Kulttuurimakasiini L3:käyttötarkoituksenmuutoksen konseptisuunnitelma Lars Sonckin satamamakasiiniin

Tiivistelmä. Diplomityön kohde on Lars Sonckin suunnittelema, vuonna 1924 valmistunut varastomakasiini L3, joka sijaitsee Helsingin Jätkäsaaressa. Diplomityön päätavoitteena on laatia taustoituksen avulla tyhjillään olevaan makasiinirakennukseen konseptisuunnitelma käyttötarkoituksenmuutoksesta, jossa rakennus muutetaan kaupunkilaisille avoimeksi Kulttuurimakasiiniksi. Helsingin kaupunki on järjestänyt rakennuksesta konseptitason suunnittelukilpailun, jota ei ratkaistu diplomityön laatimisen aikana. Työn aluksi luvussa kaksi perehdyn tarkemmin Jätkäsaaren aluehistoriaan sekä L3- makasiinin rakentamiseen, arkkitehti Lars Sonckin alkuperäiseen suunnitelmaan sekä rakennuksen eri vaiheisiin sen satavuotisen elinkaaren ajalta. Luku kolme käsittelee rakennuksen nykytilaa. Pohdin sen arvoja ja identiteettiä eri näkökulmin ja kriteerein ja perehdyn mahdollisuuksiin ja vaatimuksiin, joita ympäristö rakennukselle asettaa. Käsittelen voimassaolevaa asemakaavaa ja suojelukysymystä. Analysoin rakennuksen tunnelmaa, muutoshistoriaa ja rakennustaiteellisia arvoja. Luvussa esitellään myös kohteesta järjestetyn konseptikilpailun tilannetta. Luvussa neljä vertailen makasiinia Helsingin kantakaupungin säilyneeseen satamarakennuskantaan sekä Lars Sonckin muuhun tuotantoon. Viidennessä luvussa tutkin tarkemmin paikkaa ja paikan henkeä, sekä makasiinin roolia kantakaupungin laajuisessa kontekstissa. Kuudennessa luvussa esitän makasiinirakennukselle uuden käyttötarkoituksen vetovoimaisena Kulttuurimakasiinina. Suunnitelma käsittää konseptitasoiset pohjapiirustukset, aluesuunnitelman, leikkauksen, julkisivupiirustukset, havainnekuvat sekä toimintaa havainnollistavia kaavioita. Rakennuksen nykytila jää osin valistuneiden arvioiden varaan, sillä vieraileminen tiloissa ei onnistunut prosessin aikaan vallitsevan koronavirustilanteen vuoksi. Nykytilaa on arvioitu ajantasaisten rakennuspiirustusten ja valokuvien avulla. Työ ei sisällä makasiinin tilojen ja rakenteiden nykytilan ja kunnon inventointia, eikä rakennukselle ehdoteta yksityiskohtaista restaurointisuunnitelmaa. Suunnitelman lähtökohtana ovat olleet alkuperäiset, säilyneet rakennusosat.Culture Warehouse L3 : concept design of adaptive reuse for Lars Sonck’s harbour warehouse. Abstract. The subject of this diploma thesis is the L3 warehouse, a storage building situated in Jätkäsaari, Helsinki. The building was designed by architect Lars Sonck and built in 1924. The main purpose of the thesis is to compose an adaptive reuse concept design for the empty warehouse building and transform it into a Culture Warehouse, an open meeting place for the citizens of Jätkäsaari and the whole of Helsinki. The city of Helsinki has launched a concept-level design competition of the warehouse, which was not resolved during the thesis process. In the beginning of the thesis in chapter two I get acquainted with the regional history of Jätkäsaari and the building process of the L3 warehouse, architect Lars Sonck’s original plans and the building’s different phases over its 100-year history. Chapter three focuses on the building’s present state. I ponder its identity and values from different perspectives, and orientate myself with the possibilities and demands placed on the building by its surrounding environment. I address the building’s status in the city plan and the conservation issues that are imposed upon the building, and later analyze the its ambience, alteration history and architectural values. The chapter also sheds light on the design competition around the L3 warehouse. In chapter four I compare the warehouse to other remaining harbour buildings in the center of Helsinki, as well as to other works of architect Lars Sonck. The fifth chapter includes a brief analysis of the warehouse’s role in the cityscape of central Helsinki, followed by a subchapter on the genius loci of the building. In the sixth chapter I present the concept design of an alluring Culture Warehouse. The design consists of concept-level floor plans, an area plan, a section drawing, facade drawings, rendered illustrations and explanatory diagrams. The present state of the L3 remains partly unclear due to coronavirus restrictions on visits in the building. The present situation is evaluated through up-to-date floor plans, sections and facade drawings, as well as photographs. The thesis does not contain any inventory of the condition nor the spaces of the L3; thereby it doesn’t include a proposal for a detailed restoration plan. The original preserved building parts have been the starting point for the design concept of this thesis

Kerrostalo Vuosaareen

Tiivistelmä. Yhdyskuntasuunnittelun kurssilla suunnittelemamme asemakaavan pohjalta suunnittelin kerrostalon Helsingin Vuosaareen. Yhdyskuntasuunnittelun suunnitelmamme tärkeimpiä tavoitteita olivat tehokas ja tiivis kaupunkirakentaminen, sekoitetut asumisen muodot, omaleimaiset korttelit, asumisen laadun takaaminen sekä vehreyden säilyttäminen merellisen Vuosaaren alueella. Valitsin asuntosuunnittelun kurssille suurkorttelista keskeisen lamellin, joka asettuu sisäpihaan nähden miellyttävään kohtaan, ja tarjoaa upeita näkymiä eläväisen keskusaukion suuntaan. Alkuvaiheessa suunnittelutyö takkusi, kunnes inspiroiduin terassitaloratkaisusta. Vaihtelevat pohjat ja epätavanomainen rakenne houkuttelivat kehittämään ajatusta pidemmälle. Runkosyvyys tuotti päänvaivaa heti alussa, mikä teki suunnittelutyöstä ja prosessista kasvattavan ja hyvin mielenkiintoisen. Kerrostalo on viisikerroksinen, tummanharmaalla tiilellä verhoilut terassitalo, joka terassoituu lännen suuntaan. Sisäpihan puolella julkisivu on ”suora”, ja sitä elävöittävät symmetrisesti sijoitetut, puoliksi sisäänvedetyt kuutioparvekkeet. Tiilen lisäksi julkisivuissa on käsittelemätöntä kuusiverhoilua, joka harmaantunee ajan mittaan. Ensimmäisessä kerroksessa sijaitsevat asuinkerrostalon yhteistilat, vuokrattava ateljeetyötila sekä liiketilat, jotka avautuvat julkisen tilan puolelle rakennuksen länsipuolelle. Yhteistiloista lastenvaunuvarasto, ulkovälinevarasto ja pesutupa sijaitsevat ensimmäisessä kerroksessa, häkkivarastot puolestaan rakennuksen kellarikerroksesta, josta on pääsy pihan alapuolella olevaan parkkihalliin. Toinen kerros käsittää yksiöiden sarjan, jotka avautuvat pääasiassa lännen suuntaan saaden oman aurinkoisen terassin. Pihan puoliset asunnot ovat kaksioita, joissa on molemmissa kaksi parveketta. Kolmas kerros kapenee edelleen lännen puolelta, ja runkosyvyys tekeekin asuntosuunnittelusta luontevampaa muodostaen kaksiota sekä hulppeampia läpitalon kolmioita. Neljännessä kerroksessa on ainoastaan kaksi suurta asuntoa, sopien suurperheelle, tai esimerkiksi kaveriporukalle kimppakämpän muodossa. Viidennessä kerroksessa sijaitsee asukkaiden yhteinen talosauna sekä kaksi keskikokoista asuntoa. Perusperiaatteina kerrostalon suunnittelutyössä halusin säilyttää monipuolisen asuntotarjonnan kirjon, asumismukavuuden nostamisen uudelle tasolle terassien avulla, sekä persoonallisen näköisen rakennuksen ilmeen luomisen

Breakdown of long-range temporal correlations in theta oscillations in patients with major depressive disorder

Neuroimaging has revealed robust large-scale patterns of high neuronal activity in the human brain in the classical eyes-closed wakeful rest condition, pointing to the presence of a baseline of sustained endogenous processing in the absence of stimulus-driven neuronal activity. This baseline state has been shown to differ in major depressive disorder. More recently, several studies have documented that despite having a complex temporal structure, baseline oscillatory activity is characterized by persistent autocorrelations for tens of seconds that are highly replicable within and across subjects. The functional significance of these long-range temporal correlations has remained unknown. We recorded neuromagnetic activity in patients with a major depressive disorder and in healthy control subjects during eyes-closed wakeful rest and quantified the long-range temporal correlations in the amplitude fluctuations of different frequency bands. We found that temporal correlations in the theta-frequency band (3-7 Hz) were almost absent in the 5-100 s time range in the patients but prominent in the control subjects. The magnitude of temporal correlations over the left temporocentral region predicted the severity of depression in the patients. These data indicate that long-range temporal correlations in theta oscillations are a salient characteristic of the healthy human brain and may have diagnostic potential in psychiatric disorders. We propose a link between the abnormal temporal structure of theta oscillations in the depressive patients and the systems-level impairments of limbic-cortical networks that have been identified in recent anatomical and functional studies of patients with major depressive disorder. Copyright © 2005 Society for Neuroscience

Effect of information about organic production on beef liking and consumer willingness to pay

The present study was aimed to assess the effect of information about organic production on beef liking and consumer willingness to pay. Mean scores of perceived liking were higher for organic beef (OB) as compared to conventional beef (CB). Expected liking scores were higher for OB than for CB. For OB the expected liking was significantly higher than the perceived liking expressed in blind conditions (negative disconfirmation), whereas for CB no difference was observed. Consumers completely assimilated their liking for OB in the direction of expectations. Consumers showed a willingness to pay for OB higher than the suggested price (P < 0.001), the latter corresponding to the local commercial value for organic beef. We conclude that the information about organic farming can be a major determinant of beef liking, thus providing a potential tool for meat differentiation to traditional farms

Symbolic Partial-Order Execution for Testing Multi-Threaded Programs

We describe a technique for systematic testing of multi-threaded programs. We combine Quasi-Optimal Partial-Order Reduction, a state-of-the-art technique that tackles path explosion due to interleaving non-determinism, with symbolic execution to handle data non-determinism. Our technique iteratively and exhaustively finds all executions of the program. It represents program executions using partial orders and finds the next execution using an underlying unfolding semantics. We avoid the exploration of redundant program traces using cutoff events. We implemented our technique as an extension of KLEE and evaluated it on a set of large multi-threaded C programs. Our experiments found several previously undiscovered bugs and undefined behaviors in memcached and GNU sort, showing that the new method is capable of finding bugs in industrial-size benchmarks.Comment: Extended version of a paper presented at CAV'2

Health promoting potential of herbal teas and tinctures from Artemisia campestris subsp maritima: from traditional remedies to prospective products

This work explored the biotechnological potential of the medicinal halophyte Artemisia campestris subsp. maritima (dune wormwood) as a source of health promoting commodities. For that purpose, infusions, decoctions and tinctures were prepared from roots and aerial-organs and evaluated for in vitro antioxidant, anti-diabetic and tyrosinase-inhibitory potential, and also for polyphenolic and mineral contents and toxicity. The dune wormwood extracts had high polyphenolic content and several phenolics were identified by ultra-high performance liquid chromatography-photodiode array-mass-spectrometry (UHPLC-PDA-MS). The main compounds were quinic, chlorogenic and caffeic acids, coumarin sulfates and dicaffeoylquinic acids; several of the identified phytoconstituents are here firstly reported in this A. campestris subspecies. Results obtained with this plant's extracts point to nutritional applications as mineral supplementary source, safe for human consumption, as suggested by the moderate to low toxicity of the extracts towards mammalian cell lines. The dune wormwood extracts had in general high antioxidant activity and also the capacity to inhibit a-glucosidase and tyrosinase. In summary, dune wormwood extracts are a significant source of polyphenolic and mineral constituents, antioxidants and a-glucosidase and tyrosinase inhibitors, and thus, relevant for different commercial segments like the pharmaceutical, cosmetic and/or food industries.FCT - Foundation for Science and Technology [CCMAR/Multi/04326/2013]; Portuguese National Budget; FCT [IF/00049/2012, SFRH/BD/94407/2013]; Research Foundation - Flanders (FWO) [12M8315N]info:eu-repo/semantics/publishedVersio

The neurochemical basis of human cortical auditory processing: combining proton magnetic resonance spectroscopy and magnetoencephalography

BACKGROUND: A combination of magnetoencephalography and proton magnetic resonance spectroscopy was used to correlate the electrophysiology of rapid auditory processing and the neurochemistry of the auditory cortex in 15 healthy adults. To assess rapid auditory processing in the left auditory cortex, the amplitude and decrement of the N1m peak, the major component of the late auditory evoked response, were measured during rapidly successive presentation of acoustic stimuli. We tested the hypothesis that: (i) the amplitude of the N1m response and (ii) its decrement during rapid stimulation are associated with the cortical neurochemistry as determined by proton magnetic resonance spectroscopy. RESULTS: Our results demonstrated a significant association between the concentrations of N-acetylaspartate, a marker of neuronal integrity, and the amplitudes of individual N1m responses. In addition, the concentrations of choline-containing compounds, representing the functional integrity of membranes, were significantly associated with N1m amplitudes. No significant association was found between the concentrations of the glutamate/glutamine pool and the amplitudes of the first N1m. No significant associations were seen between the decrement of the N1m (the relative amplitude of the second N1m peak) and the concentrations of N-acetylaspartate, choline-containing compounds, or the glutamate/glutamine pool. However, there was a trend for higher glutamate/glutamine concentrations in individuals with higher relative N1m amplitude. CONCLUSION: These results suggest that neuronal and membrane functions are important for rapid auditory processing. This investigation provides a first link between the electrophysiology, as recorded by magnetoencephalography, and the neurochemistry, as assessed by proton magnetic resonance spectroscopy, of the auditory cortex

Free Radical Scavenging and Analgesic Activities of Cucumis sativus L. Fruit Extract

The aqueous fruit extract of Cucumis sativus L. was screened for free radical scavenging and analgesic activities. The extract was subjected to in vitro antioxidant studies at 250 and 500 μg/ml and analgesic study at the doses 250 and 500 mg/kg, respectively. The free radical scavenging was compared with ascorbic acid, BHA (Butylated hydroxyl anisole), whereas, the analgesic effect was compared with Diclofenac sodium (50 mg/kg). The C. sativus fruit extract showed maximum antioxidant and analgesic effect at 500 μg/ml and 500 mg/kg, respectively. The presence of flavonoids and tannins in the extract as evidenced by preliminary phytochemical screening suggests that these compounds might be responsible for free radical scavenging and analgesic effects