Breast Reconstruction Outcome:patient Satisfaction, Quality of Life and Complications

The aim of this study was to compare the outcome of breast reconstruction after mastectomy, in the context of a breast cancer diagnosis or risk, between reconstruction with implants (alloplastic) and with own body tissue of the lower abdomen (autologous) based on 1. patient satisfaction, 2. quality of life and 3. postoperative complications.The results of this study concluded that women were more satisfied and experienced a higher quality of life after undergoing reconstruction with their own tissue compared to reconstruction with breast implants (70 versus 63, scale: 0-100). In addition, women who underwent reconstruction with their own tissue scored comparable on breast satisfaction with women from the same age group of the general population (Groningen, the Netherlands) who had never had their breasts operated on (70 versus 68 points, scale: 0-100). Women with a higher BMI are generally less satisfied with their own breasts. The removal of belly fat, resulting in changes in physique and fat distribution, then reconstructing it into a new breast, may possibly contribute to the significant increase in patient satisfaction and quality of life among women undergoing autologous reconstruction.Furthermore, several risk factors for developing complications after breast reconstruction were identified in this study. For example, in women who smoke, have a high BMI and/or a moderate muscle quality, the chance of getting complications after breast reconstruction is significantly increased. In these women, it must be considered whether breast reconstruction should be postponed until women have stopped smoking, have lost weight and are in better physical condition

Environmental life cycle assessment of industrialization process of calcined dredged sediments

This research focus on the life cycle assessment (LCA) of dredged sediments valorization. This tool is part of an environmental management approach, which makes it possible to compare the environmental loads of the different stages of the life cycle of the same product and, by the way to deduce the most polluting step in environmental terms and thus the industrialization process of dredging sediments of dams is optimized by modelling using the GEMIS (Global Emission Model for Integrated Systems) 4.95 software and the classification and characterization method. To propose a model that is the more respectful of the environment, by determining the most environmentally friendly scenario, in order to exploit these dredged sediments after calcination treatment to make them active in the field of the building’s construction. The results of this life cycle analysis study of the new industrialization process of dredged sediments show that climate change potential (GHG) is 0,246 ton of CO2eq/t of sediments, acidification potential is 4,55×10-4 ton of SO2 eq/t of sediments, the tropospheric ozone precursor potential is 9,97×10-4 ton of TOPP eq/t of sediments and the cumulative energy and exergy demand is 2506,75 in MJ/t of sediments, these values are compared to others carried out in Algeria

Environmental life cycle assessment of industrialization process of calcined dredged sediments

This research focus on the life cycle assessment (LCA) of dredged sediments valorization. This tool is part of an environmental management approach, which makes it possible to compare the environmental loads of the different stages of the life cycle of the same product and, by the way to deduce the most polluting step in environmental terms and thus the industrialization process of dredging sediments of dams is optimized by modelling using the GEMIS (Global Emission Model for Integrated Systems) 4.95 software and the classification and characterization method. To propose a model that is the more respectful of the environment, by determining the most environmentally friendly scenario, in order to exploit these dredged sediments after calcination treatment to make them active in the field of the building’s construction. The results of this life cycle analysis study of the new industrialization process of dredged sediments show that climate change potential (GHG) is 0,246 ton of CO2eq/t of sediments, acidification potential is 4,55×10-4 ton of SO2 eq/t of sediments, the tropospheric ozone precursor potential is 9,97×10-4 ton of TOPP eq/t of sediments and the cumulative energy and exergy demand is 2506,75 in MJ/t of sediments, these values are compared to others carried out in Algeria

Environmental life cycle assessment of industrialization process of calcined dredged sediments

This research focus on the life cycle assessment (LCA) of dredged sediments valorization. This tool is part of an environmental management approach, which makes it possible to compare the environmental loads of the different stages of the life cycle of the same product and, by the way to deduce the most polluting step in environmental terms and thus the industrialization process of dredging sediments of dams is optimized by modelling using the GEMIS (Global Emission Model for Integrated Systems) 4.95 software and the classification and characterization method. To propose a model that is the more respectful of the environment, by determining the most environmentally friendly scenario, in order to exploit these dredged sediments after calcination treatment to make them active in the field of the building’s construction. The results of this life cycle analysis study of the new industrialization process of dredged sediments show that climate change potential (GHG) is 0,246 ton of CO2eq/t of sediments, acidification potential is 4,55×10-4 ton of SO2 eq/t of sediments, the tropospheric ozone precursor potential is 9,97×10-4 ton of TOPP eq/t of sediments and the cumulative energy and exergy demand is 2506,75 in MJ/t of sediments, these values are compared to others carried out in Algeria

Outcome of Quality of Life for Women Undergoing Autologous versus Alloplastic Breast Reconstruction following Mastectomy:A Systematic Review and Meta-Analysis

Background: This review aimed to meta-analyze the quality of life of alloplastic versus autologous breast reconstruction, when measured with the BREAST-Q. Methods: An electronic PubMed and EMBASE search was designed to find articles that compared alloplastic versus autologous breast reconstruction using the BREAST-Q. Studies that failed to present BREAST-Q scores and studies that did not compare alloplastic versus autologous breast reconstruction were excluded. Two authors independently extracted data from the included studies. A standardized data collection form was used. Quality was assessed using the Newcastle-Ottawa Scale. The mean difference and 95 percent confidence intervals between breast reconstruction means were estimated for each BREAST-Q subscale. Forest plots and the I2statistic were used to assess heterogeneity and funnel plot publication bias. The Z test was used to assess overall effects. Results: Two hundred eighty abstracts were found; 10 articles were included. Autologous breast reconstruction scored significantly higher in the five subscales than alloplastic breast reconstruction. The Satisfaction with Breasts subscale indicated the greatest difference, with a mean difference of 6.41 (95 percent CI, 3.58 to 9.24; I2= 70 percent). The Satisfaction with Results subscale displayed a mean difference of 5.52. The Sexual Well-Being subscale displayed a mean difference of 3.85. The Psychosocial Well-Being subscale displayed a mean difference of 2.64. The overall difference in physical well-being was significant, with high heterogeneity (mean difference, 3.33; 95 percent CI, 0.18 to 6.48; I2= 85). Conclusion: Autologous breast reconstruction had superior outcomes compared with alloplastic breast reconstruction as measured by the BREAST-Q

A Dutch Cross-sectional Population Survey to Explore Satisfaction of Women with their Breasts

BACKGROUND: Little is known about how satisfied women are with their breasts and which factors influence breast satisfaction. Therefore, the aim of this study was to elucidate this by collecting data on breast satisfaction from the general population in relation to age, body mass index, lifestyle, psychological, and physical well-being. METHOD: This study was a cross-sectional population survey performed in 2019 in the north of the Netherlands, among randomly selected women between 20 and 80 years. Breast satisfaction was measured in the 1334 participants with the preoperative reconstruction BREAST-Q module. Other applied questionnaires were the Hospital Anxiety and Depression Scale, Short Form Survey (SF-36), and a custom-made questionnaire on lifestyle and baseline characteristics. Representativeness was assessed by comparing the participants with Dutch normative data. Possible factors influencing “satisfaction with breasts” were analyzed using multivariate linear regression analyses. RESULTS: The median (IQR) BREAST-Q score for “satisfaction with breasts” was mediocre: 63 (58–79) on a 0–100 scale. Higher age and higher SF-36 scores had a positive effect on breast satisfaction (P < 0.001 and P < 0.001, respectively) and a higher body mass index, smoking and anxiety score greater than 8 were negatively associated (P < 0.001, P = 0.013 and P < 0.001 respectively, multivariate linear regression analyses). CONCLUSION: These data are the first European normative data and can serve as a reference in future population and patient-based studies regarding breast satisfaction

Authenticating the origin of different shrimp products on the Tunisian markets by PCR/RFLP method

This study describes a polymerase chain reaction using restriction fragment length polymorphism (PCR-RFLP) assay based on the 16S rRNA mitochondrial gene to identify commercial food products of wide range of Penaeidae and Pandalidae shrimp species commercialised in the Tunisian market. Phylogenetic analyses on 16S rRNA mitochondrial gene were used to study the relationships among the considered species. Penaeidae shrimp species was easily differentiated and confirmed by direct sequencing, showing a genetic distance of 0.34 with respect to Pandalidae species. A rapid and reliable PCR method using restriction fragment length polymorphism (RFLP) with three restriction enzymes (HpyCH4III/ MboI / AluI) was optimized for unambiguous differentiation of shrimp from 19 commercial market samples (raw and processed products). Results showed that the restriction fragment length polymorphism technique can be used to identify Tunisian shrimp species and thus to control not only commercial fraud but also efficient restocking program

Chitosan Treatment of E-11 Cells Modulates Transcription of Nonspecific Immune Genes and Reduces Nodavirus Capsid Protein Gene Expression

This study explores whether crustacean products inhibit viral infections in aquaculture. Chitosan (CHT) was extracted from waste products of Parapenaeus longirostris. Biochemical composition, viscosity measurement, molecular weight, structure and cytotoxicity tests were used to characterize the extracted chitosan. Cultures of E-11 cells derived from snakehead Ophicephalus striatus were inoculated with 106.74 TCID50 of an isolate of betanodavirus genotype RGNNV (redspotted grouper nervous necrosis virus) after being treated with solutions of 0.3% CHT for 1 h at room temperature. The antiviral effect of CHT was assessed by comparing the ability of RGNVV to replicate and produce cytopathic effects on CHT-treated cell cultures. The change in RNA expression levels of the nodavirus capsid protein gene and three mediator genes in infected cells with or without CHT treatment was evaluated by qPCR. Changes in gene expression compared to control groups were monitored at 6, 24, 48 and 71 h post treatment in all target gene transcripts. The CCR3 expression in CHT treated cells showed a significant increase (p &lt; 0.05) until day 3. On the other hand, the expression of TNF-α decreased significantly (p &lt; 0.05) in CHT treated cells throughout the experimental period. Likewise, the expression of the IL-10 gene showed a significant downregulation in CHT treated cells at all time points (p ≤ 0.05). As further evidence of an antiviral effect, CHT treatment of cells produced a reduction in virus load as measured by a reduced expression of the viral capsid gene and the increase in RQ values from 406 ± 1.9 at hour 1 to 695 ± 3.27 at 72 h post inoculation. Statistical analysis showed that the expression of the viral capsid gene was significantly lower in cells treated with chitosan (p ≤ 0.05). These results improve our knowledge about the antiviral activity of this bioactive molecule and highlight its potential use in fish feed industry

Influence of calcined mud on the mechanical properties and shrinkage of self-compacting concrete

The use of SCC has a particular interest in terms of sustainable development. Indeed, their specific formulation leads to a greater volume of dough than for common concretes, thus, a larger quantity of cement. However, for economical, ecological and technical reasons, it is sought to limit their cement content [1]. It is therefore necessary to almost always use mineral additions as a partial replacement for cement because the technology of self-compacting concretes can consume large quantities of fines, in this case calcinated mud issued from dams dredging sediments that can give and/or ameliorate characteristics and performances of this type of concretes. Four SCCs had been formulated from the same composition where the only percentage of calcinated mud of Chorfa (west of Algeria) dam changed (0%, 10%, 20% and 30%). The effect of calcinated mud on characteristics at fresh state of SCC according to AFGC was quantified. Mechanical strengths and shrinkage deformation (total, autogenous, drying) were evaluated. The results show the possibility to make SCCs with different dosages of calcinated mud having strengths that can defy those of the control SCC. The analysis of free deformations indicates the beneficial impact of the mud by contributing to decrease the amplitudes of the shrinkage compared to those of the control SCC