Why do we need ‘myth-busting’ in the study of Sino–African relations?

The literature on Sino–African relations has debated whether or not China's growing presence is a threat to Western or African interests, and has come to the conclusion that China's behavior is not uniquely immoral. Many countries, including Western liberal democracies, similarly give aid to local autocrats to secure natural resources. Why, then, has so much effort been made to come to this perhaps unsurprising conclusion? We argue that the literature on Chinese foreign policy remains heavily influenced by Western states' policy interests, resulting in an impoverished debate that is primarily concerned with the idea of a China threat. In order to recover the diversity in our research on Chinese foreign policy, we argue for the need to go beyond the confines of Western strategic interests

Stress responsive miR-23a attenuates skeletal muscle atrophy by targeting MAFbx /atrogin-1

Muscle atrophy occurs in many pathological states and results primarily from accelerated protein degradation by the ubiquitin-proteasome pathway. We used dexamethasone to induce muscle wasting and investigated the role of a microRNA (miRNA) in the control of muscle-specific E3 ubiquitin ligase MAFbx/atrogin-1. Here we show that miR-23a suppresses MAFbx/atrogin-1 translation by binding to 3'UTR of the mRNA. Furthermore, ectopic expression of miR-23a is sufficient to protect myocytes from atrophy in vitro and in vivo in response to dexamethasone treatment, and heat stress-induced miR-23a protects muscle from dexamethasone-induced muscle atrophy. Our surprising discovery of the physiological role of miR-23a in preventing the atrophy program should lay the basis not only for further understanding of the mechanisms of muscle wasting in diverse diseases, but also for developing novel therapies for these debilitating conditions