La responsabilidad civil de fabricante por productos defectuosos : estudio comparado de su proyección bajo una doctrina causal de imputabilidad según practicado en el derecho estadounidense

Tesis doctoral inédita, presentada en la Univ. Complutense de Madrid, Facultad de Derecho, Departamento de Derecho civil 1992.Depto. de Derecho CivilFac. de DerechoTRUEProQuestpu

La responsabilidad civil de fabricante por productos defectuosos : estudio comparado de su proyección bajo una doctrina causal de imputabilidad según practicado en el derecho estadounidense

Tesis doctoral inédita, presentada en la Univ. Complutense de Madrid, Facultad de Derecho, Departamento de Derecho civil 1992.Depto. de Derecho CivilFac. de DerechoTRUEProQuestpu

El Cardal (Ferreira), una explotación minera de los siglos III y II a. C. en las laderas septentrionales de Sierra Nevada (Granada)

El yacimiento arqueológico de El Cardal (F erre ira, Granada) constituye un recinto fortificado de los siglos III y 11 a. de C. Se relaciona con la explotación minera de El Marquesado del Cenete, donde también se constatan otros asentamientos similares como " El Peñón de Arruta".The archaeological site of El Cardal (Ferreira, Granada) is a fortification from the III and 11 century B.C. It is related to the mine explotation of Cenete's Marquesado, where there is another similar place like The Peñ.on de Arruta

El peñón de Arruta (Jeres del Marquesado, Granada): Una explotación minera romana

El yacimiento arqueológico de El Peflón de Arruta (Jeres del Marquesado, Granada) permite documentar un modelo de explotación minera romana, destinado al tratamiento del mineral, fortificado y datable entre fines del s. II a. C. e inicios del Principado, del que existen indicios de su existencia en otras zonas del sur de Hispania.The archaeological site of El Peflón de Arruta (Jéres del Marquesado, Granada) allows to provide evidence for a model of Roman mine explotation, destined to the treatment of the mineral, fortified and datable between end of ll century B.C. and begining of the Principate, traces of the existence of which model can also be found in other southem areas of Hispania

Kinematics of Structures and Basin Evolution in the Central High Atlas: constraints from AMS and Paleomagnetic Data

[EN] From the application of the magnetic techniques (Anisotropy of Magnetic Susceptibility and paleomagnetism) it can be seen that to determine the age (and origin) of structures in the Moroccan Central High Atlas is not straightforward from geometrical features only and that similar structures can have different origins, or that the two limbs of a particular structure can have developed at different times. A classification of structures is proposed showing all these possibilities. As a general rule, many structures were initiated before compression and, with local exceptions associated with salt structures, paleo-dips were shallow at the remagnetization stage. This has allowed the restoration of structures and the characterization of the overall geometry of the atlasic basin as a narrow, steer’s head strongly subsiding basin whose geometry strongly conditioned its tectonic inversion during the Cenozoic compressional stage. As a synthesis, the Central High Atlas constitutes a good example of intra-plate chain in which different models of basin formation (continental rifting, salt tectonics, transtension) and inversion (thrust tectonics, transpression, buttressing and internal deformation…) can be tested and visualized.This work is part of the I+D+i research projects CGL2009-10840, CGL2009-8969, CGL2012-38481, CGL2016-77560-C2 (C21 and C22) and PID2019-108753GB-C2 (C21 and C22), funded by mICIN/AEI/https://doi.org/10.13039/501100011033 and by “ERDF A way of making Europe”.Peer reviewe

Structure of the Central High Atlas (Morocco): constraints from Potential Field Data and 3D Models

[EN] From a 3-D reconstruction based on serial cross-sections, structural observations, and potential field geophysical data we characterize the major structural frame of the Moroccan Central High Atlas. Its overall structure shows two fold-and-thrust systems (each one showing particular features) at the northern and southern borders of the chain, resulting from the inversion of the Mesozoic basin. Five more zones can be distinguished in the inner part of the chain, according to their structural features, ranging from basement-involved structures in the westernmost sector to completely detached structures in the eastern part. Most compressional structures show an ENE-WSW (atlasic) trend, also pinpointed by the orientation of pressure-solution and slaty cleavage associated with the compressional stage. Large-scale faults of crustal or lithospheric reach can be inferred from the aeromagnetic maps, that show that the gabbro intrusions (some of them showing sigmoidal shape) are aligned in an E-W direction, oblique to the main trend. The overall compressional structure is controlled by a main, low-angle, South-verging thrust involving both the Mesozoic cover and the Paleozoic basement thrusting over the southern foreland of the chain. Branching on this surface there is a series of back-thrusts and faults, some of them resulting from re-activation of extensional structures.This research was financed by projects CGL2016-77560-C2 (C21 and C22) and PID2019-108753GB-C2 (C21 and C22), funded by MICIN/AEI/10.13039/501100011033 and by “ERDF A way of making Europe”.Peer reviewe

Characterization of Tajogaite volcanic plumes detected over the Iberian Peninsula from a set of satellite and ground-based remote sensing instrumentation

Three volcanic plumes were detected during the Tajogaite volcano eruptive activity (Canary Islands, Spain, September–December 2021) over the Iberian Peninsula. The spatiotemporal evolution of these events is characterised by combining passive satellite remote sensing and ground-based lidar and sun-photometer systems. The inversion algorithm GRASP is used with a suite of ground-based remote sensing instruments such as lidar/ ceilometer and sun-photometer from eight sites at different locations throughout the Iberian Peninsula. Satellite observations showed that the volcanic ash plumes remained nearby the Canary Islands covering a mean area of 120 ± 202 km2 during the whole period of eruptive activity and that sulphur dioxide plumes reached the Iberian Peninsula

Risk factors for unfavorable outcome and impact of early post-transplant infection in solid organ recipients with COVID-19: A prospective multicenter cohort study

The aim was to analyze the characteristics and predictors of unfavorable outcomes in solid organ transplant recipients (SOTRs) with COVID-19. We conducted a prospective observational cohort study of 210 consecutive SOTRs hospitalized with COVID-19 in 12 Spanish centers from 21 February to 6 May 2020. Data pertaining to demographics, chronic underlying diseases, transplantation features, clinical, therapeutics, and complications were collected. The primary endpoint was a composite of intensive care unit (ICU) admission and/or death. Logistic regression analyses were performed to identify the factors associated with these unfavorable outcomes. Males accounted for 148 (70.5%) patients, the median age was 63 years, and 189 (90.0%) patients had pneumonia. Common symptoms were fever, cough, gastrointestinal disturbances, and dyspnea. The most used antiviral or host-targeted therapies included hydroxychloroquine 193/200 (96.5%), lopinavir/ritonavir 91/200 (45.5%), and tocilizumab 49/200 (24.5%). Thirty-seven (17.6%) patients required ICU admission, 12 (5.7%) suffered graft dysfunction, and 45 (21.4%) died. A shorter interval between transplantation and COVID-19 diagnosis had a negative impact on clinical prognosis. Four baseline features were identified as independent predictors of intensive care need or death: advanced age, high respiratory rate, lymphopenia, and elevated level of lactate dehydrogenase. In summary, this study presents comprehensive information on characteristics and complications of COVID-19 in hospitalized SOTRs and provides indicators available upon hospital admission for the identification of SOTRs at risk of critical disease or death, underlining the need for stringent preventative measures in the early post-transplant period

Impact of the presence of heart disease, cardiovascular medications and cardiac events on outcome in COVID-19

Background: Cardiovascular risk factors and usage of cardiovascular medication are prevalent among coronavirus disease 2019 (COVID-19) patients. Little is known about the cardiovascular implications of COVID-19. The goal herein, was to evaluate the prognostic impact of having heart disease (HD) and taking cardiovascular medications in a population diagnosed of COVID-19 who required hospitalization. Also, we studied the development of cardiovascular events during hospitalization. Methods: Consecutive patients with definitive diagnosis of COVID-19 made by a positive real time- -polymerase chain reaction of nasopharyngeal swabs who were admitted to the hospital from March 15 to April 14 were included in a retrospective registry. The association of HD with mortality and with mortality or respiratory failure were the primary and secondary objectives, respectively. Results: A total of 859 patients were included in the present analysis. Cardiovascular risk factors were related to death, particularly diabetes mellitus (hazard ratio in the multivariate analysis: 1.810 [1.159– –2.827], p = 0.009). A total of 113 (13.1%) patients had HD. The presence of HD identified a group of patients with higher mortality (35.4% vs. 18.2%, p < 0.001) but HD was not independently related to prognosis; renin–angiotensin–aldosterone system inhibitors, calcium channel blockers, diuretics and beta-blockers did not worsen prognosis. Statins were independently associated with decreased mortality (0.551 [0.329–0.921], p = 0.023). Cardiovascular events during hospitalization identified a group of patients with poor outcome (mortality 31.8% vs. 19.3% without cardiovascular events, p = 0.007). Conclusions: The presence of HD is related to higher mortality. Cardiovascular medications taken before admission are not harmful, statins being protective. The development of cardiovascular events during the course of the disease is related to poor outcome

Predictive Power of the "Trigger Tool" for the detection of adverse events in general surgery: a multicenter observational validation study

Background In spite of the global implementation of standardized surgical safety checklists and evidence-based practices, general surgery remains associated with a high residual risk of preventable perioperative complications and adverse events. This study was designed to validate the hypothesis that a new “Trigger Tool” represents a sensitive predictor of adverse events in general surgery. Methods An observational multicenter validation study was performed among 31 hospitals in Spain. The previously described “Trigger Tool” based on 40 specific triggers was applied to validate the predictive power of predicting adverse events in the perioperative care of surgical patients. A prediction model was used by means of a binary logistic regression analysis. Results The prevalence of adverse events among a total of 1,132 surgical cases included in this study was 31.53%. The “Trigger Tool” had a sensitivity and specificity of 86.27% and 79.55% respectively for predicting these adverse events. A total of 12 selected triggers of overall 40 triggers were identified for optimizing the predictive power of the “Trigger Tool”. Conclusions The “Trigger Tool” has a high predictive capacity for predicting adverse events in surgical procedures. We recommend a revision of the original 40 triggers to 12 selected triggers to optimize the predictive power of this tool, which will have to be validated in future studies