The cytologic investigation of brow adipose tissue of D.laniger Felten Storch, 1968 Mammalia: Rodentia in hibernation

T his study was conducted on the D.laniger samples maintained in the laboratory condition after collecting from the natural environment. Investigations were performed in the experimental groups in the active period at the time of hibernation and at the period of intermediate awakening during hibernation. The brown adipose tissue BAT of these animals investigated was removed by dissection. The tissue samples dissected were prepared for the analysis at Transmission Electron Microscopy TEM and photographed. It was observed for the D. laniger BAT cells in the active period that there are high amount mitochondria and whereas the scarce amount of the lipid droplets. However, it was drawn attention to BAT cell of animals in hibernation that there plenty of capillary vessels and lipid droplets between them. The contact between lipid droplets with each other in the cytoplasm of animal at intermediate awakening in the winter during hibernation and cytoplasmic material loss and melting of mitochondria cristae partly were observed. These results of this study suggest that it may be useful to understand the importance of the brown adipose tissue of some hibernating mammal

N-(2,6-Dimethyl-3-oxo-1-thia-4-aza­spiro­[4.5]dec-4-yl)-2-hydr­oxy-2,2-di­phenyl­acetamide

In the title compound, C24H28N2O3S, the pendant methyl C atom bonded to the cyclo­hexane ring is disordered over two sites in a 0.580 (11):0.420 (11) ratio. The cyclo­hexane ring adopts a distorted chair conformation while the thia­zolidine ring has an envelope conformation. The two phenyl rings make a dihedral angle of 71.8 (2)° with each other. The conformation is stabilized by an intra­molecular N—H⋯O hydrogen bond. In the crystal structure, an inter­molecular hydrogen bond O—H⋯O occurs