1,292 research outputs found

    Color structure for soft gluon resummation - a general recipe

    Full text link
    A strategy for calculating the color structure needed for soft gluon resummation for processes with any number of colored partons is introduced using a N_c --> infinity inspired basis. In this basis a general formalism can be found at the same time as the calculations are simplified. The advantages are illustrated by recalculating the soft anomalous dimension matrix for the processes gg --> gg, q\qbar --> q \qbar g and q\qbar --> ggg.Comment: 16 page

    The pathogenesis of oral lichen planus

    Get PDF
    Both antigen-specific and non-specific mechanisms may be involved in the pathogenesis of oral lichen planus (OLP). Antigen-specific mechanisms in OLP include antigen presentation by basal keratinocytes and antigen-specific keratinocyte killing by CD8(+) cytotoxic T-cells. Non-specific mechanisms include mast cell degranulation and matrix metalloproteinase (MMP) activation in OLP lesions. These mechanisms may combine to cause T-cell accumulation in the superficial lamina propria, basement membrane disruption, intra-epithelial T-cell migration, and keratinocyte apoptosis in OLP. OLP chronicity may be due, in part, to deficient antigen-specific TGF-beta1-mediated immunosuppression. The normal oral mucosa may be an immune privileged site (similar to the eye, testis, and placenta), and breakdown of immune privilege could result in OLP and possibly other autoimmune oral mucosal diseases. Recent findings in mucocutaneous graft-versus-host disease, a clinical and histological correlate of lichen planus, suggest the involvement of TNF-alpha, CD40, Fas, MMPs, and mast cell degranulation in disease pathogenesis. Potential roles for oral Langerhans cells and the regional lymphatics in OLP lesion formation and chronicity are discussed. Carcinogenesis in OLP may be regulated by the integrated signal from various tumor inhibitors (TGF-beta1, TNF-alpha, IFN-gamma, IL-12) and promoters (MIF, MMP-9). We present our recent data implicating antigen-specific and non-specific mechanisms in the pathogenesis of OLP and propose a unifying hypothesis suggesting that both may be involved in lesion development. The initial event in OLP lesion formation and the factors that determine OLP susceptibility are unknown

    Dynamics of mitochondrial inheritance in the evolution of binary mating types and two sexes

    Get PDF
    The uniparental inheritance (UPI) of mitochondria is thought to explain the evolution of two mating types or even true sexes with anisogametes. However, the exact role of UPI is not clearly understood. Here, we develop a new model, which considers the spread of UPI mutants within a biparental inheritance (BPI) population. Our model explicitly considers mitochondrial mutation and selection in parallel with the spread of UPI mutants and self-incompatible mating types. In line with earlier work, we find that UPI improves fitness under mitochondrial mutation accumulation, selfish conflict and mitonuclear coadaptation. However, we find that as UPI increases in the population its relative fitness advantage diminishes in a frequency-dependent manner. The fitness benefits of UPI 'leak' into the biparentally reproducing part of the population through successive matings, limiting the spread of UPI. Critically, while this process favours some degree of UPI, it neither leads to the establishment of linked mating types nor the collapse of multiple mating types to two. Only when two mating types exist beforehand can associated UPI mutants spread to fixation under the pressure of high mitochondrial mutation rate, large mitochondrial population size and selfish mutants. Variation in these parameters could account for the range of UPI actually observed in nature, from strict UPI in some Chlamydomonas species to BPI in yeast. We conclude that UPI of mitochondria alone is unlikely to have driven the evolution of two mating types in unicellular eukaryotes

    Deuterated species in extragalactic star-forming regions

    Full text link
    We present a theoretical study of the deuterated species detectability in various types of extragalactic star-forming regions based on our predictions of chemical abundances. This work is motivated by the past and current attempts at observing deuterated species in external galaxies such as NGC~253, IC~342 and the LMC. Here, we investigate the influence of the density, the temperature, the FUV radiation field, the cosmic ray ionisation, and the metallicity on the fractional abundances and D/H abundance ratios of about 20 deuterated species. Without modelling any particular source, we determined how the deuterium chemistry behaves in different physical environments such as starburst, cosmic-rays enhanced environments, low metallicity and high redshift galaxies. In general, our predicted column densities seem in good agreement with those derived from the current limited dataset of observations in external galaxies. We provide, for the first time, a list of key deuterated species whose abundances are high enough to be possibly detectable by the Atacama Large Millimeter Array (ALMA) and Herschel, as a function of galactic nuclear activity and redshift.Comment: 19 pages, 6 figures, 5 tables, In press in Ap

    Improving NLO-parton shower matched simulations with higher order matrix elements

    Full text link
    In recent times the algorithms for the simulation of hadronic collisions have been subject to two substantial improvements: the inclusion, within parton showering, of exact higher order tree level matrix elements (MEPS) and, separately, next-to-leading order corrections (NLOPS). In this work we examine the key criteria to be met in merging the two approaches in such a way that the accuracy of both is preserved, in the framework of the POWHEG approach to NLOPS. We then ask to what extent these requirements may be fulfilled using existing simulations, without modifications. The result of this study is a pragmatic proposal for merging MEPS and NLOPS events to yield much improved MENLOPS event samples. We apply this method to W boson and top quark pair production. In both cases results for distributions within the remit of the NLO calculations exhibit no discernible changes with respect to the pure NLOPS prediction; conversely, those sensitive to the distribution of multiple hard jets assume, exactly, the form of the corresponding MEPS results.Comment: 38 pages, 17 figures. v2: added citations and brief discussion of related works, MENLOPS prescription localized in a subsection. v3: cited 4 more MEPS works in introduction

    Report of the QCD Working Group

    Get PDF
    The activities of the QCD working group concentrated on improving the understanding and Monte Carlo simulation of multi-jet final states due to hard QCD processes at LEP, i.e. quark-antiquark plus multi-gluon and/or secondary quark production, with particular emphasis on four-jet final states and b-quark mass effects. Specific topics covered are: relevant developments in the main event generators PYTHIA, HERWIG and ARIADNE; the new multi-jet generator APACIC++; description and tuning of inclusive (all-flavour) jet rates; quark mass effects in the three- and four-jet rates; mass, higher-order and hadronization effects in four-jet angular and shape distributions; b-quark fragmentation and gluon splitting into b-quarks.Comment: 95 pages, 48 figures, contribution to Proceedings of the LEP2 Monte Carlo Workshop. References for NLO 4-jet matrix elements adde

    Lines, Circles, Planes and Spheres

    Full text link
    Let SS be a set of nn points in R3\mathbb{R}^3, no three collinear and not all coplanar. If at most n−kn-k are coplanar and nn is sufficiently large, the total number of planes determined is at least 1+k(n−k2)−(k2)(n−k2)1 + k \binom{n-k}{2}-\binom{k}{2}(\frac{n-k}{2}). For similar conditions and sufficiently large nn, (inspired by the work of P. D. T. A. Elliott in \cite{Ell67}) we also show that the number of spheres determined by nn points is at least 1+(n−13)−t3orchard(n−1)1+\binom{n-1}{3}-t_3^{orchard}(n-1), and this bound is best possible under its hypothesis. (By t3orchard(n)t_3^{orchard}(n), we are denoting the maximum number of three-point lines attainable by a configuration of nn points, no four collinear, in the plane, i.e., the classic Orchard Problem.) New lower bounds are also given for both lines and circles.Comment: 37 page

    Simultaneous X-ray, gamma-ray, and Radio Observations of the repeating Fast Radio Burst FRB 121102

    Full text link
    We undertook coordinated campaigns with the Green Bank, Effelsberg, and Arecibo radio telescopes during Chandra X-ray Observatory and XMM-Newton observations of the repeating fast radio burst FRB 121102 to search for simultaneous radio and X-ray bursts. We find 12 radio bursts from FRB 121102 during 70 ks total of X-ray observations. We detect no X-ray photons at the times of radio bursts from FRB 121102 and further detect no X-ray bursts above the measured background at any time. We place a 5σ\sigma upper limit of 3×10−113\times10^{-11} erg cm−2^{-2} on the 0.5--10 keV fluence for X-ray bursts at the time of radio bursts for durations <700<700 ms, which corresponds to a burst energy of 4×10454\times10^{45} erg at the measured distance of FRB 121102. We also place limits on the 0.5--10 keV fluence of 5×10−105\times10^{-10} erg cm−2^{-2} and 1×10−91\times10^{-9} erg cm−2^{-2} for bursts emitted at any time during the XMM-Newton and Chandra observations, respectively, assuming a typical X-ray burst duration of 5 ms. We analyze data from the Fermi Gamma-ray Space Telescope Gamma-ray Burst Monitor and place a 5σ\sigma upper limit on the 10--100 keV fluence of 4×10−94\times10^{-9} erg cm−2^{-2} (5×10475\times10^{47} erg at the distance of FRB 121102) for gamma-ray bursts at the time of radio bursts. We also present a deep search for a persistent X-ray source using all of the X-ray observations taken to date and place a 5σ\sigma upper limit on the 0.5--10 keV flux of 4×10−154\times10^{-15} erg s−1^{-1} cm−2^{-2} (3×10413\times10^{41} erg~s−1^{-1} at the distance of FRB 121102). We discuss these non-detections in the context of the host environment of FRB 121102 and of possible sources of fast radio bursts in general.Comment: 13 pages, 5 figures, published in Ap
    • …
    corecore