31 research outputs found

    Coastal and Ocean Modeling Testbed (COMT)

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    Mobile Grocery Stores for Rural Communities

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    On January 19, 2018, Cowley County was contacted by a representative from Sunflower Foundation with an amazing opportunity. The funder had been in contact with Honor Capital, LLC, a veteran-owned private equity firm with the mission to build and operate grocery stores in underserved areas. While much of their work has been in urban settings, Honor Capital, LLC has a desire to tackle the very unique challenge of RURAL food deserts. They recently received funding from out of state to pilot the concept of a mobile grocery truck in rural Kansas. They wish to use the recently built Save-a-Lot store in Winfield to service surrounding towns without grocery stores. Sunflower Foundation offered to provide a grant to a local non-profit that might support the role of grocery/healthy food liaisons (paid positions) in the small communities where the truck wishes to stop. The liaisons would serve as a critical connector between the grocery store and the residents – surveying community wants/needs, figuring out best ordering system for people, promoting and publicizing the grocery truck with all forms of media including coffee shop talk and social media, perhaps even figuring out healthy food cooking demos or innovative ideas like pre-packaged meal boxes. Of critical importance is the work of local champions. How can rural communities mobilize themselves to be ready? Partnerships are key as well as the willingness to try, fail and persevere. This project reflects how strengthening communities with strong partnerships can lead to strengthened health for communities. This presentation emphasizes the importance of partnerships and being willing to try, fail and persevere. Cowley County shares data about its rural communities and existing community partnerships to help support this project. Residents in rural communities accept that they have to leave their community for many consumer goods and services. The concept of a mobile rural grocery store model strengthens communities and strengthens health

    Pecan crop load management

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    The Oklahoma Cooperative Extension Service periodically issues revisions to its publications. The most current edition is made available. For access to an earlier edition, if available for this title, please contact the Oklahoma State University Library Archives by email at [email protected] or by phone at 405-744-6311

    Prospectus, December 6, 1974

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    OTHERS DISAGREE: STAERKEL: \u27DAY CARE JUST A CONVENIENCE\u27; Student Government Up For Grabs Again; P/C Model For Therapeutic Rec; Gunji Coordinator For Recognition Awards Selection; Our First Report On A Cape Kennedy Launch; Pre-Registration Helps Everyone; UPC: Consumer Aid Or Just A bother?; Fool Killer Does Wonder, The Pips Fool Mother Nature; Where Are We? A Few Facts On The New Signs; Prospectus Gets Bomb Threat, Caller \u27Disturbed\u27; Cyclowski Is First Fast Freddy Repeat; getting around day care; The Short Circuit; A Column By And For Women; getting the shaft; summary of report on possible child care services at parkland college; letters; High School Visitation Week; The Five Snow Queen Finalists; All Set For StuGo Election; Classified Ads; Cobras Notch Two Wins; Parkland-Rend Lake; Parkland-Wabash Valley; IM Basketball Starts Tomorrow; High Rollers Squeak Past BMF For IM Championship; Electronic Music Made Easy; 528 Earn Spot On Honors List; Author Richard Farina\u27s Latest \u27Interesting Despite The Flaws\u27; Parkland Events; Callboard; Europe Still Available At Low Cost; IM Basketball Schedulehttps://spark.parkland.edu/prospectus_1974/1001/thumbnail.jp

    Factors deterring schools from mixed attainment teaching practice

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    Mixed-attainment teaching has strong support from research and yet English schools are far more likely to teach students in ‘ability’ groups. Although research has considered some of the specific benefits of mixed-attainment grouping, there has been little attention to the reasons schools avoid it. This article explores data from the pilot and recruitment phases of a large-scale study into grouping practices and seeks to identify reasons for the low rate of mixed attainment grouping in English secondary schools. We report on our struggle to recruit schools, and explore the different explanations provided by teachers as to why mixed attainment practice is seen as problematic. The difficulties are characterised as a vicious circle where schools are deterred by a paucity of exemplars and resources and the educational climate is characterised as fearful, risk-averse and time-poor. Suggestions are made as to strategies to support schools in taking up mixed attainment practices

    Finishing the euchromatic sequence of the human genome

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    The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

    Bi-allelic Loss-of-Function CACNA1B Mutations in Progressive Epilepsy-Dyskinesia.

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    The occurrence of non-epileptic hyperkinetic movements in the context of developmental epileptic encephalopathies is an increasingly recognized phenomenon. Identification of causative mutations provides an important insight into common pathogenic mechanisms that cause both seizures and abnormal motor control. We report bi-allelic loss-of-function CACNA1B variants in six children from three unrelated families whose affected members present with a complex and progressive neurological syndrome. All affected individuals presented with epileptic encephalopathy, severe neurodevelopmental delay (often with regression), and a hyperkinetic movement disorder. Additional neurological features included postnatal microcephaly and hypotonia. Five children died in childhood or adolescence (mean age of death: 9 years), mainly as a result of secondary respiratory complications. CACNA1B encodes the pore-forming subunit of the pre-synaptic neuronal voltage-gated calcium channel Cav2.2/N-type, crucial for SNARE-mediated neurotransmission, particularly in the early postnatal period. Bi-allelic loss-of-function variants in CACNA1B are predicted to cause disruption of Ca2+ influx, leading to impaired synaptic neurotransmission. The resultant effect on neuronal function is likely to be important in the development of involuntary movements and epilepsy. Overall, our findings provide further evidence for the key role of Cav2.2 in normal human neurodevelopment.MAK is funded by an NIHR Research Professorship and receives funding from the Wellcome Trust, Great Ormond Street Children's Hospital Charity, and Rosetrees Trust. E.M. received funding from the Rosetrees Trust (CD-A53) and Great Ormond Street Hospital Children's Charity. K.G. received funding from Temple Street Foundation. A.M. is funded by Great Ormond Street Hospital, the National Institute for Health Research (NIHR), and Biomedical Research Centre. F.L.R. and D.G. are funded by Cambridge Biomedical Research Centre. K.C. and A.S.J. are funded by NIHR Bioresource for Rare Diseases. The DDD Study presents independent research commissioned by the Health Innovation Challenge Fund (grant number HICF-1009-003), a parallel funding partnership between the Wellcome Trust and the Department of Health, and the Wellcome Trust Sanger Institute (grant number WT098051). We acknowledge support from the UK Department of Health via the NIHR comprehensive Biomedical Research Centre award to Guy's and St. Thomas' National Health Service (NHS) Foundation Trust in partnership with King's College London. This research was also supported by the NIHR Great Ormond Street Hospital Biomedical Research Centre. J.H.C. is in receipt of an NIHR Senior Investigator Award. The research team acknowledges the support of the NIHR through the Comprehensive Clinical Research Network. The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR, Department of Health, or Wellcome Trust. E.R.M. acknowledges support from NIHR Cambridge Biomedical Research Centre, an NIHR Senior Investigator Award, and the University of Cambridge has received salary support in respect of E.R.M. from the NHS in the East of England through the Clinical Academic Reserve. I.E.S. is supported by the National Health and Medical Research Council of Australia (Program Grant and Practitioner Fellowship)

    Sharing Water with Nature: Insights on Environmental Water Allocation from a Case Study of the Murrumbidgee Catchment, Australia

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    Human use of freshwater resources has placed enormous stress on aquatic ecosystems in many regions of the world. At one time, this was considered an acceptable price to pay for economic growth and development. Nowadays, however, many societies are seeking a better balance between healthy aquatic ecosystems and viable economies. Unfortunately, historically, water allocation systems have privileged human uses over the environment. Thus, jurisdictions seeking to ensure that adequate water is available for the environment must typically deal with the fact that economies and communities have become dependent on water. Additionally, they must often layer institutions for environmental water allocation (EWA) on top of already complex institutional systems. This paper explores EWA in a jurisdiction – New South Wales (NSW), Australia – where water scarcity has become a priority. Using an in-depth case study of EWA in the Murrumbidgee catchment, NSW, we characterise the NSW approach to EWA with the goal of highlighting the myriad challenges encountered in EWA planning and implementation. Sharing water between people and the environment, we conclude, is much more than just a scientific and technical challenge. EWA in water-scarce regions involves reshaping regional economies and societies. Thus, political and socio-economic considerations must be identified and accounted for from the outset of planning and decision-making processes
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