6,728 research outputs found

    Bamboo branches out west : Zhuzhici in Xinjiang

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    Multimodal Continuous Turn-Taking Prediction Using Multiscale RNNs

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    In human conversational interactions, turn-taking exchanges can be coordinated using cues from multiple modalities. To design spoken dialog systems that can conduct fluid interactions it is desirable to incorporate cues from separate modalities into turn-taking models. We propose that there is an appropriate temporal granularity at which modalities should be modeled. We design a multiscale RNN architecture to model modalities at separate timescales in a continuous manner. Our results show that modeling linguistic and acoustic features at separate temporal rates can be beneficial for turn-taking modeling. We also show that our approach can be used to incorporate gaze features into turn-taking models.Comment: Accepted for ICMI1

    The role of influenza neuraminidase transmembrane domain on budding and virus morphology

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    Influenza A virus neuraminidase (NA), a type II transmembrane glycoprotein plays a role in the cleavage of sialic acids and facilitating the release of mature virions from the surface of infected cells. NA has also previously been shown to play a role in virion formation during influenza A virus budding, although the exact mechanisms by which NA contributes to influenza virion formation and morphology is currently unknown. Previous research has shown that mutations within the transmembrane domain (TMD) of NA can result in alteration in virion morphology, particularly in the production of filament like influenza virions. In this research project we examined if the TMD does indeed play a role in influenza virus budding and morphology. We utilised both full and partial mutations of the TMD of NA from A/WSN/33, a primarily spherical lab adapted influenza strain, with the TMD of a primarily filamentous strain A/California/09. To evaluate the effects of TMD on the morphology of a primarily spherical strain with that of filamentous strain. This study used a transfection based virus like particle (VLP) system to examine the effects of TMD alterations on morphology, utilising various biochemical and microscopy methods. Our findings show that as previously indicated mutations within the TMD do result in alterations to virion morphology, as well as showing that despite previous theories both NA and NA’s TMD may play a more active role in in budding and morphology than previously though

    The best marker for guiding the clinical management of patients with raised intracranial pressure: the RAP index or the mean pulse amplitude?

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    Raised intracranial pressure is a common problem in a variety of neurosurgical conditions including traumatic brain injury, hydrocephalus and intracranial haemorrhage. The clinical management of these patients is guided by a variety of haemodynamic, biochemical and clinical factors. However to date there is no single parameter that is used to guide clinical management of patients with raised intracranial pressure (ICP). However, the role of ICP indices, specifically the mean pulse amplitude (AMP) and RAP index [correlation coefficient (R) between AMP amplitude (A) and mean ICP pressure (P); index of compensatory reserve], as an indicator of true ICP has been investigated. Whilst the RAP index has been used both as a descriptor of neurological deterioration in TBI patients and as a way of characterising the compensatory reserve in hydrocephalus, more recent studies have highlighted the limitation of the RAP index due to the influence that baseline effect errors have on the mean ICP, which is used in the calculation of the RAP index. These studies have suggested that the ICP mean pulse amplitude may be a more accurate marker of true intracranial pressure due to the fact that it is uninfluenced by the mean ICP and, therefore, the AMP may be a more reliable marker than the RAP index for guiding the clinical management of patients with raised ICP. Although further investigation needs to be undertaken in order to fully assess the role of ICP indices in guiding the clinical management of patients with raised ICP, the studies undertaken to date provide an insight into the potential role of ICP indices to treat raised ICP proactively rather than reactively and therefore help prevent or minimise secondary brain injury

    Effects of global atmospheric perturbations on forest ecosystems: Predictions of seasonal and cumulative effects

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    The physical effects of certain large events, such as giant impacts, explosive volcanism, or combined nuclear explosions, have the potential of inducing global catastrophes in our terrestrial environment. Such highly energetic events can inject substantial quantities of material into the atmosphere. In turn, this changes the amount of sunlight reaching the Earth's surface and modifies atmospheric temperatures to produce a wide range of global effects. One consequence is the introduction of serious stresses in both plants and animals throughout the Earth's biosphere. For example, recent studies predict that forest lands, crop lands, and range lands would suffer specific physical and biological degradations if major physical and chemical disruptions occurred in our atmosphere. Forests, which cover over 4 times 10 to the 9th power hectares (4 times 10 to the 7th power sq km) of our planet, or about 3 times the area now cultivated for crops, are critical to many processes in the biosphere. Forests contribute heavily to the production of atmospheric oxygen, supply the major volume of biomass, and provide a significant percentage of plant and animal habitats

    The Privilege to Write What You Want

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    Roddy Doyle Talks to Joanna KosmalskaThis interview is part of a literature project DEC-2011/01/B/HS2/05120 financed by the National Science Centre

    Exports, Technical Progress and Productivity Growth in Chinese Manufacturing Industries

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    Theories suggesting either static or dynamic productivity gains derived from exports often assume the prior existence of a perfect market. In the presence of market failure, however, the competition effect and the resource reallocation effect of exports on productive efficiency may be greatly reduced; and there may actually be disincentives for innovation. This paper analyses the impact of exports on total factor productivity (TFP) growth in a transition economy using a panel of Chinese manufacturing industries over the period 1990-1997. TFP growth is estimated by employing a non-parametric approach and is decomposed into technical progress and efficiency change. We have not found evidence suggesting significant productivity gains at the industry level resulting from exports. Findings of the current study suggest that, for exports to generate significant positive effect on TFP growth, a well?developed domestic market and a neutral, outward-oriented policy are necessary.exports, industrial efficiency, technical progress, productivity
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