Privacy Management of Multi User Environment in Online Social Networks (OSNs)

Online Social Networks (OSNs) are inherently designed to enable people to share personal and public information and make social connections with others. These OSNs provides digital social interactions and social as well as personal information sharing, but in sharing a number of security and privacy problems raised. While OSNs allow users to restrict access to shared data, they currently do not provide any mechanism to totally enforce privacy issue solver associated with multiple users. To this end, we propose an approach to enable the protection of shared data associated with multiple users in OSNs. We formulate an access control model to capture the essence of multiparty authorization requirements, along with a multiparty policy specification scheme and a policy enforcement mechanism. Besides we also implement a proof-of-concept prototype which is called as MController (multi controller) having contributor, stakeholder and disseminator controllers along with owner controller

Synthesis of 1-butoxy-4-tert-butylbenzene under The Effect of Multi-site Phase Transfer Catalysis System – A Kinetic Study

Phase transfer catalysis technique proved to be a useful method for synthesizing various organic compounds under heterogeneous reactions and recognized as a viable environmentally friendly. The influence of a new multi site phase transfer catalyst (MPTC) is the synthesis of 1-butoxy-4-tertbutylbenzene from 4-tert-butylphenol with 1-bromobutane (BB) under heterogeneous solid-liquid condition using potassium hydroxide as a base at 60 °C. The higher conversion of 1-bromobutane was achieved by using the synergistic condition of multi-site phase transfer catalyst in better efficacy. The reaction rate enhanced by decreases the volume of water. The apparent the reaction rate was found to be pseudo-first order kinetics. The apparent rate constant was increased linearly with the increase in the concentration of various parameters, such as: MPTC, temperature, potassium hydroxide, and stirring speed. The activation energy (Ea) was also calculated through the Arrhenius plot. Copyright © 2020 by Authors, Published by BCREC Group. This is an open access article under the CC BY-SA License (https://creativecommons.org/licenses/by-sa/4.0).

On Double Fuzzy M-open Mappings and Double Fuzzy M-closed Mappings

We introduce and investigate some new class of mappings called double fuzzy M-open map and double fuzzy M-closed map in double fuzzy topological spaces. Also, some of their fundamental properties are studied. Moreover, we investigate the relationships between double fuzzy open, double fuzzy θ semiopen, double fuzzy δ preopen, double fuzzy M open and double fuzzy e open and their respective closed mappings

Bioanalytical Method Development and Validation of Esomeprazole in Human Plasma by Lc-Ms/Ms.

This studies to measure Bioavailability and/or establish Bioequivalence of a product are important elements in support of orally administered drug products in investigational new drug applications (INDs), new drug applications (NDAs) , abbreviated new drug applications (ANDAs), and their supplements. The systemic exposure profile determined during clinical trials in the IND period can serve as a benchmark for subsequent BE studies. Until recently, bioavailability (rate and extent of absorption of medicaments from drug delivery systems) of drugs was not emphasized. It was more or less assumed that if the physical and chemical integrities of a drug product were assured pharmacologic performance would be observed. It is now recognized that formulation factors can influence the biologic availability of a medicament from a dosage unit in mammalian systems. Consequently, it has become common practice to establish bioavailability by measurement of blood levels of drugs following administration of dosage forms. However, it should be noted that either bioavailability or bioequivalence data could be generated without analytical methodology to accurately measure drugs in biological fluids. Currently there is a need in the pharmaceutical environment to develop analytical methods for the determination of Esomeprazole in human plasma. The developed method could then be applied to clinical trials to obtain accurate pharmacokinetic parameters in human plasma. HPLC-UV and LC-MS/MS methods have been reported. Some of these methods use complicated extraction equipments, long and tedious extraction procedures, and large amounts of solvents or biological fluids for extraction while other methods have a long turn around time during analysis. Esomeprazole is a proton pump inhibitor which reduces gastric acid secretion through inhibition of H+/K+-ATPase in gastric parietal cells. By inhibiting the functioning of this enzyme, the drug prevents formation of gastric acid. The bioanalytical methodology described in this manuscript was specific, sensitive, accurate and precise. The method employed HPLC coupled with electrospray ionization mass spectrometric detection (LC-ESI-MS). The method involved a simple sample preparation by liquid- liquid extraction followed by isocratic chromatographic separations. A sensitive method that is precise and accurate over a linear assay range of 5.000 – 1000.000 ng/mL has been validated for the determination of Esomeprazole in Human plasma using LC-MS/MS Method. The LC-ESI-MS method was capable of estimating 5 ng/ml of Esomeprazole accurately in human plasma with high degree of reproducibility.The method can be useful for further BA/BE studies Pharmacokinetic studies

Ethnomedicinal importance of fern and fern allies traditionally used by tribal people of Palani Hills (Kodaikanal), Western Ghats, South India

Numerous studies have focused on the medicinal properties of angiosperms; however, only limited amountof studies have explored the medicinal potentials of fern and fern allies. The present study focuses on theethnomedicinal values of fern and fern allies that are traditionally used by the tribal people of Palani hills in SouthIndia through a survey of the area. In the present study, information on 50 species belonging to 35 genera in19 families were recorded for their medicinal values with their botanical name, family, habitat, and manner ofusing recipes have been recorded

Physico-chemical characteristics of textile effluent collected from Erode, Pallipalayam and Bhavani polluted regions, Tamilnadu, India

Present study perceives that textile dye effluents of Erode, Pallipalayam and Bhavani region have substantial volume of EC, pH, TDS, COD, BOD, Sodium Chloride, Calcium, Magnesium, Potassium and heavy metals. Results point out that irrespective of the source, effluent properties exceeded permissible limits by WHO/ FAO/Federal Environmental Protection Agency for irrigation. The textile industry consumes a mixture of chemicals and huge amount of water during the production process. About 200 L of water are used to produce 1 kg of textile. The textile effluent can cause several health infections like haemorrhage, ulceration of skin, nausea, skin irritation and dermatitis

(R1965) Some More Properties on Generalized Double Fuzzy Z Alpha Open Sets

In this paper, a new class of sets termed as double fuzzy generalized Z alpha closed sets and double fuzzy generalized Z alpha open sets are introduced with the help of double fuzzy Z alpha open and double fuzzy Z alpha closed sets, respectively. Using these sets double fuzzy generalized Z alpha border, double fuzzy generalized Z alpha exterior and double fuzzy generalized Z alpha frontier of a fuzzy set in double fuzzy topological spaces are introduced. Also, the topological properties and characterizations of these sets and operators are studied. Furthermore, suitable examples have been provided to illustrate the theory

Biological investigations of ruthenium(III) 3-(Benzothiazol-2-liminomethyl)-phenol Schiff base complexes bearing PPh3 / AsPh3 coligand

New ruthenium(III) complexes with 3-(Benzothiazol-2-yliminomethyl)-phenol (HL) ligand have been synthesized and characterized with the aid of elemental analysis, IR, electronic, and electron paramagnetic resonance spectroscopic techniques. The binding mode of the ligand and complexes with DNA and their ability to bind DNA have been investigated by UV-vis absorption titration. In addition, the ligand and complexes have been subjected to antioxidant activity tests which showed that HL and its ruthenium(III) complexes possess significant scavenging effect against DPPH and OH radicals. Cytotoxic activities of the ligand and ruthenium(III) complexes showed that the ruthenium(III) complexes exhibited more effective cytotoxic activity against HeLa and MCF-7 cells than the corresponding ligand