12 research outputs found
SYMPTOM SEVERITY IN SCHIZOPHRENIA PATIENTS WITH NPAS3, DYSBINDIN-1 AND/OR TRIOBP PROTEIN PATHOLOGY IN THEIR BLOOD SERUM: A PANSS-BASED FOLLOW UP STUDY
Background: It has been proposed that aggregation of specific proteins in the brain may be a pathological element in schizophrenia
and other chronic disorders. Multiple such aggregating proteins have now been implicated through post mortem investigation,
including NPAS3 (Neuronal PAS domain protein 3), dysbindin-1 (encoded by the DTNBP1, Dystrobrevin Binding Protein 1, gene)
and TRIOBP (Trio-Binding Protein, multiple isoforms). While the presence of protein aggregates in the brain is interesting in terms of
understanding pathology, it is impractical as a biomarker. These proteins were therefore investigated recently in blood serum of schizophrenia
patients and controls, showing patients to have higher levels of NPAS3 in their serum generally. TRIOBP-1 and dysbindin-1
were also found in an insoluble state, implying aggregation, but did not clearly corresponding to disease state.
Subject and methods: We revisit 47 of the originally recruited 50 patients with schizophrenia, all of whom are Croatian and
aged between 18 and 72. We assessed their symptom specificity and severity using PANSS (the Positive and Negative Symptoms Scale),
comparing those with NPAS3, insoluble dysbindin-1 and/or insoluble TRIOBP-1 in their blood serum to those lacking any such protein
dysregulation.
Results: The frequency of each individual potential protein pathology among these patients was too low for meaningful statistical
analysis, however the 11 patients that displayed one or more of these pathologies (NPAS3, dysbindin-1, TRIOBP-1 and/or TRIOBP-
5/6) showed a subtle but significant increase in total PANSS scores compared to the 36 patients displaying none of the pathologies
(p = 0.031), seemingly driven principally by increased scores on the general psychopathology scale.
Conclusion: While the numbers of patients involved do not allow firm conclusions to be drawn at this time, this provides the first
indication that disturbed proteostasis in blood serum, of proteins that aggregate in the brains of schizophrenia patients, may correlate
with the severity of schizophrenia symptoms
SATISFACTION WITH LIFE AND COPING SKILLS IN THE ACUTE AND CHRONIC URTICARIA
Background: The purpose of this study was to examine the differences in satisfaction with life and coping strategies between
patients with acute and chronic urticaria.
Subjects and methods: Sixty patients with urticaria were divided into 2 groups after 6 weeks of standardized dermatology
treatment (33 patients with acute and 27 patients with chronic urticaria). At baseline, all patients answered the following
questionnaires: Satisfaction with Life Scale (SWLS), Personal Wellbeing Index (PWI-A), The Multidimensional Coping Inventory
(COPE) and General questionnaire (age, gender, education, employment, marital status). After six weeks all the participants were
re-tested with 2 questionnaires: SWLS and PWI-A.
Results: Six weeks after the initial testing there was a statistically significant difference in satisfaction with life between patients
with acute and chronic urticaria. Patients with acute urticaria were more satisfied with their lives than patients with chronic
urticaria. Also, there was a statistically significant difference in the use of emotion-focused coping, seeking social support for
emotional reasons and seeking social support for instrumental reasons. Patients with acute urticaria used emotion-focused coping
and sought social support for emotional and instrumental reasons to a greater degree than patients with chronic urticaria.
Conclusion: Patients with acute urticaria were more satisfied with their lives than patients with chronic urticaria. Patients with
acute urticaria used emotion-focused coping and sought social support for emotional and instrumental reasons to a greater degree
than patients with chronic urticaria
Intensive psychiatric care ā psychiatric emergencies
Intenzivna psihijatrijska skrb jest vrsta psihijatrijskog lijeÄenja bolesnika koja se provodi
na zatvorenom psihijatrijskom odjelu i po moguÄnosti u jedinici intenzivnog lijeÄenja, a
sadržaji su joj dijagnostika, lijeÄenje i opservacija hitnih stanja, odnosno bolesnika u psihijatriji.
UkljuÄuje sveobuhvatnu razinu skrbi, 24-satnu opservaciju te moguÄnost fiziÄkog sputavanja
i odvajanja bolesnika u sluÄaju gubitka kapaciteta za samokontrolu. NajÄeÅ”Äa hitna stanja
koja zahtijevaju intenzivnu psihijatrijsku skrb jesu suicidalnost, auto i hetero agresivnost
i krizna stanja. Pregled bolesnika ukljuÄuje anamnezu, heteroanamnezu, opis psihijatrijskog
statusa, opÄi somatski i neuroloÅ”ki pregled, laboratorijske pretrage, a ponekad CT i MRI mozga.
U lijeÄenju hitnog psihijatrijskog bolesnika upotrebljavaju se psihofarmakoterapija, psihoterapija
(kratka, individualna dinamski orijentirana, ventilacija, debriefing, suportivna psihoterapija
i obiteljska), te ponekad fiziÄko sputavanje i odvajanje bolesnika u izolacijsku
prostoriju zbog moguÄe opasnosti za sebe i/ili okolinu. Älanovi medicinskog tima su psihijatri
te medicinske sestre i tehniÄari koji su struÄno i posebno educirani u kliniÄkoj hitnoj psihijatriji
i koji Äe odmah po prijamu bolesnika odrediti prioritete postupaka, dijagnostike i lijeÄenja.
Vrijeme provedeno u jedinici za intenzivnu psihijatrijsku skrb razliÄito je, ali najÄeÅ”Äe je
od 2 do 6 dana. Po smirivanju akutne kliniÄke slike koja je i bila razlogom prijama u takvu jedinicu,
bolesnika se premjeÅ”ta na odgovarajuÄi psihijatrijski odjel sukladno njegovom opÄem
psihofiziÄkom stanju i psihijatrijskoj dijagnozi. Iako se opÄenito misli da su postupci intenzivne
psihijatrijske skrbi ponekad naglaÅ”eno specifiÄni ili izvan okvira kompetencija osoblja koje
radi u tim jedinicama, one su nužne i medicinski opravdane.Intensive psychiatric care is a type of psychiatric treatment of patients conducted in
a closed psychiatric ward, and engages the diagnosis and treatment of psychiatric emergencies.
Includes a comprehensive level of care, 24-hour observation, and the possibility of physical
restraint and isolation of patients in the event of loss of capacity for self-control. Psychiatric
disorders treated in such departments are deteriorating mental state within the various mental
disorders. The most common emergencies that require intensive psychiatric care are suicide,
auto and hetero aggressiveness and states of crisis. Examination of the patient includes
medical history, heteroanamnesis, description of psychiatric status, general and neurological
examination, laboratory tests, and sometimes CT and MRI of the brain. In order to take care of
urgent psychiatric patients in use is pharmacotherapy, psychotherapy (brief, individual dynamically
oriented, ventilation, debriefing, supportive and family psychotherapy), and sometimes
physical restraint and isolation of patients in isolation room because of possible danger to
himself and / or the environment. The principal members of the medical team are psychiatrists,
nurses and technicians who are highly qualified and trained in clinical psychiatry emergency
and will immediately determine procedure, diagnosis and treatment of the patient.
Time spent in psychiatric intensive care unit varies, but is usually from 2-6 days. By calming the
acute clinical picture which is the reason for admission to such department, the patient is
transferred to other psychiatric wards in accordance with its general mental and physical condition
and psychiatric diagnosis. Although it is generally thought that the procedures for intensive
psychiatric care is sometimes too hard or beyond the competence of personnel working
in such departments, they are medically necessary and justified
Intensive psychiatric care ā psychiatric emergencies
Intenzivna psihijatrijska skrb jest vrsta psihijatrijskog lijeÄenja bolesnika koja se provodi
na zatvorenom psihijatrijskom odjelu i po moguÄnosti u jedinici intenzivnog lijeÄenja, a
sadržaji su joj dijagnostika, lijeÄenje i opservacija hitnih stanja, odnosno bolesnika u psihijatriji.
UkljuÄuje sveobuhvatnu razinu skrbi, 24-satnu opservaciju te moguÄnost fiziÄkog sputavanja
i odvajanja bolesnika u sluÄaju gubitka kapaciteta za samokontrolu. NajÄeÅ”Äa hitna stanja
koja zahtijevaju intenzivnu psihijatrijsku skrb jesu suicidalnost, auto i hetero agresivnost
i krizna stanja. Pregled bolesnika ukljuÄuje anamnezu, heteroanamnezu, opis psihijatrijskog
statusa, opÄi somatski i neuroloÅ”ki pregled, laboratorijske pretrage, a ponekad CT i MRI mozga.
U lijeÄenju hitnog psihijatrijskog bolesnika upotrebljavaju se psihofarmakoterapija, psihoterapija
(kratka, individualna dinamski orijentirana, ventilacija, debriefing, suportivna psihoterapija
i obiteljska), te ponekad fiziÄko sputavanje i odvajanje bolesnika u izolacijsku
prostoriju zbog moguÄe opasnosti za sebe i/ili okolinu. Älanovi medicinskog tima su psihijatri
te medicinske sestre i tehniÄari koji su struÄno i posebno educirani u kliniÄkoj hitnoj psihijatriji
i koji Äe odmah po prijamu bolesnika odrediti prioritete postupaka, dijagnostike i lijeÄenja.
Vrijeme provedeno u jedinici za intenzivnu psihijatrijsku skrb razliÄito je, ali najÄeÅ”Äe je
od 2 do 6 dana. Po smirivanju akutne kliniÄke slike koja je i bila razlogom prijama u takvu jedinicu,
bolesnika se premjeÅ”ta na odgovarajuÄi psihijatrijski odjel sukladno njegovom opÄem
psihofiziÄkom stanju i psihijatrijskoj dijagnozi. Iako se opÄenito misli da su postupci intenzivne
psihijatrijske skrbi ponekad naglaÅ”eno specifiÄni ili izvan okvira kompetencija osoblja koje
radi u tim jedinicama, one su nužne i medicinski opravdane.Intensive psychiatric care is a type of psychiatric treatment of patients conducted in
a closed psychiatric ward, and engages the diagnosis and treatment of psychiatric emergencies.
Includes a comprehensive level of care, 24-hour observation, and the possibility of physical
restraint and isolation of patients in the event of loss of capacity for self-control. Psychiatric
disorders treated in such departments are deteriorating mental state within the various mental
disorders. The most common emergencies that require intensive psychiatric care are suicide,
auto and hetero aggressiveness and states of crisis. Examination of the patient includes
medical history, heteroanamnesis, description of psychiatric status, general and neurological
examination, laboratory tests, and sometimes CT and MRI of the brain. In order to take care of
urgent psychiatric patients in use is pharmacotherapy, psychotherapy (brief, individual dynamically
oriented, ventilation, debriefing, supportive and family psychotherapy), and sometimes
physical restraint and isolation of patients in isolation room because of possible danger to
himself and / or the environment. The principal members of the medical team are psychiatrists,
nurses and technicians who are highly qualified and trained in clinical psychiatry emergency
and will immediately determine procedure, diagnosis and treatment of the patient.
Time spent in psychiatric intensive care unit varies, but is usually from 2-6 days. By calming the
acute clinical picture which is the reason for admission to such department, the patient is
transferred to other psychiatric wards in accordance with its general mental and physical condition
and psychiatric diagnosis. Although it is generally thought that the procedures for intensive
psychiatric care is sometimes too hard or beyond the competence of personnel working
in such departments, they are medically necessary and justified
SYMPTOMS OF AGITATED DEPRESSION AND/OR AKATHISIA
Akathisia is a syndrome characterized by the unpleasant sensation of āinnerā restlessness that manifests itself in the inability of
sitting still or not moving. Many types of medicaments can cause akathisia as an adverse event of their use and they include:
antipsychotics, antidepressants, antiemetics, antihistamines, and psychoactive substances.
We will present the case of a 50 year old patient, treated on two occasions for psychotic depression. During the second
hospitalization it is possible that antipsychotic treatment combined with an antidepressant caused akathisia or there were symptoms
of agitated depression and akathisia present at the same time, which is very difficult to determine in everyday clinical practice.
We can conclude that in this case, as in many others, akathisia as a possible adverse effect of psychopharmacs was very hard to
identify. Therefore, it is necessary to have akathisia in mind when using certain medicaments, especially when combining several
that use the same enzymatic system and consequently raise levels of at least one of them
The role of psychosocial factors in development of urticaria : doctoral thesis
Koža zauzima specijalno mjesto u psihijatriji obzirom da se putem nje iskazuju razliÄite emocije kao Å”to su ljutnja, strah, sram i druge. Koža igra važnu ulogu i u procesu socijalizacije koji poÄinje u djetinjstvu i nastavlja se do odrasle dobi. Povezanost kože i mozga oÄituje se i u njihovom zajedniÄkom ektodermalnom podrijetlu, a odreÄeni su i zajedniÄkim hormonskim i neurotransmiterskim sustavom.
Cilj ovog rada bio je ispitati razlike izmeÄu ispitanika s akutnom i kroniÄnom urtikarijom u zadovoljstvu životom, strategijama suoÄavanja, crtama liÄnosti, anksioznosti, depresiji i percipiranom stresu. Ispitano je sto pedeset (150) ispitanika koji boluju od urtikarije a koji su podijeljeni u 2 skupine nakon 6 tjedana standardiziranog dermatoloÅ”kog lijeÄenja (88 akutnih i 62 kroniÄna ispitanika). U poÄetku su svi ispitanici ispunjavali slijedeÄe upitnike: upitnik kvalitete života -SWES, upitnik osobnog zadovoljstva životom-PWI-A, upitnik suoÄavanja sa stresom -COPE, Beckov inventar depresivnsoti -BDI, ljestvica za mjerenje anskioznosti kao trenutnog stanja i kao crte liÄnosti -STAI, skalu percepcije stresa - PSS, Eysenckov upitnik liÄnosti -EPQ i opÄi upitnik - dob, spol, obrazovanje, zapoÅ”ljavanje, braÄni i roditeljski status. Nakon Å”est tjedana svi sudionici su ponovno testirani s 2 upitnika: kvaliteta života i skala osobnog zadovoljstva. Dobiveni rezultati ukazuju da su ispitanici s akutnom urtikarijom zadovoljniji životom od bolesnika s kroniÄnom urtikarijom nakon 6 tjedana. Ispitanici s akutnom urtikarijom viÅ”e koriste emocijama usmjereno suoÄavanje, pozitivnu reinterpretaciju i rast liÄnosti, potiskivanje drugih aktivnosti od ispitanika s kroniÄnom urtikarijom, te traže socijalnu podrÅ”ku iz emocionalnih i instrumentalnih razloga u veÄoj mjeri od ispitanika s kroniÄnom urtikarijom. Ispitanici s kroniÄnom urtikarijom u manjoj mjeri koriste ventiliranje emocija i mentalni dezangažman od ispitanika s akutnom urtikarijom. VeÄi neuroticizam kod ispitanika s akutnom urtikarijom rezultira ÄeÅ”Äim koriÅ”tenjem problemu i emocijama usmjerenog suoÄavanja, te izbjegavanja. ViÅ”i nivo anksioznosti kao stanja u ispitanika s akutnom urtikarijom dovodi do koriÅ”tenja emocijama usmjerenog suoÄavanja i izbjegavanja. VeÄi neuroticizam kod ispitanika s kroniÄnom urtikarijom rezultira ÄeÅ”Äim koriÅ”tenjem izbjegavanja. ViÅ”i nivo anksioznosti kao stanja i crte liÄnosti u ispitanika s kroniÄnom urtikarijom dovodi do ÄeÅ”Äeg koriÅ”tenja izbjegavanja. ViÅ”a razina neuroticizma i anksioznosti (kao crte liÄnosti i kao stanja) kod pacijenata s akutnom i kroniÄnom urtikarijom, rezultira depresivnoÅ”Äu, dovodi do veÄe percepcije stresa i ÄeÅ”Äeg koriÅ”tenje izbjegavanja.
Na osnovu dobivenih rezultata treba istaÄi potrebu intredisciplinarnog pristupa u lijeÄenju urtikarije, koji bi ukljuÄivao i aktivnu ulogu psihijatra u lijeÄenju iste, a u cilju redukcije kronifikacije smetnji kako bi se poboljÅ”ala kvaliteta života ovih pacijenata te pomoglo bolesnicima u razvijanju adekvatnih strategija suoÄavanja koje bi im omoguÄile bolje noÅ”enje sa boleÅ”Äu.Skin occupies a special place in psychiatry because it express different emotions such as anger, fear, shame, and others. The skin plays an important role in the socialization process that begins in childhood and continues to adulthood. The link between the skin and the brain is also reflected in their common ectodermal origin, and common hormonal and neurotransmitter systems.
The purpose of this study was to examine the differences between acute and chronic urticaria subjects in satisfaction with life, coping strategies, personality traits, anxiety, depression and perception of stress One hundred and fifty (150) subjects with urticaria were divided into 2 groups after 6 weeks of standardized dermatology treatment (88 acute and 62 chronic urticaria subjects). At baseline, all subjects answered the following questionnaires: Satisfaction with Life Scale-SWLS, Personal Wellbeing Index-PWI-A, The Multidimensional Coping Inventory ā COPE, Beck Depression inventory-BDI, State trait Anxiety Inventory -STAI, Perception of stress scale-PSS, Eysenck Personality Questionnaire - EPQ and General questionnaire - age, gender, education, employment, marital and parental status. After six weeks all the participants were re-tested with 2 questionnaires: Satisfaction with life scale and Personal wellbeing index. Subjects with acute urticaria are more satisfied with their lives than patients with chronic urticaria after 6 weeks. Participants with acute urticaria largely used emotion-focused coping, positive reinterpretation and growth, supression of competing activities than patients with chronic urticaria. Subjects with acute urticaria seek social support for emotional issues and for the instrumental reason to a greater degree than patients with chronic urticaria. Subjects with chronic urticaria use venting of emotions and mental disengagement to a lesser degree than subjects with acute urticaria.
The higher neuroticism in subjects with acute urticaria is, the greater is using problem-focused coping, emotion-focused coping and avoidance. A higher level of anxiety as a state in participants with acute urticaria leads to use of emotion-focused coping and avoidance. The higher neuroticism in subjects with chronic urticaria results in frequent use of avoidance. A higher level of anxiety as a state and personality trait in participants with chronic urticaria leads to more frequent use of avoidance. Higher levels of neuroticism and anxiety (as a personality trait and as a condition) in patients with acute and chronic urticaria, results in higher depression, greater perception of stress and frequent use of avoidance.
Based on the obtained results, there is a need for interdisciplinary approach in the treatment of urticaria, which would include the active role of the psychiatrist in the treatment, with the aim of reduction of chronification of the disorder in order to improve the quality of life of those patients, and also to help patients to develop appropriate coping strategies that would enable them to better cope with the disease
The role of psychosocial factors in development of urticaria : doctoral thesis
Koža zauzima specijalno mjesto u psihijatriji obzirom da se putem nje iskazuju razliÄite emocije kao Å”to su ljutnja, strah, sram i druge. Koža igra važnu ulogu i u procesu socijalizacije koji poÄinje u djetinjstvu i nastavlja se do odrasle dobi. Povezanost kože i mozga oÄituje se i u njihovom zajedniÄkom ektodermalnom podrijetlu, a odreÄeni su i zajedniÄkim hormonskim i neurotransmiterskim sustavom.
Cilj ovog rada bio je ispitati razlike izmeÄu ispitanika s akutnom i kroniÄnom urtikarijom u zadovoljstvu životom, strategijama suoÄavanja, crtama liÄnosti, anksioznosti, depresiji i percipiranom stresu. Ispitano je sto pedeset (150) ispitanika koji boluju od urtikarije a koji su podijeljeni u 2 skupine nakon 6 tjedana standardiziranog dermatoloÅ”kog lijeÄenja (88 akutnih i 62 kroniÄna ispitanika). U poÄetku su svi ispitanici ispunjavali slijedeÄe upitnike: upitnik kvalitete života -SWES, upitnik osobnog zadovoljstva životom-PWI-A, upitnik suoÄavanja sa stresom -COPE, Beckov inventar depresivnsoti -BDI, ljestvica za mjerenje anskioznosti kao trenutnog stanja i kao crte liÄnosti -STAI, skalu percepcije stresa - PSS, Eysenckov upitnik liÄnosti -EPQ i opÄi upitnik - dob, spol, obrazovanje, zapoÅ”ljavanje, braÄni i roditeljski status. Nakon Å”est tjedana svi sudionici su ponovno testirani s 2 upitnika: kvaliteta života i skala osobnog zadovoljstva. Dobiveni rezultati ukazuju da su ispitanici s akutnom urtikarijom zadovoljniji životom od bolesnika s kroniÄnom urtikarijom nakon 6 tjedana. Ispitanici s akutnom urtikarijom viÅ”e koriste emocijama usmjereno suoÄavanje, pozitivnu reinterpretaciju i rast liÄnosti, potiskivanje drugih aktivnosti od ispitanika s kroniÄnom urtikarijom, te traže socijalnu podrÅ”ku iz emocionalnih i instrumentalnih razloga u veÄoj mjeri od ispitanika s kroniÄnom urtikarijom. Ispitanici s kroniÄnom urtikarijom u manjoj mjeri koriste ventiliranje emocija i mentalni dezangažman od ispitanika s akutnom urtikarijom. VeÄi neuroticizam kod ispitanika s akutnom urtikarijom rezultira ÄeÅ”Äim koriÅ”tenjem problemu i emocijama usmjerenog suoÄavanja, te izbjegavanja. ViÅ”i nivo anksioznosti kao stanja u ispitanika s akutnom urtikarijom dovodi do koriÅ”tenja emocijama usmjerenog suoÄavanja i izbjegavanja. VeÄi neuroticizam kod ispitanika s kroniÄnom urtikarijom rezultira ÄeÅ”Äim koriÅ”tenjem izbjegavanja. ViÅ”i nivo anksioznosti kao stanja i crte liÄnosti u ispitanika s kroniÄnom urtikarijom dovodi do ÄeÅ”Äeg koriÅ”tenja izbjegavanja. ViÅ”a razina neuroticizma i anksioznosti (kao crte liÄnosti i kao stanja) kod pacijenata s akutnom i kroniÄnom urtikarijom, rezultira depresivnoÅ”Äu, dovodi do veÄe percepcije stresa i ÄeÅ”Äeg koriÅ”tenje izbjegavanja.
Na osnovu dobivenih rezultata treba istaÄi potrebu intredisciplinarnog pristupa u lijeÄenju urtikarije, koji bi ukljuÄivao i aktivnu ulogu psihijatra u lijeÄenju iste, a u cilju redukcije kronifikacije smetnji kako bi se poboljÅ”ala kvaliteta života ovih pacijenata te pomoglo bolesnicima u razvijanju adekvatnih strategija suoÄavanja koje bi im omoguÄile bolje noÅ”enje sa boleÅ”Äu.Skin occupies a special place in psychiatry because it express different emotions such as anger, fear, shame, and others. The skin plays an important role in the socialization process that begins in childhood and continues to adulthood. The link between the skin and the brain is also reflected in their common ectodermal origin, and common hormonal and neurotransmitter systems.
The purpose of this study was to examine the differences between acute and chronic urticaria subjects in satisfaction with life, coping strategies, personality traits, anxiety, depression and perception of stress One hundred and fifty (150) subjects with urticaria were divided into 2 groups after 6 weeks of standardized dermatology treatment (88 acute and 62 chronic urticaria subjects). At baseline, all subjects answered the following questionnaires: Satisfaction with Life Scale-SWLS, Personal Wellbeing Index-PWI-A, The Multidimensional Coping Inventory ā COPE, Beck Depression inventory-BDI, State trait Anxiety Inventory -STAI, Perception of stress scale-PSS, Eysenck Personality Questionnaire - EPQ and General questionnaire - age, gender, education, employment, marital and parental status. After six weeks all the participants were re-tested with 2 questionnaires: Satisfaction with life scale and Personal wellbeing index. Subjects with acute urticaria are more satisfied with their lives than patients with chronic urticaria after 6 weeks. Participants with acute urticaria largely used emotion-focused coping, positive reinterpretation and growth, supression of competing activities than patients with chronic urticaria. Subjects with acute urticaria seek social support for emotional issues and for the instrumental reason to a greater degree than patients with chronic urticaria. Subjects with chronic urticaria use venting of emotions and mental disengagement to a lesser degree than subjects with acute urticaria.
The higher neuroticism in subjects with acute urticaria is, the greater is using problem-focused coping, emotion-focused coping and avoidance. A higher level of anxiety as a state in participants with acute urticaria leads to use of emotion-focused coping and avoidance. The higher neuroticism in subjects with chronic urticaria results in frequent use of avoidance. A higher level of anxiety as a state and personality trait in participants with chronic urticaria leads to more frequent use of avoidance. Higher levels of neuroticism and anxiety (as a personality trait and as a condition) in patients with acute and chronic urticaria, results in higher depression, greater perception of stress and frequent use of avoidance.
Based on the obtained results, there is a need for interdisciplinary approach in the treatment of urticaria, which would include the active role of the psychiatrist in the treatment, with the aim of reduction of chronification of the disorder in order to improve the quality of life of those patients, and also to help patients to develop appropriate coping strategies that would enable them to better cope with the disease
Intensive psychiatric care ā psychiatric emergencies
Intenzivna psihijatrijska skrb jest vrsta psihijatrijskog lijeÄenja bolesnika koja se provodi
na zatvorenom psihijatrijskom odjelu i po moguÄnosti u jedinici intenzivnog lijeÄenja, a
sadržaji su joj dijagnostika, lijeÄenje i opservacija hitnih stanja, odnosno bolesnika u psihijatriji.
UkljuÄuje sveobuhvatnu razinu skrbi, 24-satnu opservaciju te moguÄnost fiziÄkog sputavanja
i odvajanja bolesnika u sluÄaju gubitka kapaciteta za samokontrolu. NajÄeÅ”Äa hitna stanja
koja zahtijevaju intenzivnu psihijatrijsku skrb jesu suicidalnost, auto i hetero agresivnost
i krizna stanja. Pregled bolesnika ukljuÄuje anamnezu, heteroanamnezu, opis psihijatrijskog
statusa, opÄi somatski i neuroloÅ”ki pregled, laboratorijske pretrage, a ponekad CT i MRI mozga.
U lijeÄenju hitnog psihijatrijskog bolesnika upotrebljavaju se psihofarmakoterapija, psihoterapija
(kratka, individualna dinamski orijentirana, ventilacija, debriefing, suportivna psihoterapija
i obiteljska), te ponekad fiziÄko sputavanje i odvajanje bolesnika u izolacijsku
prostoriju zbog moguÄe opasnosti za sebe i/ili okolinu. Älanovi medicinskog tima su psihijatri
te medicinske sestre i tehniÄari koji su struÄno i posebno educirani u kliniÄkoj hitnoj psihijatriji
i koji Äe odmah po prijamu bolesnika odrediti prioritete postupaka, dijagnostike i lijeÄenja.
Vrijeme provedeno u jedinici za intenzivnu psihijatrijsku skrb razliÄito je, ali najÄeÅ”Äe je
od 2 do 6 dana. Po smirivanju akutne kliniÄke slike koja je i bila razlogom prijama u takvu jedinicu,
bolesnika se premjeÅ”ta na odgovarajuÄi psihijatrijski odjel sukladno njegovom opÄem
psihofiziÄkom stanju i psihijatrijskoj dijagnozi. Iako se opÄenito misli da su postupci intenzivne
psihijatrijske skrbi ponekad naglaÅ”eno specifiÄni ili izvan okvira kompetencija osoblja koje
radi u tim jedinicama, one su nužne i medicinski opravdane.Intensive psychiatric care is a type of psychiatric treatment of patients conducted in
a closed psychiatric ward, and engages the diagnosis and treatment of psychiatric emergencies.
Includes a comprehensive level of care, 24-hour observation, and the possibility of physical
restraint and isolation of patients in the event of loss of capacity for self-control. Psychiatric
disorders treated in such departments are deteriorating mental state within the various mental
disorders. The most common emergencies that require intensive psychiatric care are suicide,
auto and hetero aggressiveness and states of crisis. Examination of the patient includes
medical history, heteroanamnesis, description of psychiatric status, general and neurological
examination, laboratory tests, and sometimes CT and MRI of the brain. In order to take care of
urgent psychiatric patients in use is pharmacotherapy, psychotherapy (brief, individual dynamically
oriented, ventilation, debriefing, supportive and family psychotherapy), and sometimes
physical restraint and isolation of patients in isolation room because of possible danger to
himself and / or the environment. The principal members of the medical team are psychiatrists,
nurses and technicians who are highly qualified and trained in clinical psychiatry emergency
and will immediately determine procedure, diagnosis and treatment of the patient.
Time spent in psychiatric intensive care unit varies, but is usually from 2-6 days. By calming the
acute clinical picture which is the reason for admission to such department, the patient is
transferred to other psychiatric wards in accordance with its general mental and physical condition
and psychiatric diagnosis. Although it is generally thought that the procedures for intensive
psychiatric care is sometimes too hard or beyond the competence of personnel working
in such departments, they are medically necessary and justified
Satisfaction with life and coping skills in the acute and chronic urticaria
The purpose of this study was to examine the differences in satisfaction with life and coping strategies between patients with acute and chronic urticaria. Sixty patients with urticaria were divided into 2 groups after 6 weeks of standardized dermatology treatment (33 patients with acute and 27 patients with chronic urticaria). At baseline, all patients answered the following questionnaires: Satisfaction with Life Scale (SWLS), Personal Wellbeing Index (PWI-A), The Multidimensional Coping Inventory (COPE) and General questionnaire (age, gender, education, employment, marital status). After six weeks all the participants were re-tested with 2 questionnaires: SWLS and PWI-A. Results: Six weeks after the initial testing there was a statistically significant difference in satisfaction with life between patients with acute and chronic urticaria. Patients with acute urticaria were more satisfied with their lives than patients with chronic urticaria. Also, there was a statistically significant difference in the use of emotion-focused coping, seeking social support for emotional reasons and seeking social support for instrumental reasons. Patients with acute urticaria used emotion-focused coping and sought social support for emotional and instrumental reasons to a greater degree than patients with chronic urticaria. Patients with acute urticaria were more satisfied with their lives than patients with chronic urticaria. Patients with acute urticaria used emotion-focused coping and sought social support for emotional and instrumental reasons to a greater degree than patients with chronic urticaria
Influence of Personality Traits on Sexual Functioning of Patients Suffering from Schizophrenia or Depression
Aim of this research was to establish effects and influence of personality traits on sexual functioning of schizophrenic
and depressive patients, compared to healthy individuals. 300 participants were included in this research. For patients
suffering from schizophrenia it was established that the more they are open to experience and the less they are neurotic
their sexual drive is stronger. For patients suffering from depression it was established that the more they are open to experience
and conscientious and the less they are agreeable their sexual drive is stronger. Furthermore, higher openness is
a significant predictor for easier sexual arousal and the more those patients are conscientious and the less they are agreeable
easier is for them to achieve orgasms. Personality traits proved to be significant predictors of sexual functioning in
schizophrenic and depressive patients, but not in healthy individuals