868 research outputs found

    Finite difference lattice Boltzmann model with flux limiters for liquid-vapor systems

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    In this paper we apply a finite difference lattice Boltzmann model to study the phase separation in a two-dimensional liquid-vapor system. Spurious numerical effects in macroscopic equations are discussed and an appropriate numerical scheme involving flux limiter techniques is proposed to minimize them and guarantee a better numerical stability at very low viscosity. The phase separation kinetics is investigated and we find evidence of two different growth regimes depending on the value of the fluid viscosity as well as on the liquid-vapor ratio.Comment: 10 pages, 10 figures, to be published in Phys. Rev.

    Utjecaj različitih površinski aktivnih tvari i njihovih koncentracija na kontrolirano oslobađanje kaptoprila iz polimernih matriksa

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    Various methods are available to formulate water soluble drugs into sustained release dosage forms by retarding the dissolution rate. One of the methods used to control drug release and thereby prolong therapeutic activity is to use hydrophilic and lipophilic polymers. In this study, the effects of various polymers such as hydroxypropyl methylcellulose (HPMC), ethylcellulose (EC) and sodium carboxymethylcellulose (CMC) and surfactants (sodium lauryl sulphate, cetyltrimethylammonium bromide and Arlacel 60) on the release rate of captopril were investigated. The results showed that an increase in the amount of HPMC K15M resulted in reduction of the release rate of captopril from these matrices. When HPMC was partly replaced by NaCMC (the ratio of HPMC/NaCMC was 5:1), the release rate of the drug significantly decreased. However, there was no significant difference in release rate of captopril from matrices produced with ratios of 5:1 and 2:1 of HPMC/NaCMC. The presence of lactose in matrices containing HPMC and NaCMC increased the release rate of captopril. It was interesting to note that although partial replacement of HPMC by EC reduced the release rate of the drug (ratio of HPMC/EC 2:1), the release rate was increased when the ratio of HPMC/EC was reduced to 1:1. The effects of various surfactants on the release rate of captopril from HPMC/EC 1:1 matrices were also investigated. The results showed that the surfactants did not significantly change the release rate of the drug. Release data were examined kinetically and the ideal kinetic models were estimated for the drug release. The kinetic analysis of drug release data from various formulations showed that incorporation of surfactants in HPMC/EC matrices did not produce a zero-order release pattern.Postoje različite metode formuliranja vodotopljivih lijekova u dozirane ljekovite oblike s polaganim oslobađanjem. Jedan od načina postizanja kontroliranog otpuštanja, a prema tome i produljenog učinka je upotreba hidrofilnih i lipofilnih polimera. U ovom radu proučavan je utjecaj različitih polimera poput hidroksipropil metilceluloze (HPMC), etilceluloze (EC) i natrijeve soli karboksimetilceluloze (NaCMC) i površinski aktivnih tvari (natrijevog lauril-sulfata, cetiltrimetilamonijevog bromida i Arlacela 60) na oslobađanje kaptoprila. Rezultati pokazuju da povećanje količine HPMC K15M ima za posljedicu smanjenje oslobađanja kaptoprila iz matriksa. Ako se HPMC djelomično zamijeni s NaCMC (omjer HPMC/NaCMC 5:1), oslobađanje ljekovite tvari značajno se smanjuje. Međutim, nema značajne razlike u oslobađanju kaptoprila iz matriksa s omjerom HPMC/NaCMC 5:1 i 2:1. Prisutnost laktoze u matriksu koji sadrži HPMC i NaCMC povećalo je oslobađanje kaptoprila. Iako djelomična zamjena HPMC s EC smanjuje oslobađanje ljekovite tvari (omjer HPMC/EC 2:1), oslobađanje se povećava uz omjer HPMC/EC 1:1. Nadalje, ispitivan je utjecaj površinski aktivnih tvari na oslobađanje kaptoprila iz matriksa u kojima je omjer HPMC/EC (1:1). Može se zaključiti da površinski aktivne tvari ne utječu značajno na oslobađanje ljekovite tvari. U sklopu istraživanja određen je i kinetički model oslobađanja kaptoprila. Analiza kinetičkih podataka ukazuje da dodatak površinski aktivnih tvari u HPMC/EC matrikse ne slijedi kinetiku nultog reda

    Determination of some trace elements in nails from population nearby oil fields in Southern Iraq

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    Level of some trace elements Cadmium ( Cd), Cobalt (Co), Cupper (Cu),Nickel(Ni), Lead (Pb), and Zinc (Zn) in nails from 10 human being samples taken randomly from population nearby oil fields were examined from different subjects with respect to gender, age, smoking habit, the period of time living or working nearby the oil fields area and the health case were carried out using flame atomic absorption spectrophotometer (Sens AA GBC Scientific Equipment DUAL). Co showed the highest concentration (56.5

    Shocked molecular hydrogen towards the Tornado nebula

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    We present near-infrared and millimetre-line observations of the Tornado nebula (G357.7-0.1). We detected 2.12 micron_m H2 1-0 S(1) line emission towards the suspected site of interaction with a molecular cloud revealed by the presence of an OH(1720 MHz) maser. The distribution of the H2 emission is well correlated with the nonthermal radio continuum emission from the Tornado, and the velocity of the H2 emission spans over 100 km/s, which both imply that the H2 emission is shock excited. We also detected millimetre-lines from 12CO and 13CO transitions at the velocity of the maser, and mapped the distribution of the molecular cloud in a 2 x 2 arcmin^2 region around the maser. The peak of the molecular cloud aligns well with an indentation in the nebula's radio continuum distribution, suggesting that the nebula's shock is being decelerated at this location, which is consistent with the presence of the OH(1720 MHz) maser and shocked H2 emission at that location.Comment: 10 pages, 8 figures, minor changes, accepted to MNRA

    Determination of some trace elements in nails from population nearby oil fields in Southern Iraq

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    Level of some trace elements Cadmium ( Cd), Cobalt (Co), Cupper (Cu),Nickel(Ni), Lead (Pb), and Zinc (Zn) in nails from 10 human being samples taken randomly from population nearby oil fields were examined from different subjects with respect to gender, age, smoking habit, the period of time living or working nearby the oil fields area and the health case were carried out using flame atomic absorption spectrophotometer (Sens AA GBC Scientific Equipment DUAL). Co showed the highest concentration (56.58µg/g) while no level were reported for Cu (ND) . The levels of the Co, Zn, and Ni elements were statistically higher in male subjects (56.58, 42.03, and 8.99) µg/g compared to 26.72, 36.20, and 0.73 µg/g for female subjects while Pb showed the highest level in female  subjects 48.48 µg/g compared to 17.03 µg/g  in male subjects. high levels of trace elements were observed in non-smokers, compared to smokers. The highest level of trace elements were appeared to those who are between (20-40) years old and also who are living period of time limited between (8-21) years nearby the oil field areas . Occupationally exposure showed no effect for trace elements accumulation in human finger nails compared to the time living nearby the oil field area that was limited between (9-10) years. One of the voluntaries who have a health problem hypertension as his case showed a highest level for the Pb element compared with the other   hypertension case and the diabetes case, and the other voluntaries who have no health problems
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