The Impact of the Exploring Computer Science Instructional Model in Chicago Public Schools

As part of the Taste of Computing project, the Exploring Computer Science (ECS) instructional model has been expanded to many high schools in the Chicago Public Schools system. We report on initial outcomes showing that students value the ECS course experience, resulting in increased awareness of and interest in the field of computer science. We compare these results by race and gender. The data provide a good basis for exploring the impact of meaningful computer science instruction on students from groups underrepresented in computing; of several hundred students surveyed, nearly half were female, and over half were Hispanic or African-American

The Impact of Meaningful High School Computer Science Experiences in the Chicago Public Schools

We report on initial outcomes of the Taste of Computing project, under which a meaningful computer science course has been initiated in many high schools of the Chicago Public Schools system. Surveys of students have shown that they attribute high value to the course and have experienced increases in their understanding and interest regarding the computing field. Data was also collected from teachers participating in professional development regarding their preparation and confidence in teaching the new course. We report on the strengths of various survey responses and their relationships, and we compare student responses by race and gender. The data provide a good basis for exploring the impact of meaningful computer science instruction on students from groups underrepresented in computing; of several hundred students surveyed, nearly half were female, and over half were Hispanic or African-American

Deregulation of cyclin E in human cells interferes with prereplication complex assembly

Deregulation of cyclin E expression has been associated with a broad spectrum of human malignancies. Analysis of DNA replication in cells constitutively expressing cyclin E at levels similar to those observed in a subset of tumor-derived cell lines indicates that initiation of replication and possibly fork movement are severely impaired. Such cells show a specific defect in loading of initiator proteins Mcm4, Mcm7, and to a lesser degree, Mcm2 onto chromatin during telophase and early G1 when Mcm2–7 are normally recruited to license origins of replication. Because minichromosome maintenance complex proteins are thought to function as a heterohexamer, loading of Mcm2-, Mcm4-, and Mcm7-depleted complexes is likely to underlie the S phase defects observed in cyclin E–deregulated cells, consistent with a role for minichromosome maintenance complex proteins in initiation of replication and fork movement. Cyclin E–mediated impairment of DNA replication provides a potential mechanism for chromosome instability observed as a consequence of cyclin E deregulation

Evaluation of the IMPACTS Computer Science Presentations

Recent computer science enrollments have shown positive trends. However, these trends are not evenly distributed by gender and race. Efforts to recruit underrepresented students should focus on providing information that demystifies the field of computer science. This paper reports on such an effort to inform underrepresented high school students about the field and its diversity. The results suggest that increasing awareness in an enjoyable format can increase student interest in pursuing computer science. These results can provide guidance about ways to encourage students to take high school computer science classes as motivation and preparation for college-level computer science

Do Hypnosis and Mindfulness Practices Inhabit a Common Domain? Implications for Research, Clinical Practice, and Forensic Science

Hypnosis and mindfulness practices provide clinicians with two viable yet distinct methods, or more accurately families of methods, for increasing well-being and ameliorating problems in living. In this article, we compare and contrast hypnotic and mindfulness interventions, address the question of whether they inhabit a common domain, describe how they may be combined to advantage, and discuss clinical and research implications. We contend that hypnosis and mindfulness inhabit a common, albeit broad, domain of suggestive approaches. However, we also argue that meaningful differences exist that are particularly salient and consequential in the forensic arena

CS as a Graduation Requirement: Catalyst for Systemic Change

Since President Obama\u27s announcement of the Computer Science for All Initiative in 2016, there has been a surge in the number of districts that are planning for or newly implementing computer science (CS) offerings at their schools. Chicago Public Schools (CPS) is the first large school district to have adopted Computer Science as a high school graduation requirement, taking this significant step along the path towards systemic change. The foundation was laid eight years ago when an informal alliance was formed between a CPS high school CS teacher, a CPS administrator, and three university computer scientists

Coordinated Spindle Assembly and Orientation Requires Clb5p-Dependent Kinase in Budding Yeast

The orientation of the mitotic spindle along a polarity axis is critical in asymmetric cell divisions. In the budding yeast, Saccharomyces cerevisiae, loss of the S-phase B-type cyclin Clb5p under conditions of limited cyclin-dependent kinase activity (cdc28-4 clb5Δ cells) causes a spindle positioning defect that results in an undivided nucleus entering the bud. Based on time-lapse digital imaging microscopy of microtubules labeled with green fluorescent protein fusions to either tubulin or dynein, we observed that the asymmetric behavior of the spindle pole bodies during spindle assembly was lost in the cdc28-4 clb5Δ cells. As soon as a spindle formed, both poles were equally likely to interact with the bud cell cortex. Persistent dynamic interactions with the bud ultimately led to spindle translocation across the bud neck. Thus, the mutant failed to assign one spindle pole body the task of organizing astral microtubules towards the mother cell. Our data suggest that Clb5p-associated kinase is required to confer mother-bound behavior to one pole in order to establish correct spindle polarity. In contrast, B-type cyclins, Clb3p and Clb4p, though partially redundant with Clb5p for an early role in spindle morphogenesis, preferentially promote spindle assembly

Chicago Alliance For Equity in Computer Science

CAFECS is committed to ensuring that all students in Chicago participate in engaging, relevant, and rigorous computing experiences by addressing problems of practice through research and development that increases opportunities for all students to pursue computing pathways and prepares all students for the future of work