Mary Douglas and Institutions

We provide reasons why researchers of business and management who are interested in how institutions are related to organization would want to read and use the work of Mary Douglas. One of the central problems about which management and organization theorists still debate is the extent to which the structure of institutions and organizations determines the agency afforded to individuals. We show how Douglas makes space for a treatment of institutions that avoids the usual retreat to methodological individualism that characterises these debates. This holds out the promise of reinvigorating organisational analysis in a manner that is in step with calls for focusing on organization as a way of life and with calls for revisiting the classics

"Alguien que me vigile": vigilancia, disciplina y el proceso laboral justo a tiempo

Se emplean la teoría y las observaciones para argumentar que los regímenes Justo a Tiempo (JAT)/Control Total de Calidad (CTC) crean y requieren sistemas de vigilancia, los cuales presentan mejoras respecto a regímenes previos al infundir disciplina, y por tanto, aumentar el control central. Dada su orientación teórica, este escrito se basa en el trabajo de Michel Foucault, especialmente en su concepción de poder/conocimiento, tal como se plantea en su libro Disciplina y castigo. Este soporte teórico se extiende para proporcionar un medio de análisis de los mecanismos de vigilancia y control que operan en el lugar de trabajo contemporáneo. Mientras se entiende que la responsabilidad táctica en una organización que practica el JAT/CTC es delegada, simultáneamente el control estratégico se centraliza; ésto representa una forma de degeneración. Basándonos en el trabajo de Foucault, argumentaremos que el enfoque JA T/CTC se facilita y se acentúa mediante la operación de dos fuerzas disciplinarias complementarias. La primera de ellas es la disciplina que se deriva del escrutinio de los propios compañeros en una celda de manufactura, círculo de calidad, etc., un proceso horizontal que es sustentado por la estructura organizacional asociada con los procesos JAT/CTC. La segunda fuerza disciplinaria clave es aquella que se deriva del uso de los cada vez más poderosos sistemas de información administrativos, los cuales suministran vigilancia extensiva a nivel de la planta, un proceso vertical que proporciona un mecanismo superior de control. Demostramos que los sistemas de vigilancia integrales de los procesos JAT/CTC están diseñados deliberadamente para establecer disciplina en la forma más eficiente y hacer posible un control minucioso con un mínimo de supervisores. El efecto deseado al enlazar estas fuerzas duales es minimizar las divergencias negativas del comportamiento esperado y de las normas administrativas definidas, mientras se identifican las divergencias positivas y se maximiza su potencial creativo

An evaluation of the fixed concentration procedure for assessment of acute inhalation toxicity

Acute inhalation studies are conducted in animals as part of chemical hazard identification and for classification and labelling. Current methods employ death as an endpoint (OECD TG403 and TG436) while the recently approved fixed concentration procedure (FCP) (OECD TG433) uses fewer animals and replaces lethality as an endpoint with evident toxicity. Evident toxicity is the presence of clinical signs that predict that exposure to the next highest concentration will cause severe toxicity or death in most animals. Approval of TG433 was the result of an international initiative, led by the National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs), which collected data from six laboratories on clinical signs recorded for inhalation studies on 172 substances. This paper summarises previously published data and describes the additional analyses of the dataset that were essential for approval of the TG

Investigating the effectiveness of the Mediterranean diet in pregnant women for the primary prevention of asthma and allergy in high-risk infants: protocol for a pilot randomised controlled trial

This research is funded by the Chief Scientist Office of The Scottish Government/Chief Medical Officer Directorate (Grant CZG/2/558). The authors would like to acknowledge the staff involved in the NHS ethical and research and development review processes, and staff at the Health Records Department of the Edinburgh Royal Infirmary for their help in getting the recruitment material to potential participants. The staff at the ultrasound/X-ray clinics at the two NHS Lothian sites where the participants are met by the researcher are most helpful and accommodating. The authors thank Anne Galloway (dietitian) who, when available, is delivering the intervention at one of the sites. They would also like to thank the participants for volunteering to take part, Dr Rob Elton the independent statistician, and Julia Clark (dietitian), Dr Ulugbek Nurmatov (researcher), and our Consumer Involvement Group for their input.Peer reviewedPublisher PD

Laboratory and Clinical Studies of Cardiac Transplantation

Cardiac transplantation was carried out on four patients at the Medical College of Virginia between May and October of 1968, in an effort to salvage them from the terminal stages of otherwise uncorrectable heart disease. Despite a strikingly good early recovery from operation in each case, three of the patients died of acute homograft rejection in one to three weeks; our second case is living and well, ten months after operation, and is at this writing the world\u27s third longest survivor. The world experience to June of 1969 includes about 130 cardiac transplants. Of the first 100 patients operated on over six months ago, 20 are surviving, and the majority of these have returned to a productive existence, demonstrating the feasibility of complete rehabilitation of at least some terminal patients after cardiac transplantation. The high mortality rate--significantly higher than was anticipated--has resulted from acute and chronic homograft rejection and from the equally difficult problem of infection. Certain lessons have been learned from our own experience and from the world experience with this procedure, and these will be reviewed in an attempt to establish the current status and future potential of cardiac transplantation

Australian rural adolescents’ experiences of accessing psychological help for a mental health problem

Objective: This study aims to explore Australian rural adolescents’ experiences of accessing help for a mental health problem in the context of their rural communities. Design and setting: A qualitative research design was used whereby university students who had sought help for a mental health problem during their adolescence were interviewed about their experiences. Interviews were conducted face-to-face at the university. Main outcome measures: A semi-structured interview schedule was designed around the study’s main research questions. Audio-taped interviews were transcribed and thematically coded using a constant comparative method. Participants: Participants were first-year undergraduate psychology students between the ages of 17 and 21 years who sought help for a mental health issue during their adolescence and who at that time resided in a rural area. Results: Participants highlighted various barriers to seeking help for mental health problems in the context of a rural community, including: social visibility, lack of anonymity, a culture of self-reliance, and social stigma of mental illness. Participants’ access to help was primarily school-based, and participants expressed a preference for supportive counselling over structured interventions. Characteristics of school-based helpers that made them approachable included: ‘caring’, ‘nonjudgemental’, ‘genuine’, ‘young’, and able to maintain confidentiality. Conclusions: The findings support previous research that reveals barriers to help seeking for mental health problems that are unique to the culture of rural communities. The study raises questions about the merit of delivery of primary mental health care to young people via GPs alone and suggests that school-based counsellors be considered as the first step in a young person’s access to mental health care.C

Consensus recommendations for the safe handling of cytotoxic agents in Cytotoxic Academic Research Laboratories (CARL)

Cytotoxic agents, also called antineoplastic agents, are used in cancer treatment due to their inherent activity to inhibit cell growth or proliferation, or DNA, RNA and protein synthesis. They are, therefore, hazardous by nature in a non-selective manner leading to disruption of cell growth and function of both diseased and healthy cells of treated patients. While the benefits of receiving cytotoxic agents may outweigh the incurred risks for patients, the same cannot be said for exposed healthcare practitioners involved in the transport, preparation, administration, and resulting waste disposal of these agents. Consequently, many professional bodies around the world have set standards of practice to prevent occupational exposure of healthcare workers to cytotoxic agents, and hospitals have been active in defining strict policies in this concern. However, due to the variability of the practice and infrastructure in academic settings, some activities performed within the cytotoxic academic research laboratory often do not adhere to recommendations published by guidelines. The present recommendations were therefore set forward by members of a working group who are experts on the subject matter representing academic, clinical, and research backgrounds in an attempt to promote safe cytotoxic handling in academic institutions. The document maps out the trajectory of cytotoxic agents being investigated in academic research laboratories while providing recommendations on the delivery, storage, use and disposal of cytotoxic agents in university settings

Predictors of starting and stopping chemsex in men who have sex with men in England: findings from the AURAH2 prospective study

BACKGROUND: Chemsex (the use of psychoactive drugs in sexual contexts) has been associated with HIV acquisition and other STIs, so there is benefit in identifying those most likely to start chemsex to offer risk reduction interventions such as pre-exposure prophylaxis (PrEP). To date, there have been no data from a longitudinal study analysing factors most associated with starting and stopping chemsex. METHODS: The prospective cohort study, Attitudes to and Understanding Risk of Acquisition of HIV over Time (AURAH2), collected 4 monthly and annual online questionnaire data from men who have sex with men (MSM) from 2015 to 2018. We investigate the association of sociodemographic factors, sexual behaviours and drug use with starting and stopping chemsex among 622 men who completed at least one follow-up questionnaire. Poisson models with generalised estimating equations were used to produce risk ratios (RRs) accounting for multiple starting or stopping episodes from the same individual. Multivariable analysis was adjusted for age group, ethnicity, sexual identity and university education. FINDINGS: In the multivariable analysis, the under 40 age group was significantly more likely to start chemsex by the next assessment (RR 1.79, 95% CI 1.12 to 2.86). Other factors which showed significant association with starting chemsex were unemployment (RR 2.10, 95% CI 1.02 to 4.35), smoking (RR 2.49, 95% CI 1.63 to 3.79), recent condomless sex (CLS), recent STI and postexposure prophylaxis (PEP) use in the past year (RR 2.10, 95% CI 1.33 to 3.30). Age over 40 (RR 0.71, 95% CI 0.51 to 0.99), CLS, and use of PEP (RR 0.64, 95% CI 0.47 to 0.86) and PrEP (RR 0.47, 95% CI 0.29 to 0.78) were associated with lower likelihood of stopping chemsex by the next assessment. INTERPRETATION: Knowledge of these results allows us to identify men most likely to start chemsex, thus providing an opportunity for sexual health services to intervene with a package of risk mitigation measures, especially PrEP use