The Karolinska Institute innovation ecosystem for cancer startups: lessons learned and best practices

The Karolinska Institute's cancer startup innovation ecosystem is a dynamic network of stakeholders who collaborate to develop and commercialise innovative ideas and technologies in cancer research and treatment. This ecosystem has been successful in cultivating an environment of innovation and entrepreneurship, producing several successful startups in the cancer research and treatment space. This paper aims to provide a systematic review of the lessons learned and best practices from the Karolinska Institute innovation ecosystem for cancer startups. The review includes a comprehensive SWOT analysis , as well as insights from interviews with stakeholders from academia, industry, and government. The SWOT analysis identified several key strengths of the Karolinska Institute innovation ecosystem for cancer startups. The interview methodology for this study involved a semi-structured approach, with open questions designed to elicit detailed and nuanced responses from the participants. The Interviews and SWOT analysis identified several key of success of the Karolinska Institute innovation ecosystem for cancer startups is due to a number of key factors, including strong leadership, collaboration, funding mechanisms, supportive policies, and infrastructure. Effective leadership is required to guide the ecosystem and foster an innovation culture. Collaboration among stakeholders is critical for knowledge sharing, resource allocation, and coordination. Funding mechanisms and infrastructure are critical for supporting R&D activities and providing startups with the resources they need to grow and succeed. To protect and incentivize innovation, supportive policies such as intellectual property laws and regulatory frameworks are required. In addition, the paper discovered that incubation programmes are critical to the success of cancer startups in the Karolinska Institute innovation ecosystem. These programmes connect startups with resources, mentorship, and networks that are critical to their growth and development

Foresight for sustainable energy policy in Egypt: results from a Delphi survey

International audienceThis paper presents energy opportunities, particular areas of high potential and reflections on energy challenges in Egypt by the year 2040. Energy foresight significantly contributes in the effective review and formulation of national energy policies and strategies. In this work, 350 experts participated in real-time Delphi survey and responded to a set of structured and cross-linked questionnaires that aim to assess and provide future dimension to the energy sector in Egypt. Priorities are presented across 14 energy cluster-areas with 180 identified topics. The two-round Delphi study with an iterative process was performed to determine and measure the expectations of the different stakeholders with specific emphasis on the prospects of renewable energy and energy efficiency. The designed cross-linkages between survey components allowed the systematic pooling and convergence of knowledge in addition to the technical insights and different perspectives. About 50% of Egypt's energy demand was foresighted to be met by renewable energies around 2030. The results showed that all types of energy would not only provide economic and environmental benefits but also improve living standards. This work demonstrates that involving large diversity of expertise and different stakeholders, comprising heterogeneous groups, in foresight studies would potentiate the forecasting power, reduce the polarization effect, and enhance the reliability of the foresight exercise

Nigeria's transition to a circular economy: challenges, opportunities and future perspectives

The concept of a circular economy (CE) is a sustainable development strategy aimed at minimising waste and maximising resource efficiency. This paper explores the transition towards a circular economy in Nigeria, providing an overview of the challenges, opportunities, and future perspectives. Nigeria is rich in natural resources and has significant economic potential. However, the country faces severe environmental, economic, and social challenges that could be met with a circular economy. Although Nigeria has abundant natural resources and great economic potential, it faces many significant environmental, economic, and social challenges that must be addressed to move to a circular economy as a viable solution. The methods used in research are based on a mixed-methods research approach; the study synthesises findings from a comprehensive literature review, case studies of Nigerian businesses adopting CE practices, and insights from a SWOT analysis conducted in consultation with experts. The conclusions of the SWOT analysis, enriched by discussions with experts, form the basis for a set of targeted recommendations. These recommendations are aimed at policymakers, business leaders, and practitioners, outlining strategic actions to overcome the identified barriers and harness the opportunities inherent in a circular economy. This paper contributes to the scholarly discourse on sustainability and serves as a practical guide for other developing countries navigating the transition to a circular economy. It underscores the urgency and feasibility of adopting circular economy principles in Nigeria, highlighting the path towards a more sustainable, efficient, and economically robust future. In the study, prospects for Nigeria to benefit from include increased resource efficiency, job creation, economic diversification, and environmental sustainability if the circular economy approach were applied

Research, development and innovation in business enterprises: experience from Egypt

This paper addresses the linkages between research and development (R&D) and innovation on the one hand and the socioeconomic impact of research, development and innovation (RDI) on the other hand. More specifically, the paper suggests a two-stage methodology directed to analyse the performance of RDI in business enterprises and assess their development impact. A conceptual four-dimensional model and an integrated analytical framework were developed. This approach is complemented by the development of a statistical survey mainly designed to generate appropriate indicators for analysing the vital role of RDI in business enterprises. The survey results revealed several analytical points as well as specific imbalances of RDI system in business enterprises that need to be addressed by policymakers. Furthermore, the analytical results stress the need for Egyptian business enterprises to enhance and diversify their cooperation with other RDI-producing institutions to benefit from comparative advantages and improve the quality of RDI outputs

Integrating entrepreneurship into chemistry education - Cairo University post-graduate students' case study

Chemistry entrepreneurship is the technique of spreading knowledge about discoveries and chemical ideas to a larger audience outside of the classroom and evaluation. Graduates' ability to become job innovators with the potential to reduce unemployment and strengthen the economy is demonstrated by innovative ideas that are implemented with a social value. As a result, while attending college, chemistry students have the chance to apply what they learn in the classroom to a sustainable way of life. In this study, we have covered the breadth of classroom innovations, the "From Theory to Practice" gap, and different aspects that affect students' decisions to start and develop chemistry entrepreneurial ventures. a survey was conducted to find out more about post-graduate students' exposure to and opinions on using entrepreneurship to apply chemistry to the real world. After compiling data from an online survey consisting of 20 statements from 176 post-graduate chemistry students (Ph. D., M. Sc., and diploma) with their replies recorded on a Likert scale describing their experiences with assignments, it was possible to pinpoint areas where chemistry classes could be improved. In order to better understand how students, view the use of entrepreneurship to apply chemistry to the real world, a study was conducted to look at the breadth of creativity, the gap between thinking and doing, and the factors encouraging students to select and build a chemical pilot project

Future scenarios of green hydrogen in the MENA countries: the case of Egypt

Green hydrogen is a clean and renewable energy source that has the potential to play a major role in decarbonizing the global economy. Green hydrogen has become a promising decarbonization strategy for several industries, including transportation and manufacturing. The widespread use of green hydrogen technology still confronts several obstacles, such as high costs, a lack of infrastructure, and regulatory restrictions. The paper commences by examining the potential of green hydrogen production in MENA countries with a specific emphasis on Egypt as best practice example. It proceeds to identify the key drivers that will shape future scenarios of green hydrogen and outlines the best and worst-case scenarios for green hydrogen in MENA region by 2050. Through scenario analysis, the paper presents potential pathways for green hydrogen deployment in Egypt and the wider MENA countries, highlighting key drivers and potential barriers. According to the findings, Egypt emerges as pivotal player in driving the deployment of green hydrogen within the MENA region. The MENA region, rich in solar and wind resources and strategically located, emerges as a potent hub for green hydrogen production. Egypt, in particular, is at the forefront of this initiative, aiming to become a key exporter in the global hydrogen economy by leveraging its renewable resources, strategic projects, and conducive investment environment. The study employs a multifaceted methodology, integrating PEST analysis and identifying key drivers like renewable targets and technological advancements to assess green hydrogen’s potential in the MENA region, focusing on Egypt. It constructs best- and worst-case scenarios by 2050, utilizing these drivers to evaluate the implications of various influencing factors. In the best-case scenario, by 2050, Egypt aspires to be a pivotal player in the global green hydrogen economy, aiming for up to 8% market share. Through strategic investments, policy enhancements, and global partnerships, Egypt plans to become a major exporter, particularly to the European Union, aligning with global decarbonization goals. Comprehensive strategies are expected to drive economic prosperity, potentially increasing Egypt's GDP by $10-18 billion by 2025. Collaborations with global entities have fostered a robust infrastructure, enabling an integrated ecosystem for green hydrogen innovation and production

Circular bioeconomy in Egypt: the current state, challenges, and future directions

The concept of circular bioeconomy or bio-based circular economy is an integrated concept of circular economy and bioeconomy. In other words, it alludes to a systematic approach to economic growth that makes use of cascading biomass production from biological resources. In order to fulfil the objectives of sustainable development and the circular bioeconomy in Egypt, it is recommended that the bioeconomy be focused on as an economy of societal value in this article. It also discusses future directions and actions that can be used in this regard. This paper presents the current situation of the development of circular bioeconomy in Egypt and discuss future directions and measures that can be exploited and recommends focusing on the bioeconomy as an economy of societal value, enabling the achievement of the goals of sustainable development and the circular bioeconomy. Although there is no specific strategy for the bioeconomy, there are numerous government initiatives aiming to benefit from it in the future

Circular economy in Egypt: an overview of the current landscape and potential for growth

This paper provides an overview of the circular economy in Egypt. With the country facing significant environmental challenges, a circular economy approach can offer sustainable solutions to Egypt's environmental challenges by addressing issues like limited resources, waste generation, and a growing population in an eco-friendly and long-term perspective. This research employs a mixed-methods approach, including a literature review, surveys, and consultations with key stakeholders. The analysis reveals that although there are numerous challenges to establishing a circular economy in Egypt, such as limited understanding, insufficient government backing, and inadequate infrastructure, there are also opportunities, such as increasing demand for eco-friendly goods and services, as well as a receptive business environment. The paper recommends various policy and practical interventions to overcome these barriers and capitalize on these opportunities, including increasing awareness and understanding of the circular economy, developing supportive programs and regulations, investing in infrastructure and technology, and fostering stakeholder collaboration. This paper provides valuable insights into the potential for a circular economy in Egypt and the steps that can be taken to create a more sustainable future for the country. As such, it will interest policymakers, researchers, and practitioners working in the sustainability and environmental management field. The successful implementation of a circular economy in Egypt will require collective efforts from stakeholders to promote long-term sustainability and environmental stewardship

Burnout among surgeons before and during the SARS-CoV-2 pandemic: an international survey

Background: SARS-CoV-2 pandemic has had many significant impacts within the surgical realm, and surgeons have been obligated to reconsider almost every aspect of daily clinical practice. Methods: This is a cross-sectional study reported in compliance with the CHERRIES guidelines and conducted through an online platform from June 14th to July 15th, 2020. The primary outcome was the burden of burnout during the pandemic indicated by the validated Shirom-Melamed Burnout Measure. Results: Nine hundred fifty-four surgeons completed the survey. The median length of practice was 10 years; 78.2% included were male with a median age of 37 years old, 39.5% were consultants, 68.9% were general surgeons, and 55.7% were affiliated with an academic institution. Overall, there was a significant increase in the mean burnout score during the pandemic; longer years of practice and older age were significantly associated with less burnout. There were significant reductions in the median number of outpatient visits, operated cases, on-call hours, emergency visits, and research work, so, 48.2% of respondents felt that the training resources were insufficient. The majority (81.3%) of respondents reported that their hospitals were included in the management of COVID-19, 66.5% felt their roles had been minimized; 41% were asked to assist in non-surgical medical practices, and 37.6% of respondents were included in COVID-19 management. Conclusions: There was a significant burnout among trainees. Almost all aspects of clinical and research activities were affected with a significant reduction in the volume of research, outpatient clinic visits, surgical procedures, on-call hours, and emergency cases hindering the training. Trial registration: The study was registered on clicaltrials.gov "NCT04433286" on 16/06/2020