3,376 research outputs found

    But the Spirit Himself Intercedes : An Exegetical on Romans 8:26-27

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    In two short verses, Paul communicates the deep dependency a believer must have on the Holy Spirit to be sustained through this age, specifically on the topic of prayer. The aim of this thesis is to give a fuller approach to the interpretation of Romans 8:26-27. Many sources have contributed to the interpretation of this passage and the purpose of this thesis is to bring together many of those contributions to shed light on the meaning of Paul’s words and produce an insightful and cohesive reading of the passage. The thesis will explore an array of material, including an analysis of the Greek text of Romans 8:26-27 in order to interpret the passage in light of its original context

    Creating synergy with boundary chains: Can they improve usability of climate information?

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    AbstractBoundary organizations facilitate and negotiate the interface between science production and use to improve information usability particularly for climate adaptation. To support the increasing demand for usable climate information and enable adaptation, boundary organizations themselves must innovate to foster more efficient production of usable science and more effective networks of producers and users. A recent innovation centers on the idea of boundary chains, whereby boundary organizations work together to increase efficiencies such as leveraging human and social resources. While this idea holds promise, more work is needed to better understand how and why boundary organizations work together to improve information usability and other beneficial outcomes. In this perspective for the special issue, we propose a new conceptual framework for exploring why and how boundary chains form and for evaluating whether or not they are successful. We then apply the framework to case studies that are discussed in more detail in this special issue. Our framework hinges on the notion that boundary chains that are successful are those that create synergy. In turn, synergy depends on a combination of complementarity, putting two kinds of inputs together results in greater output than either each engaging partner could deliver on their own, and embeddedness, the choices and actions on one side are at least partially influenced by and dependent upon the choices and actions of the other side and vice versa

    Narrowing the gap between climate science and adaptation action: The role of boundary chains

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    AbstractBoundary organizations play a critical role at the interface between science and decision making. They create, protect and sustain an interactive space for co-production of science and decision-making while simultaneously bridging the two domains. In this special issue we advance the concept of boundary chains, whereby two or more boundary organizations link together synergistically to influence one another and to leverage each other’s resources and strengths to achieve shared goals. In this process both the level of complementary and embeddedness between these organizations is critical for achieving these goals. Through a series of case studies focusing primarily but not exclusively on climate information use in the United States, we aim to advance scholarship in the field by examining innovation among boundary organizations and testing the boundary chain concept. In doing so, we focus on boundary chains both as a theoretical construct to re-think the structure, function, and adaptability of boundary organizations and as a practical strategy to further increase the usability of climate knowledge for adaptation action across a wider range of users

    Maternal Psychiatric Disease and Epigenetic Evidence Suggest a Common Biology for Poor Fetal Growth

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    We sought to identify and characterize predictors of poor fetal growth among variables extracted from perinatal medical records to gain insight into potential etiologic mechanisms. In this process we reevaluated a previously observed association between poor fetal growth and maternal psychiatric disease. We evaluated 449 deliveries of \u3e36 weeks gestation that occurred between 9/2008 and 9/2010 at the Women and Infants Hospital in Providence Rhode Island. This study group was oversampled for Small-for-Gestational-Age (SGA) infants and excluded Large-for-Gestational-Age (LGA) infants. We assessed the associations between recorded clinical variables and impaired fetal growth: SGA or Intrauterine Growth Restriction (IUGR) diagnosis. After validating the previously observed association between maternal psychiatric disease and impaired fetal growth we addressed weaknesses in the prior studies by explicitly considering antidepressant use and the timing of symptoms with respect to pregnancy. We then evaluated DNA methylation levels at 27 candidate loci in placenta from a subset of these deliveries (n = 197) to examine if epigenetic variation could provide insight into the mechanisms that cause this co-morbidity

    Development of the multilingual semantic annotation system

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    This paper reports on our research to generate multilingual semantic lexical resources and develop multilingual semantic annotation software, which assigns each word in running text to a semantic category based on a lexical semantic classification scheme. Such tools have an important role in developing intelligent multilingual NLP, text mining and ICT systems. In this work, we aim to extend an existing English semantic annotation tool to cover a range of languages, namely Italian, Chinese and Brazilian Portuguese, by bootstrapping new semantic lexical resources via automatically translating existing English semantic lexicons into these languages. We used a set of bilingual dictionaries and word lists for this purpose. In our experiment, with minor manual improvement of the automatically generated semantic lexicons, the prototype tools based on the new lexicons achieved an average lexical coverage of 79.86% and an average annotation precision of 71.42% (if only precise annotations are considered) or 84.64% (if partially correct annotations are included) on the three languages. Our experiment demonstrates that it is feasible to rapidly develop prototype semantic annotation tools for new languages by automatically bootstrapping new semantic lexicons based on existing ones

    OPRM1 rs1799971 Genotype Predicts Drinking Behavior in Males, but Not Females

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    • The prevalence of alcohol disorders costs Americans $223.5 billion yearly due mostly from losses in workplace productivity, as well as health care and criminal justice expenses (CDC, 2016). • Maximum number of drinks consumed in a 24 hour period is a valid indicator of dangerous drinking behavior and may reflect an increased tolerance for high levels of alcohol (Edenberg, 2016). • Awareness of factors related to such heavy drinking is important for targeting interventions for dangerous alcohol use. • Men drink significantly more than women, with about 4.5% of men and 2.5% of women meeting the diagnostic criteria for alcohol dependence in 2013 (Wilsnack, et al., 2000), (Esser et al., 2014). • Alcoholism is highly heritable and the endogenous opioid system has been shown to play a vital role in alcohol and other drug dependencies (Miranda et al., 2010). • The mu-opioid receptor gene (OPRM1) is involved in a variety of pathological conditions, such as alcohol use disorder (AUD). The polymorphism has been shown to modulate sensitivity to alcohol (Bart, et al., 2005), (Sauriyal et al., 2011), (Mauge and Blendy, 2010). • Carriers of the G allele for rs1799971, a polymorphism of OPRM1, result in an amino acid change at position 40 of the mu opioid receptor, and express receptors with 3 times higher affinity to Β-endorphins, and this has been associated with an increased risk for substance and alcohol dependence (Miranda et al., 2010), (Zhang, et al., 2005). • There is more social pressure on females to abstain from alcohol use, so it is possible that this effect will be weaker for females due to the competing effect of social pressure (Nolen-Hoeksema, 2004). • We hypothesize that individuals with at least one G allele will have a higher number of maximum drinks consumed within 24 hours than A homozygotes. • We expect this effect to be stronger in males than in females. • We also expect that males will drink more than females

    OPRM1 rs1799971 Genotype Predicts Drinking Behavior in Males, but Not Females

    Get PDF
    • The prevalence of alcohol disorders costs Americans $223.5 billion yearly due mostly from losses in workplace productivity, as well as health care and criminal justice expenses (CDC, 2016). • Maximum number of drinks consumed in a 24 hour period is a valid indicator of dangerous drinking behavior and may reflect an increased tolerance for high levels of alcohol (Edenberg, 2016). • Awareness of factors related to such heavy drinking is important for targeting interventions for dangerous alcohol use. • Men drink significantly more than women, with about 4.5% of men and 2.5% of women meeting the diagnostic criteria for alcohol dependence in 2013 (Wilsnack, et al., 2000), (Esser et al., 2014). • Alcoholism is highly heritable and the endogenous opioid system has been shown to play a vital role in alcohol and other drug dependencies (Miranda et al., 2010). • The mu-opioid receptor gene (OPRM1) is involved in a variety of pathological conditions, such as alcohol use disorder (AUD). The polymorphism has been shown to modulate sensitivity to alcohol (Bart, et al., 2005), (Sauriyal et al., 2011), (Mauge and Blendy, 2010). • Carriers of the G allele for rs1799971, a polymorphism of OPRM1, result in an amino acid change at position 40 of the mu opioid receptor, and express receptors with 3 times higher affinity to Β-endorphins, and this has been associated with an increased risk for substance and alcohol dependence (Miranda et al., 2010), (Zhang, et al., 2005). • There is more social pressure on females to abstain from alcohol use, so it is possible that this effect will be weaker for females due to the competing effect of social pressure (Nolen-Hoeksema, 2004). • We hypothesize that individuals with at least one G allele will have a higher number of maximum drinks consumed within 24 hours than A homozygotes. • We expect this effect to be stronger in males than in females. • We also expect that males will drink more than females

    An Innovation Diffusion Approach to Examining the Adoption of Social Media by Small Businesses: an Australian Case Study

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    Whilst many studies have examined social media use from a consumer perspective, relatively few have examined its use by small and medium sized enterprises (SMEs), a group for whom it is becoming increasingly important. This study aims to provide a deeper understanding of an under-researched area, the experience of SMEs during the process of adopting social media, by identifying the factors that influence SMEs to either adopt social media or not and, if they adopt it, how they use it and evaluate its usefulness. The study involves analysis of in-depth interviews with 42 Australian businesses. Roger’s innovation decision process is used in an innovative manner to classify SMEs into five key stages of adoption of social media and identify the factors that influence the progression of SMEs across the various stages of adoption. The results show that the story of social media use is richer than just whether SMEs adopt it or not. Most participants used Facebook, suggesting it has become the de facto platform of choice to engage with social media. However, opinions of its perceived usefulness for SMEs varied widely across users. There was confusion surrounding the role of Twitter, its value, and concern about the amount of time needed to use it. YouTube was used by some SMEs to showcase their products or services. The study contributes to the literature by identifying key facilitators which appear critical to the decision by SMEs to continue use of social media – namely increased sales; brand development and a feeling of pressure that they ‘have to be there’. It also identifies some inhibitors to sustained use by SMEs, typically a lack of compatibility to industry sector; insufficient followership; and limited return on investment compared to effort required. Finally, the study shows how SMEs differentiate between social media platforms. Available at: https://aisel.aisnet.org/pajais/vol9/iss3/2

    Co-inquiry with students: When shared questions lead the way

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    Co-inquiry represents a distinctive relational model for partnering with students in SoTL that focuses on the process of seeking itself, and in particular, the importance of shared questions. We use case studies from two institutions to illustrate co-inquiry in action and highlight the importance of shared questions in changing the faculty-student dynamic in ways that foster deep learning. Clarifying the nature of co-inquiry around shared questions represents a valuable way to effectively strengthen and enrich learning not only for students, but also for everyone involved in SoTL partnerships with students. The programs described here illustrate how co-inquiry can work as a form of institutional SoTL, providing valuable and authentic opportunities to incorporate student voices—and shared questions—in effecting institutional change

    \u3ci\u3eTadaridanema delicatus\u3c/i\u3e (Schwartz, 1927) n. gen., n. comb. (Trichostrongylina: Molineidae) Parasite of Molossidae Bats

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    On the basis of the revision of the type material of Anoplostrongylus delicatus Schwartz, 1927, and new specimens collected from Tadarida brasiliensis mexicana (Saussure, 1860) in 4 arid localities from Mexico, we describe a new genus (Tadaridanema n. gen.), to which A. delicatus is transferred (as Tadaridanema delicatus (Schwartz, 1927) n. gen., n. comb.). This new genus differs from all other genera included in noplostrongylinae by having ray 2 larger than ray 3. In addition, T. delicatus can be differentiated from the type species of Anoplostrongylus (Anoplostrongylus paradoxus (Travassos, 1918)) because it possess vestibular branches equal in length, cephalic inflation divided into 2 regions, and synlophe with many small ridges at the midbody level, whereas in T. delicatus, vestibular branches are equal in size, cephalic inflation is simple in structure, and the synlophe has only 2 well-developed dorsal cuticular ridges
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