3,350 research outputs found

    Oxidative phosphorylation efficiency, proton conductance and reactive oxygen species production of liver mitochondria correlates with body mass in frogs

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    ody size is a central biological parameter affecting most biological processes (especially energetics) and mitochondria is a key organelle controlling metabolism and is also the cell's main source of chemical energy. However, the link between body size and mitochondrial function is still unclear, especially in ectotherms. In this study, we investigated several parameters of mitochondrial bioenergetics in the liver of three closely related species of frogs (the common frog Rana temporaria, the marsh frog Pelophylax ridibundus and the bull frog Lithobates catesbeiana). These particular species were chosen due to their differences in adult body mass. We found that the mitochondrial coupling efficiency was markedly increased with animal size, which lead to a higher ATP production (+70%) in the larger frogs (L. catesbeiana) compared to the smaller frogs (R. temporaria). This was essentially driven by a strong negative dependence of mitochondrial proton conductance on body mass. Liver mitochondria from the larger frogs (L. catesbeiana) displayed 50% of the proton conductance of mitochondria from the smaller frogs (R. temporaria). Contrary to our prediction, the low mitochondrial proton conductance measured in L. catesbeiana was not associated with higher radical oxygen species production. Instead, liver mitochondria from the larger individuals produced significantly lower radical oxygen species than those from the smaller frogs. Collectively, the data shows that key bioenergetics parameters of mitochondria (proton leak, ATP production efficiency and radical oxygen species production) are correlated with body mass in frogs. This research expands our understanding of the relationship between mitochondrial function and the evolution of allometric scaling in ectotherms

    Thulium and ytterbium-doped titanium oxide thin films deposited by ultrasonic spray pyrolysis

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    Thin films of thulium and ytterbium-doped titanium oxide were grown by metal-organic spray pyrolysis deposition from titanium(IV)oxide bis(acetylacetonate), thulium(III) tris(2,2,6,6-tetramethyl-3,5-heptanedionate) and ytterbium(III) tris(acetylacetonate). Deposition temperatures have been investigated from 300{\deg}C to 600{\deg}C. Films have been studied regarding their crystallity and doping quality. Structural and composition characterisations of TiO2:Tm,Yb were performed by electron microprobe, X-ray diffraction and Fourier transform infrared spectroscopy. The deposition rate can reach 0.8 \mum/h. The anatase phase of TiO2 was obtained after synthesis at 400{\deg}C or higher. Organic contamination at low deposition temperature is eliminated by annealing treatments.Comment: 6 pages, 6 figure

    Relations entre les caractĂšres du milieu et les espĂšces ligneuses au Nord-Togo

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    Une analyse factorielle des correspondances a été effectuée sur 65 relevés de la strate ligneuse des savanes soudaniennes du Nord Togo. Cinq groupes d'espÚces et de relevés ont été individualisés. L'étude des facteurs écologiques qui conditionnent leur réalisation montre le rÎle essentiel de l'homme et des facteurs édaphique

    A Cryogenic Test Station for Subcooling Helium Heat Exchangers for LHC

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    The superconducting magnets of the Large Hadron Collider (LHC) will be cooled at 1.9 K by distributed cooling loops where counter-flow heat exchangers will be integrated. To qualify potential suppliers for the 250-units series production, prototypes of various technologies have been selected by CERN and a test station was set up at CEA-Grenoble. This test station, is constituted of a cryostat allowing an easy access to the heat exchanger to be tested as well as very low pressure pumping facilities

    SPIRE imaging of M 82: Cool dust in the wind and tidal streams

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    M 82 is a unique representative of a whole class of galaxies, starbursts with superwinds, in the Very Nearby Galaxy Survey with Herschel. In addition, its interaction with the M 81 group has stripped a significant portion of its interstellar medium from its disk. SPIRE maps now afford better characterization of the far-infrared emission from cool dust outside the disk, and sketch a far more complete picture of its mass distribution and energetics than previously possible. They show emission coincident in projection with the starburst wind and in a large halo, much more extended than the PAH band emission seen with Spitzer. Some complex substructures coincide with the brightest PAH filaments, and others with tidal streams seen in atomic hydrogen. We subtract the far-infrared emission of the starburst and underlying disk from the maps, and derive spatially-resolved far-infrared colors for the wind and halo. We interpret the results in terms of dust mass, dust temperature, and global physical conditions. In particular, we examine variations in the dust physical properties as a function of distance from the center and the wind polar axis, and conclude that more than two thirds of the extraplanar dust has been removed by tidal interaction, and not entrained by the starburst wind

    Real time decoherence of Landau and Levitov quasi-particles in quantum Hall edge channels

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    Quantum Hall edge channels at integer filling factor provide a unique test-bench to understand decoherence and relaxation of single electronic excitations in a ballistic quantum conductor. In this Letter, we obtain a full visualization of the decoherence scenario of energy (Landau) and time (Levitov) resolved single electron excitations at filling factor Μ=2\nu=2. We show that the Landau excitation exhibits a fast relaxation followed by spin-charge separation whereas the Levitov excitation only experiences spin-charge separation. We finally suggest to use Hong-Ou-Mandel type experiments to probe specific signatures of these different scenarios.Comment: 14 pages, 8 figure

    Logarithmic behavior of degradation dynamics in metal--oxide semiconductor devices

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    In this paper the authors describe a theoretical simple statistical modelling of relaxation process in metal-oxide semiconductor devices that governs its degradation. Basically, starting from an initial state where a given number of traps are occupied, the dynamics of the relaxation process is measured calculating the density of occupied traps and its fluctuations (second moment) as function of time. Our theoretical results show a universal logarithmic law for the density of occupied traps ˉ∌ϕ(T,EF)(A+Bln⁥t)\bar{} \sim \phi (T,E_{F}) (A+B \ln t), i.e., the degradation is logarithmic and its amplitude depends on the temperature and Fermi Level of device. Our approach reduces the work to the averages determined by simple binomial sums that are corroborated by our Monte Carlo simulations and by experimental results from literature, which bear in mind enlightening elucidations about the physics of degradation of semiconductor devices of our modern life
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