59 research outputs found
Hyperfine Spectroscopy of Optically Trapped Atoms
We perform spectroscopy on the hyperfine splitting of Rb atoms trapped
in far-off-resonance optical traps. The existence of a spatially dependent
shift in the energy levels is shown to induce an inherent dephasing effect,
which causes a broadening of the spectroscopic line and hence an inhomogeneous
loss of atomic coherence at a much faster rate than the homogeneous one caused
by spontaneous photon scattering. We present here a number of approaches for
reducing this inhomogeneous broadening, based on trap geometry, additional
laser fields, and novel microwave pulse sequences. We then show how hyperfine
spectroscopy can be used to study quantum dynamics of optically trapped atoms.Comment: Review/Tutoria
Models and algorithms for energy-efficient scheduling with immediate start of jobs
We study a scheduling model with speed scaling for machines and the immediate start requirement for jobs. Speed scaling improves the system performance, but incurs the energy cost. The immediate start condition implies that each job should be started exactly at its release time. Such a condition is typical for modern Cloud computing systems with abundant resources. We consider two cost functions, one that represents the quality of service and the other that corresponds to the cost of running. We demonstrate that the basic scheduling model to minimize the aggregated cost function with n jobs is solvable in O(nlogn) time in the single-machine case and in O(n²m) time in the case of m parallel machines. We also address additional features, e.g., the cost of job rejection or the cost of initiating a machine. In the case of a single machine, we present algorithms for minimizing one of the cost functions subject to an upper bound on the value of the other, as well as for finding a Pareto-optimal solution
Decomposition algorithms for submodular optimization with applications to parallel machine scheduling with controllable processing times
In this paper we present a decomposition algorithm for maximizing a linear function over a submodular polyhedron intersected with a box. Apart from this contribution to submodular optimization, our results extend the toolkit available in deterministic machine scheduling with controllable processing times. We demonstrate how this method can be applied to developing fast algorithms for minimizing total compression cost for preemptive schedules on parallel machines with respect to given release dates and a common deadline. Obtained scheduling algorithms are faster and easier to justify than those previously known in the scheduling literature
Anti-proliferative effect of Rosmarinus officinalis L. extract on human melanoma A375 cells
Rosemary (Rosmarinus officinalis L.) has been used since ancient times in traditional medicine, while nowadays various rosemary formulations are increasingly exploited by alternative medicine to cure or prevent a wide range of health disorders. Rosemary's bioproperties have prompted scientific investigation, which allowed us to ascertain antioxidant, anti-inflammatory, cytostatic, and cytotoxic activities of crude extracts or of pure components. Although there is a growing body of experimental work, information about rosemary's anticancer properties, such as chemoprotective or anti-proliferative effects on cancer cells, is very poor, especially concerning the mechanism of action. Melanoma is a skin tumor whose diffusion is rapidly increasing in the world and whose malignancy is reinforced by its high resistance to cytotoxic agents; hence the availability of new cytotoxic drugs would be very helpful to improve melanoma prognosis. Here we report on the effect of a rosemary hydroalcoholic extract on the viability of the human melanoma A375 cell line. Main components of rosemary extract were identified by liquid chromatography coupled to tandem mass spectrometry (LC/ESI-MS/MS) and the effect of the crude extract or of pure components on the proliferation of cancer cells was tested by MTT and Trypan blue assays. The effect on cell cycle was investigated by using flow cytometry, and the alteration of the cellular redox state was evaluated by intracellular ROS levels and protein carbonylation analysis. Furthermore, in order to get information about the molecular mechanisms of cytotoxicity, a comparative proteomic investigation was performed
Evolving pacing strategies for team pursuit track cycling
Team pursuit track cycling is a bicycle racing sport held on velodromes and
is part of the Summer Olympics. It involves the use of strategies to minimize
the overall time that a team of cyclists needs to complete a race. We present
an optimisation framework for team pursuit track cycling and show how to evolve
strategies using metaheuristics for this interesting real-world problem. Our
experimental results show that these heuristics lead to significantly better
strategies than state-of-art strategies that are currently used by teams of
cyclists.Markus Wagner, Jareth Day, Diora Jordan, Trent Kroeger, Frank Neumannhttp://www.springer.com/business+%26+management/operations+research/book/978-1-4614-6321-
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