181 research outputs found

    Sjogren's syndrome: apoptosis by anti-SSA and anti-SSB antibodies

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    The pathogenesis of the Sjogren's Syndrome (SjS) has not yet been completely defined. However, the cell-mediated immunity plays an important role and the apoptosis of the ductal and acinar epithelial cells is responsible of the glandular tissue damage, through the cytotoxic T-cells, particularly of the CD4+ subpopulation, by the release of proteases (such as perforin and granzyme B) and by the interaction of the Fas Ligand (FasL; CD95L) of the T-lymphocytes, with the Fas (Apo-1; CD95) of the epithelial cells. The apoptotic death of the epithelial cells is the autocrine Fas/FasL interaction also. The anti-SSA and anti-SSB antibodies are the immunological markers of the Sjogren's syndrome, but it is not yet understood if they have pathogenetic implications...

    Induced responses to the wheat pathogen: Tan Spot—(Pyrenophora tritici-repentis) in wheat (Triticum aestivum) focus on changes in defence associated and sugar metabolism.

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    The study aimed to characterise the flag-leaf metabolomes of two spring wheat cultivars (Triticum aestivum L. cv. PF 080719 [PF] and cv. Fundacep Horizonte [FH]) following challenge with Ptr to gain insights into TS disease development.First online: 31 January 2024

    Linha do tempo da pesquisa com cevada cervejeira no Brasil.

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    Cronologia da pesquisa com cevada cervejeira no Brasil; Principais cultivares de cevada registradas no período de 1960 a 2022, no Ministério da Agricultura e Pecuária; Aspectos do melhoramento de cevada cervejeiraODS 2
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