88 research outputs found
Durable proteo-hybrid vesicles for the extended functional lifetime of membrane proteins in bionanotechnology
Plantas vasculares da região do Parque Estadual Cristalino, norte de Mato Grosso, Brasil
Therapeutic Nanoreactors: Combining Chemistry and Biology in a Novel Triblock Copolymer Drug Delivery System
Triblock copolymeric nanoreactors are introduced as an alternative for liposomes as encapsulating carrier for prodrug activating enzymes. Inosine−adenosine−guanosine preferring nucleoside hydrolase of Trypanosoma vivax, a potential prodrug activating enzyme, was encapsulated in nanometer-sized vesicles constructed of poly(2-methyloxazoline)-block-poly(dimethylsiloxane)-block-(2-methyloxazoline) triblock copolymers. The nanoreactor is functionalized by incorporation of bacterial porins, OmpF or Tsx, in the reactor wall. Efficient cleavage of three natural substrates and one prodrug, 2-fluoroadenosine, by the nanoreactors was demonstrated
PRO3 TREATMENT PATTERNS AND OUTCOMES ASSOCIATED WITH THE USE OF PONATINIB IN CLINICAL PRACTICE: A QUALITATIVE SYSTEMATIC LITERATURE REVIEW
Unloading the right ventricle in the crest syndrome variant of progressive systemic sclerosis (scleroderma)
- …