Building the Holocene clinothem in the Gulf of Papua: An ocean circulation study

This paper investigates the role that tidal and wind-driven flows and buoyant river plumes play in the development of the Holocene clinothem in the Gulf of Papua. Time series data from bottom tripods and a mooring were obtained at four locations near the mouth of the Fly River during portions of 2003 and 2004. Flows in the Gulf of Papua during calendar year 2003 were hindcast every 3 h using the Navy Coastal Ocean Model (NCOM) with boundary conditions from the Navy Atmospheric Prediction System, the east Asian seas implementation of NCOM, and the OTIS Tidal Inversion System. Results show that tidal flows on the modern clinoform are strong and are landward and seaward directed. Peak spring tidal velocities can provide the shear stresses necessary to keep sediment up to sand size in motion as the wind-driven and baroclinic currents distribute it from the river mouths across and along the shelf in two circulation states. During the monsoon season, the clinoform topset is swept by a seaward surface flow and landward bottom flow, reflecting river plumes and coastal upwelling. Seaward, this structure evolves into a SW directed surface current over the clinothem foreset with accompanying landward directed near-bed currents that trend obliquely up the foreset to the WSW over much of the clinothem. During the trade wind season, the inner and outer topset are swept by NE directed, contour-parallel surface currents, underneath which lie obliquely landward near-bed currents. These modeled flows and complex gyres in shallow water coupled with wave- and current-supported gravity flows or river floods can explain the form, internal clinoform shapes, and mineralogy of the modern Gulf of Papua clinothem

Early lives: The late chalcolithic and early bronze age at Çadır höyük

Çadır Höyük, located in the Yozgat Province of the north-central Anatolian plateau, was continuously occupied from the late sixth millennium BCE until at least the thirteenth century CE. This article focuses on the fourth millennium BCE during which the Uruk System in southern Mesopotamia emerged, flourished and then retracted, and the Kura-Araxes culture from Transcaucasia ventured into Anatolia and the Levant. A close investigation of the Çadır settlement reveals a population that embraced the opportunities afforded it through the expanded trade and intercultural connections available during the millennium; the community transitioned into new socioeconomic patterns accompanied by changes in socioreligious and possibly sociopolitical behaviors. The disappearance of such opportunities at the end of the fourth millennium, rather than decimating a village that had come to rely on them, revealed the resilience of the community as it once again reoriented its focus to more local endeavors

Stability and change at Çadlr Höyük in central Anatolia: A case of Late Chalcolithic globalisation?

Scholars have recently investigated the efficacy of applying globalisation models to ancient cultures such as the fourth-millennium BC Mesopotamian Uruk system. Embedded within globalisation models is the 'complex connectivity' that brings disparate regions together into a singular world. In the fourth millennium BC, the site of Çadlr Höyük on the north-central Anatolian plateau experienced dramatic changes in its material culture and architectural assemblages, which in turn reflect new socio-economic, sociopolitical and ritual patterns at this rural agro-pastoral settlement. This study examines the complex connectivities of the ancient Uruk system, encompassing settlements in more consistent contact with the Uruk system such as Arslantepe in southeastern Anatolia, and how these may have fostered exchange networks that reached far beyond the Uruk 'global world' and onto the Anatolian plateau

Tourism and Economic Globalization: An Emerging Research Agenda

Globalization characterizes the economic, social, political, and cultural spheres of the modern world. Tourism has long been claimed as a crucial force shaping globalization, while in turn the developments of the tourism sector are under the influences of growing interdependence across the world. As globalization proceeds, destination countries have become more and more susceptible to local and global events. By linking the existing literature coherently, this study explores a number of themes on economic globalization in tourism. It attempts to identify the forces underpinning globalization and assess the implications on both the supply side and the demand side of the tourism sector. In view of a lack of quantitative evidence, future directions for empirical research have been suggested to investigate the interdependence of tourism demand, the convergence of tourism productivity, and the impact of global events

Differences in Efficacy and Safety of Pharmaceutical Treatments between Men and Women: An Umbrella Review

Being male or female is an important determinant of risks for certain diseases, patterns of illness and life expectancy. Although differences in risks for and prognoses of several diseases have been well documented, sex-based differences in responses to pharmaceutical treatments and accompanying risks of adverse events are less clear. The objective of this umbrella review was to determine whether clinically relevant differences in efficacy and safety of commonly prescribed medications exist between men and women. We retrieved all available systematic reviews of the Oregon Drug Effectiveness Review Project published before January 2010. Two persons independently reviewed each report to identify relevant studies. We dually abstracted data from the original publications into standardized forms. We synthesized the available evidence for each drug class and rated its quality applying the GRADE (Grading of Recommendations Assessment, Development and Evaluation) approach. Findings, based on 59 studies and data of more than 250,000 patients suggested that for the majority of drugs no substantial differences in efficacy and safety exist between men and women. Some clinically important exceptions, however, were apparent: women experienced substantially lower response rates with newer antiemetics than men (45% vs. 58%; relative risk 1.49, 95% confidence interval 1.35–1.64); men had higher rates of sexual dysfunction than women while on paroxetine for major depressive disorder; women discontinued lovastatin more frequently than men because of adverse events. Overall, for the majority of drugs sex does not appear to be a factor that has to be taken into consideration when choosing a drug treatment. The available body of evidence, however, was limited in quality and quantity, confining the range and certainty of our conclusions

EARLY LIVES The Late Chalcolithic and Early Bronze Age at Cadir Hoyuk

Cadir Hoyuk, located in the Yozgat Province of the north-central Anatolian plateau, was continuously occupied from the late sixth millennium BCE until at least the thirteenth century CE. This article focuses on the fourth millennium BCE during which the Uruk System in southern Mesopotamia emerged, flourished and then retracted, and the Kura-Araxes culture from Transcaucasia ventured into Anatolia and the Levant. A dose investigation of the cadir settlement reveals a population that embraced the opportunities afforded it through the expanded trade and intercultural connections available during the millennium; the community transitioned into new socioeconomic patterns accompanied by changes in socioreligious and possibly sociopolitical behaviors. The disappearance of such opportunities at the end of the fourth millennium, rather than decimating a village that had come to rely on them, revealed the resilience of the community as it once again reoriented its focus to more local endeavors

Stability and change at Çadır Höyük in central Anatolia: a case of Late Chalcolithic globalisation?

Scholars have recently investigated the efficacy of applying globalisation models to ancient cultures such as the fourth-millennium BC Mesopotamian Uruk system. Embedded within globalisation models is the 'complex connectivity' that brings disparate regions together into a singular world. In the fourth millennium BC, the site of cadir Hoyuk on the north-central Anatolian plateau experienced dramatic changes in its material culture and architectural assemblages, which in turn reflect new socio-economic, sociopolitical and ritual patterns at this rural agro-pastoral settlement. This study examines the complex connectivities of the ancient Uruk system, encompassing settlements in more consistent contact with the Uruk system such as Arslantepe in southeastern Anatolia, and how these may have fostered exchange networks that reached far beyond the Uruk 'global world' and onto the Anatolian plateau