Chelyshkov Collocation Method for Solving Three-Dimensional linear Fredholm Integral Equations

The main purpose of this work is to use the Chelyshkov-collocation method for the solution of three- dimensional Fredholm integral equations. The method is based on the approximate solution in terms of Chelyshkov polynomials with unknown coefficients. This method transforms the integral equation to a system of linear algebraic equations by means of collocation points. Finally, numerical results are included to show the validity and applicability of the method and comparisons are made with existing results

Esophageal Obstruction in Buffaloes (Bubalus bubalis) Resulting from the Ingestion of Potato Tubers

Total 32 emergency cases of buffaloes with esophageal obstruction resulting from the ingestion of potato tubers during their grazing are described. Treatment comprised immediate rumen trocarisation by a 14g syringe, premedication with IM xylazine (0.05 mg/kg), and passing a designed stout flexible tube to dislodge the obstruction to the rumen. The results were 100% successful recovery without any complications

Design of Extended Channel Ge-source TFET for Low Power Applications

In this paper, a novel design of a TFET structure using Ge-source and extending a part of the channel into the source is proposed. The DC performance is analyzed by evaluating the ON current, ION/IOFF ratio and subthreshold swing (SS). Moreover, the high-frequency performance is inspected in terms of transconductance (gm) and unit-gain cutoff frequency (fT). All simulations are performed utilizing 2D SILVACO TCAD. It is demonstrated that the ON current and the cut-off frequency can be simultaneously improved by appropriate design of the proposed structure

Thelotomy in a dairy buffalo after ultrasonographic diagnosis

Teat stenosis was surgically treated by thelototomy and excision of fibrous stenosis following teat ultrasonography to determine the location and extent of the lesion in a dairy water buffal

Diode Laser Ablation Versus Surgical Scalpel Technique For Gingival Depigmentation: A Randomized Controlled Clinical Trial

The aim of this study is to evaluate and compare the clinical efficiency of gingival depigmentation procedure with conventional scalpel and diode laser techniques. Materials and methods: This study was carried out as a randomized controlled clinical trial, split mouth design, in which fifteen patients having diffuse continuous physiologic pigmentation of the gingiva involving facial aspect of maxillary right to left premolar area were selected. The maxilla was divided into two halves and randomly allotted for “study site” for depigmentation with diode laser technique, and “control site” for depigmentation with scalpel technique. The studied variables were the degree of pain, bleeding, duration of the procedure, wound healing, and level of melanin repigmentation. The follow-up period was twelve months. For statistical analysis, Wilcoxon signed-rank test were conducted. Results: The diode laser technique showed better results regarding pain during the first three days, duration of the procedure, and bleeding. There was no significant difference between diode laser technique and scalpel technique regarding the wound healing and pain experienced by the patient after one week of surgery. Both sites showed recurrence of pigmentation, yet it was after a shorter period on the scalpel site. Conclusion: The findings of the present study suggest that gingival depigmentation was effective with both scalpel and laser techniques. However, the laser treated sites showed reduced pain experienced by the patient and better operator comfort. Melanin repigmentation was observed on sites treated with scalpel and diode laser, yet faster on the scalpel technique sites

Relation between Interleukin 8 and Bronchial Asthma in Children: Review Article

Background: Asthma is a frequent respiratory condition to treat. A persistent airway inflammation characterizes this frequent form of pulmonary disease. Immune responses are triggered by cytokines and chemokines produced by airway epithelial cells. Human bronchial epithelial cells secrete IL-8 in response to the presence of interleukin-4 (IL-4) and interleukin-13, both of which are increased in asthmatics. There are two receptors for IL-8, the IL-8 receptor alpha (also known as CXCR1) and beta (also known as the IL-8 RB, CXCR2). IL8 is a potent chemotactic cytokine that activates inflammatory cells by recruiting mast cells, mononuclear phagocytes T lymphocytes, and neutrophils to the site of inflammation. Objective: To determine the relationship between IL8 and bronchial asthma in children. Conclusion: The assessment of IL8 levels in pediatric asthmatic patients is a useful biomarker reflecting the status of asthma and also to glucocorticoids and treatment responses

Effect of Low level laser on miniscrew displacement during canine retraction. (A randomized controlled clinical trial)

Background: Anchorage is an important consideration for successful orthodontic treatment. Skeletal anchorage by miniscrews provided better anchorage control then the ordinary extra-oral and intra-oral appliances. However, the stability of the miniscrews are still questionable since they might move under orthodontic loading. Objectives: The aim of this study was to evaluate the effect of low level laser on the miniscrew displacement when subjected to orthodontic force during canine retraction using CBCT. Methods: Twelve patients who required bilateral extraction of upper first premolar and absolute anchorage were recruited from the outpatient clinics of the Department of Orthodontics, Faculty of Dentistry, Beirut Arab University of age ranging 14-28 years. Twenty four miniscrews were assessed, two miniscrews were inserted into the buccal alveolar bone between the second premolar and first molar on the right and left side for each patient in a 60o oblique direction at the mucogingival junction to avoid root injury. They were divided into 2 sides; test side and a control side, the test side received 4 application of low-level laser therapy during the first twelve days of insertion with a 60 seconds for each application. While the control side did not receive any laser application. After waiting a period of twelve days from miniscrew insertion to allow for soft tissue healing, the upper right and left canines were retracted by 150g of nickel-titanium (NiTi) closed coil springs. A cone-beam computed tomography was taken to evaluate the miniscrew position before application of the force at baseline (T0) and after canine retraction at 6 months (T1). Results: There was no statistically significant difference of miniscrew head and tail displacements of the test side and a statistically significant difference of the heads for the control sides when compared to baseline. Conclusions: Miniscrews used in the current study with the suggested protocol underwent non-significant displacement when using low level laser. The miniscrews remained stable throughout the follow-up period (6 month) without any significant displacement on the test side

Microparticles as novel biomarkers/effectors in severe sepsis

Microparticles (MP) are submicron structures produced by all cells upon activation or apoptosis that act as a non-soluble means of communication between cells. They ferry proteins, bioactive lipids, RNA and receptors, as well as ridding cells of redundant organelles and toxins. They have been recently investigated for their pathophysiological role and as potential biomarkers/effectors in many diseases. In severe sepsis, studies of MP so far have produced inconsistent and even conflicting results. In this project, it was demonstrated that cell derived MP subsets vary according to the cause of severe sepsis (community acquired pneumonia (CAP) or faecal peritonitis (FP)), where CAP patients had higher levels of circulating MP. Surprisingly, FP patients MP levels were comparable to healthy volunteers. Further stratification of MP subsets according to their expression of the protein alpha-2-macroglobulin (A2M) has yielded better differentiation between the two diseases. The A2M expressing MP were significantly higher in survivors of community acquired pneumonia sepsis, but there was no similar association in patient with FP. Granulocyte macrophage colony-stimulating factor (GM-CSF) and interferon γ (IFN- γ) are being studied as possible adjuvant therapies in sepsis. They seem to reverse the immune-paresis that ensues after the initial insult. MP produced from whole blood stimulated with GM-CSF and IFN- γ were studied in this project. Both GM-CSF and IFN- γ increased MP expressing A2M over control. These MP elicited a pro-inflammatory phenotype when incubated with neutrophils or endothelial cells which may contribute to the potential benefits of GM-CSF and IFN- γ in severe sepsis.HCA internationa

Limited value and prohibitive risk of percutaneous coronary interventions in patients with advanced chronic kidney disease

AbstractObjectivesThis study sought to examine the immediate and short term outcome (6months) of percutaneous coronary interventions (PCIs) in patients with advanced chronic kidney disease (CKD).BackgroundPCI is established as a safe and effective option to treat patients with coronary artery disease. Difficulties and complications are known to be higher during PCI in patients with chronic kidney disease (CKD). Few data exist on the immediate and short term outcome of PCI in patients with advanced chronic kidney disease (creatinine clearance (Cr Cl) <30ml/min).Methods642 consecutive patients underwent PCIs. Patients were classified according to creatinine clearance into 3 groups. Group 1, Cr Cl >70, Group 2, Cr Cl <70 and >30, Group 3, Cr Cl <30. Group 1 included 332 (51.7%), group 2 included 292 patients (45.5%) and group 3 included 18 patients (2.8%). Immediate and short term follow-up (6months) was done for death, myocardial infarction, bleeding, TIA or cerebro-vascular stroke, contrast induced nephropathy (CIN) and repeated revascularization.ResultsAlthough immediate angiographic and procedural success was high (>93%) in all groups, as compared to patients in group 1 and 2, patients in group 3 had higher in-hospital morbidity (61% vs 0.9% and 8% for groups 3, 1 and 2 respectively P<0.0001, and mortality (5.6% vs 0.6% and 0.6% for groups 3, 1 and 2 respectively P<0.001) and short term, mortality was 28% vs 1.8% and 5.8% for in groups 3, 1 and 2 respectively, p<0.00002.ConclusionPCI for patient with advanced CKD carries a very high risk. It should be done on individual basis. Outcome is expected to be poor and short term benefit is expected to be limited

Assessment of Oxytocin Level in Patients with Manic Depressive Disorders

Background: Major depressive disorder (MDD) is a major health concern, with lifetime prevalence. In the United States estimated to be as high as 16.2%. Although, a number of pharmacological agents are available to treat, approximately 30–40% of patients do not respond to treatment. Therefore, a major emphasis in modern psychiatric research is to uncover the underlying etiology of mood disorders, and to develop novel efficacious antidepressant treatments. Oxytocinmay be of therapeutic benefit in these patients.Objective: To assess the level of oxytocin in patients with major depressive disorders.Patients and methods: A case-control study was conducted on sixty subjects above eighteen years old. They were classified into: 20 naïve patients during the manic attack of bipolar manic depressive disorder (group I), 20 naïve patients during the depressive attack of bipolar manic depressive disorder (group II) and 20 normal control subjects (group ІІІ). All participants were subjected to full history, clinical examination and laboratory measurement of oxytocin, AST, ALT, serum albumin, BUN &amp; creatinine.Results: On comparing group I (bipolar patients with recent attack of mania) and group 3 (control) regarding serum oxytocin level, there was a significant difference in serum oxytocin being higher in patients with manic symptoms (p &lt; 0.001) but with no significant difference between group 2 (bipolar patients with recent attack of depression) and group 3 (control).Conclusion: The significant difference in the level of oxytocin among the studied groups may suggest a possible role of oxytocin in management of patients with such psychiatric disorder