The impact of contact effort on mode-specific selection and measurement bias

In 2011, a large-scale mixed-mode experiment was linked to the Crime Victimisation Survey (CVS). This experiment consisted of a randomized allocation of sample persons to the four contemporary survey modes Web, mail, telephone and face-to-face, and a follow-up using only interviewer modes. The aim of the experiment was to disentangle mode-specific selection- and measurement bias. In a previous paper (Schouten et al 2013), mode-specific selection and measurement biases were reported for a large number of key variables from the CVS and the Labour Force Survey. This paper is a follow-up to that study and investigates the size of the selection and measurement biases as a function of contact effort, where contact effort refers to the number of telephone calls, the number of face-to-face visits and the number of reminders in Web and mail. In the analyses, face-to-face response based on a maximum of six visits, the default face-to-face strategy at Statistics Netherlands, is used as the benchmark. The analyses show that contact effort has little impact on the size of measurement bias and a modest impact on the size of selection bias. From the results, it is therefore concluded that contact effort is not a strong common cause of nonresponse and measurement error

Understanding Willingness to Share Smartphone-Sensor Data

The growing smartphone penetration and the integration of smartphones into people’s everyday practices offer researchers opportunities to augment survey measurement with smartphone-sensor measurement or to replace self-reports. Potential benefits include lower measurement error, a widening of research questions, collection of in situ data, and a lowered respondent burden. However, privacy considerations and other concerns may lead to nonparticipation. To date, little is known about the mechanisms of willingness to share sensor data by the general population, and no evidence is available concerning the stability of willingness. The present study focuses on survey respondents’ willingness to share data collected using smartphone sensors (GPS, camera, and wearables) in a probability-based online panel of the general population of the Netherlands. A randomized experiment varied study sponsor, framing of the request, the emphasis on control over the data collection process, and assurance of privacy and confidentiality. Respondents were asked repeatedly about their willingness to share the data collected using smartphone sensors, with varying periods before the second request. Willingness to participate in sensor-based data collection varied by the type of sensor, study sponsor, order of the request, respondent’s familiarity with the device, previous experience with participating in research involving smartphone sensors, and privacy concerns. Willingness increased when respondents were asked repeatedly and varied by sensor and task. The timing of the repeated request, one month or six months after the initial request, did not have a significant effect on willingness

Maximum interpolable gap length in missing smartphone-based GPS mobility data

Passively-generated location data have the potential to augment mobility and transportation research, as demonstrated by a decade of research. A common trait of these data is a high proportion of missingness. Naïve handling, including list-wise deletion of subjects or days, or linear interpolation across time gaps, has the potential to bias summary results. On the other hand, it is unfeasible to collect mobility data at frequencies high enough to reflect all possible movements. In this paper, we describe the relationship between the temporal and spatial aspects of these data gaps, and illustrate the impact on measures of interest in the field of mobility. We propose a method to deal with missing location data that combines a so-called top-down ratio segmentation method with simple linear interpolation. The linear interpolation imputes missing data. The segmentation method transforms the set of location points to a series of lines, called segments. The method is designed for relatively short gaps, but is evaluated also for longer gaps. We study the effect of our imputation method for the duration of missing data using a completely observed subset of observations from the 2018 Statistics Netherlands travel study. We find that long gaps demonstrate greater downward bias on travel distance, movement events and radius of gyration as compared to shorter but more frequent gaps. When the missingness is unrelated to travel behavior, total sparsity can reach levels of up to 20% with gap lengths of up to 10 min while maintaining a maximum 5% downward bias in the metrics of interest. Temporal aspects can increase these limits; sparsity occurring in the evening or night hours is less biasing due to fewer travel behaviors

Testing the Effects of Automated Navigation in a General Population Web Survey

This study investigates how an auto-forward design, where respondents navigate through a web survey automatically, affects response times and navigation behavior in a long mixed-device web survey. We embedded an experiment in a health survey administered to the general population in The Netherlands to test the auto-forward design against a manual-forward design. Analyses are based on detailed paradata that keep track of the respondents’ behavior in navigating the survey. We find that an auto-forward design decreases comple­tion times and that questions on pages with automated navigation are answered significant­ly faster compared to questions on pages with manual navigation. However, we also find that respondents use the navigation buttons more in the auto-forward condition compared to the manual-forward condition, largely canceling out the reduction in survey duration. Furthermore, we also find that the answer options 'I don't know' and 'I rather not say' are used just as often in the auto-forward condition as in the manual-forward condition, indi­cating no differences in satisficing behavior. We conclude that auto-forwarding can be used to reduce completing times, but we also advice to carefully consider mixing manual and auto-forwarding within a survey

Data Collection Expert Prior Elicitation in Survey Design: Two Case Studies

Data collection staff involved in sampling designs, monitoring and analysis of surveys often have a good sense of the response rate that can be expected in a survey, even when this survey is new or done at a relatively low frequency. They make expectations of response rates, and, subsequently, costs on an almost continuous basis. Rarely, however, are these expectations formally structured. Furthermore, the expectations usually are point estimates without any assessment of precision or uncertainty. In recent years, the interest in adaptive survey designs has increased. These designs lean heavily on accurate estimates of response rates and costs. In order to account for inaccurate estimates, a Bayesian analysis of survey design parameters is very sensible. The combination of strong intrinsic knowledge of data collection staff and a Bayesian analysis is a natural next step. In this article, prior elicitation is developed for design parameters with the help of data collection staff. The elicitation is applied to two case studies in which surveys underwent a major redesign and direct historic survey data was unavailable

Smart cities, social media platforms and security: online content regulation as a site of controversy and conflict

Abstract Smart, technologically managed city-regions are one of the main characteristics of the contemporary world. Since the attack to the Charlie Hebdo offices, city-regions and social media digital technologies have increasingly been changing the definition of 'territory of security' and 'security governance'. What are the characteristics of the security architecture created by the interaction of smart city-regions and digital technologies? Drawing from Actor-Network theory and Science and Technology Studies, we provide an empirical account of the shape of this new territory, by presenting a study of the controversy concerning security and social media in UK, the role of cities in this changed security space, and how social sciences can help better understand and respond to the opportunities and threats of smart cities

Metal-macrofauna interactions determine microbial community structure and function in copper contaminated sediments

Peer reviewedPublisher PD

Effect of tissue-harvesting site on yield of stem cells derived from adipose tissue: implications for cell-based therapies

The stromal vascular fraction (SVF) of adipose tissue contains an abundant population of multipotent adipose-tissue-derived stem cells (ASCs) that possess the capacity to differentiate into cells of the mesodermal lineage in vitro. For cell-based therapies, an advantageous approach would be to harvest these SVF cells and give them back to the patient within a single surgical procedure, thereby avoiding lengthy and costly in vitro culturing steps. However, this requires SVF-isolates to contain sufficient ASCs capable of differentiating into the desired cell lineage. We have investigated whether the yield and function of ASCs are affected by the anatomical sites most frequently used for harvesting adipose tissue: the abdomen and hip/thigh region. The frequency of ASCs in the SVF of adipose tissue from the abdomen and hip/thigh region was determined in limiting dilution and colony-forming unit (CFU) assays. The capacity of these ASCs to differentiate into the chondrogenic and osteogenic pathways was investigated by quantitative real-time polymerase chain reaction and (immuno)histochemistry. A significant difference (P = 0.0009) was seen in ASC frequency but not in the absolute number of nucleated cells between adipose tissue harvested from the abdomen (5.1 ± 1.1%, mean ± SEM) and hip/thigh region (1.2 ± 0.7%). However, within the CFUs derived from both tissues, the frequency of CFUs having osteogenic differentiation potential was the same. When cultured, homogeneous cell populations were obtained with similar growth kinetics and phenotype. No differences were detected in differentiation capacity between ASCs from both tissue-harvesting sites. We conclude that the yield of ASCs, but not the total amount of nucleated cells per volume or the ASC proliferation and differentiation capacities, are dependent on the tissue-harvesting site. The abdomen seems to be preferable to the hip/thigh region for harvesting adipose tissue, in particular when considering SVF cells for stem-cell-based therapies in one-step surgical procedures for skeletal tissue engineering

Cisgenesis and intragenesis as new strategies for crop improvement

Cisgenesis and intragenesis are emerging plant breeding technologies which offer great promise for future acceptance of genetically engineered crops. The techniques employ traditional genetic engineering methods but are confined to transferring of genes and genetic elements between sexually compatible species that can breed naturally. One of the main requirements is the absence of selectable marker genes (such as antibiotic resistance genes) in the genome. Hence the sensitive issues with regard to transfer of foreign genes and antibiotic resistance are overcome. It is a targeted technique involving specific locus; therefore, linkage drag that prolongs the time for crop improvement in traditional breeding does not occur. It has great potential for crop improvement using superior alleles that exist in the untapped germplasm or wild species. Cisgenic and intragenic plants may not face the same stringent regulatory assessment for field release as transgenic plants which is a clear added advantage that would save time. In this chapter, the concepts of cis/intragenesis and the prerequisites for the development of cis/intragenesis plants are elaborated. Strategies for marker gene removal after selection of transformants are discussed based on the few recent reports from various plant species

Optimizing the diagnostic work-up of acute uncomplicated urinary tract infections

<p>Abstract</p> <p>Background</p> <p>Most diagnostic tests for acute uncomplicated urinary tract infections (UTIs) have been previously studied in so-called single-test evaluations. In practice, however, clinicians use more than one test in the diagnostic work-up. Since test results carry overlapping information, results from single-test studies may be confounded. The primary objective of the Amsterdam Cystitis/Urinary Tract Infection Study (ACUTIS) is to determine the (additional) diagnostic value of relevant tests from patient history and laboratory investigations, taking into account their mutual dependencies. Consequently, after suitable validation, an easy to use, multivariable diagnostic rule (clinical index) will be derived.</p> <p>Methods</p> <p>Women who contact their GP with painful and/or frequent micturition undergo a series of possibly relevant tests, consisting of patient history questions and laboratory investigations. Using urine culture as the reference standard, two multivariable models (diagnostic indices) will be generated: a model which assumes that patients attend the GP surgery and a model based on telephone contact only. Models will be made more robust using the bootstrap. Discrimination will be visualized in high resolution histograms of the posterior UTI probabilities and summarized as 5^th, 10^th, 25^th50^th, 75^th, 90^th, and 95^thcentiles of these, Brier score and the area under the receiver operating characteristics curve (ROC) with 95% confidence intervals. Using the regression coefficients of the independent diagnostic indicators, a diagnostic rule will be derived, consisting of an efficient set of tests and their diagnostic values.</p> <p>The course of the presenting complaints is studied using 7-day patient diaries. To learn more about the natural history of UTIs, patients will be offered the opportunity to postpone the use of antibiotics.</p> <p>Discussion</p> <p>We expect that our diagnostic rule will allow efficient diagnosis of UTIs, necessitating the collection of diagnostic indicators with proven added value. GPs may use the rule (preferably after suitable validation) to estimate UTI probabilities for women with different combinations of test results. Finally, in a subcohort, an attempt is made to identify which indicators (including antibiotic treatment) are useful to prognosticate recovery from painful and/or frequent micturition.</p