected thiol levels in both AM and LNC

Alteration of pulmonary immunity to Listeria monocytogenes by diesel exhaust particles (DEPs). I. Effects of DEPs on early pulmonary responses.

It has been hypothesized that diesel exhaust particles (DEPs) aggravate pulmonary bacterial infection by both innate and cell-mediated immune mechanisms. To test this hypothesis, we investigated the effects of DEP exposure on the functions of alveolar macrophages (AMs) and lymphocytes from lung-draining lymph nodes using a rat Listeria monocytogenes infection model. In the present study, we focused on the effects of DEP exposure on AM functions, including phagocytic activity and secretion of proinflammatory cytokines. The Listeria infection model was characterized by an increase in neutrophil count, albumin content, and acellular lactate dehydrogenase activity in the bronchoalveolar lavage (BAL) fluid at 3 and 7 days postinfection. Short-term DEP inhalation (50 and 100 mg/m(3), 4 hr) resulted in a dose-dependent suppression of lung clearance of Listeria, with the highest bacteria count occurring at day 3. This aggravated bacterial infection was consistent with the inhibitory effect of DEPs on macrophage functions. DEPs suppressed phagocytosis and Listeria-induced basal secretion of interleukin-1ss (IL-1ss) and IL-12 by AMs in a dose-dependent manner. The amount of IL-1ss and IL-12 in the BAL fluid was also reduced by DEP exposure. In addition, DEPs decreased Listeria-induced lipopolysaccharide-stimulated secretion of tumor necrosis factor-alpha (TNF-alpha), IL-1ss, and IL-12 from AMs. These results suggest that DEPs retard bacterial clearance by inhibiting AM phagocytosis and weaken the innate immunity by inhibiting AM secretion of IL-1ss and TNF-alpha. DEPs may also suppress cell-mediated immunity by inhibiting AM secretion of IL-12, a key cytokine for the initiation of T helper type 1 cell development in Listeria infection

Goal disruption theory, military personnel, and the creation of merged profiles: A mixed method investigation

The present study provides an example of the integrated data analysis technique of creating and interpreting merged profiles. By using this approach to merging data sources, we gained unique insight into goal disruption theory (GDT). Qualitative data suggest that military personnel harbor a wide range of desired end-states. Quantitative data support a component of GDT, suggesting that participants who have a strong need for desired end-state displayed greater purposive harm endurance. Interpretation of merged profiles revealed caveats to this relationship, in particular that not all end-states are equally motivating. Results illustrate the benefits of the integrated data analysis technique of creating and interpreting merged profiles. Utilization of the merged profiles illuminated relationships that would not have been exposed otherwise

Port-access coronary artery bypass grafting: A proposed surgical method

AbstractMinimally invasive surgical methods have been developed to provide patients the benefits of open operations with decreased pain and suffering. We have developed a system that allows the performance of cardiopulmonary bypass and myocardial protection with cardioplegic arrest without sternotomy or thoracotomy. In a canine model, we successfully used this system to anastomose the internal thoracic artery to the left anterior descending coronary artery in nine of 10 animals. The left internal thoracic artery was dissected from the chest wall, and the pericardium was opened with the use of thoracoscopic techniques and single lung ventilation. The heart was arrested with a cold blood cardioplegic solution delivered through the central lumen of a balloon occlusion catheter (Endoaortic Clamp; Heartport, Inc., Redwood City, Calif.) in the ascending aorta, and cardiopulmonary bypass was maintained with femorofemoral bypass. An operating microscope modified to allow introduction of the 3.5× magnification objective into the chest was positioned through a 10 mm port over the site of the anastomosis. The anastomosis was performed with modified surgical instruments introduced through additional 5 mm ports. In the cadaver model (n = 7) the internal thoracic artery was harvested and the pericardium opened by means of similar techniques. A precise arteriotomy was made with microvascular thoracoscopic instruments under the modified microscope on four cadavers. In three other cadavers we assessed the exposure provided by a small anterior incision (4 to 6 cm) over the fourth intercostal space. This anterior port can assist in dissection of the distal internal thoracic artery and provides direct access to the left anterior descending, circumflex, and posterior descending arteries. We have demonstrated the potential feasibility of grafting the internal thoracic artery to coronary arteries with the heart arrested and protected, without a major thoracotomy or sternotomy. (J THORAC CARDIOVASC SURG 1996;111:567-73