Infectious Bovine Rhinotracheitis Virus Antibody Responses to Vaccines Used in Combination

The objective of this experimentation was to determine if circulating antibody titers to parainfluenza type-3 (PI-3) and infectious bovine rhinotracheitis (IBR) viruses could be enhanced by a combination of vaccines. The vaccines utilized were a modified live virus vaccine administered by the intranasal route and an inactivated virus vaccine injected intramuscularly. Virus neutralization tests were conducted on sera obtained at intervals before and following vaccination. Unfortunately, the calves were apparently exposed naturally to PI-3 virus, and the responses to that virus were inconclusive. However, antibody responses to IBR virus were dramatically enhanced by the combination of the two vaccines

Visualization at the mouse neuromuscular junction of a submembrane structure in common with Torpedo postsynaptic membranes

To test for submembrane structures common to postsynaptic membranes of muscle and electric tissue, mouse sternomastoid muscles were fixed in the presence of tannic acid under conditions such that a heavy layer of densely staining material was built up on plasma membranes. In this section electron micrographs of such muscles, the hydrophobic portion of the bilayer and some membrane-associated structures appear in strong negative contrast. At the endplate, acetylcholine receptor-rich membrane regions appear as a broad (14-15-nm) image approximately bisected by the thin (approximately 2-nm) image of the bilayer. The extracellular half of the image arises from the receptor protein. The cytoplasmic half contains a distinct bar of contrasted material which is precisely co-extensive with the receptor image Quantitative and direct visual comparisons show that the image is almost indistinguishable from that obtained by a similar method applied to isolated postsynaptic membranes from electric tissue of Torpedo californica (Sealock, R. (1982) J. Cell Biol. 92:514-522). In the latter case, the bar probably arises from the 43,000-dalton protein, a major peripheral membrane protein component of the isolated membranes. The results thus suggest that the 43,000-dalton protein in muscle and electric tissue forms similar structures and, conversely, that the structure in the isolated membranes retains the essential features of its in situ state

Antibody Responses of Young Calves to Inactivated Viral Vaccines

Three commercial inactivated virus vaccines were evaluated for immunogenicity in young calves with residual maternal antibodies. Groups of 30 calves were administered each of the vaccines at the start of the experimentation and were administered a second dose 32 days later. Serum was obtained from these calves and 30 calves in a nonvaccinated control group prior to vaccination and at 32, 61, 99 and 125 days thereafter. Antibody responses to viruses in two of the vaccines were extremely limited. The third vaccine overcame suppression by maternal antibodies and elicited responses clearly differentiated from antibody levels in the control group of calves

Effect of nuclear transparency from the (p,2p) measurements on 6Li and 12C at 1 GeV

We studied the production of protons to the backward direction in (p,2p) reactions on 6Li and 12C, accompanied by a proton emitted into the forward hemisphere. The momenta of the final two protons were measured in a wide range with the two-arm time-of-flight spectrometer. For each event we reconstructed the mass of the intermediate off-shell particles. We have discovered a strong narrow dip in the mass spectra of intermediate mesons at the mass of the real pion.Comment: 24 pages,11 figure

Flute Recital: Deanna Sealock, Flute; John Frame, Piano; Pamela Wilcox, Soprano; May 23, 1971

Centennial Recital HallMay 23, 19718:15 p.m

Use of Risk Factors to Alter Management for Reduction of Neonatal Calf Diarrhea Incidence

Risk factors associated with calf diarrhea were identified and management strategies were developed to reduce the impact of these risk factors on the incidence of disease. Five hundred forty-one females were bred to calve between March 3 and May 15, 1998. Risk factors identified included: parity, the different origin of the groups of cattle, weather, poor body condition score, and intensity of calving. These cattle were forty-six percent first calf heifers, the remainder of the cattle were mature cows. The heifers were from five different sources, and the mature cows were from the ISU Rhodes farm. The groups had never been commingled. The body condition scores of the cattle averaged below five, and there was a high maintenance requirement because of muddy conditions and frequent wet hair coats due to the continuing rains. Two hundred of the heifers were bred to calve in twenty-six days, and the first one hundred ninety-five cows were due to calve in a total of thirty days. Procedures were developed to allow a one-way flow of the cow/calf pairs through calving areas to reduce the contact of the calves with possible large numbers of pathogens and separate first parity heifers from the mature cows

Nuclear Response in Electron Scattering at High Momentum Transfer

The nuclear response functions for high energy electron scattering were calculated in the wide region of excitation energy. The three typical regions were studied: the quasi-elastic region, the $\Delta$-excitation region and the intermediate region where the meson-exchange currents give significant contribution. In the quasi-elastic and the $\Delta$ regions the response functions were found for finite size nucleus with account of relativistic kinematics. The contribution of the meson-exchange currents was calculated in the relativistic Fermi-gas model. The results were compared with the electron scattering data at high momentum transfer from $^{12}C$ and $^{16}O$.Comment: 21 pages, LaTeX, 8 figures (uses epsf-style), submitted to Nucl. Phys.