22 research outputs found
THE APPLICATION OF CALCIUM CARBIDE IN THE SYNTHESIS OF D-LABELED PYRAZOLES
We proposed a synthetic approaches to 4,5-dideuteropyrazoles and regioselectively labeled 5-deuteropyrazoles. The application of CaC2-D2O mixture as a source of D2-acetylene in the reaction with in situ generated nitrile imines led to a variety of 1,3-disubstituted D2-pyrazoles in up to quantitative yields (part A). The reaction was performed in two-vessel reactor, demonstrated in the part A.Acknowledgments: We gratefully acknowledge the financial support from the Russian Science Foundation (Project β 19-73-10032)
Π‘ALCIUM CARBIDE IN THE SYNTHESIS OF D-LABELED HETEROCYCLES
We gratefully acknowledge the financial support from the Russian Science Foundation (Project β 19-73-10032)