Normal soaking extraction (NSE) of rotenone from Derris elliptica

Derris elliptica or the tuba plant contains rotenone, bio-active compound known that has the potential to be used as bio-pesticide. Bio-pesticide is the best-known alternative bio-pesticide which has the potential to replace the use of conventional pesticides, as it is more environmentally friendly. The main objective of the paper is to obtain the best extraction solvent for optimizing the yield in rotenone extraction. Rotenone was extracted from Derris root using three different parts of roots and three types of solvent in Normal Soaking Extraction (NSE). The types of Derris roots are: (1) Fine root (2) Coarse root (3) Stem. The three types of solvent system are: (1) Acetone 95 % (v/v), (2) Chloroform 99.9 % (v/v) and (3) a mixture of ethanol: H2O (9:1) added with oxalic acid (1mg/ml). The liquid crude extracts were further cleaned up to remove the fine debris of roots. The presence of rotenone was confirmed using qualitative analysis Thin Layer Chromatography (TLC) and thereupon the determination of rotenone content was carried out using High Performance Liquid Chromatography (HPLC). From the results obtained, it was found that the Normal Soaking Extraction (NSE) using acetone 95 % (v/v) was the best method to extract the highest yield of rotenone; 1.14 % (w/w)

SoC-based biomedical embedded system design of arrhythmia detector

Arrhythmia is an irregular heartbeat where the blood may not be delivered effectively throughout the body and cause sudden cardiac arrest (SCA). Immediate treatment is required to prevent SCA. However, most of the existing electrocardiogram (ECG) monitoring devices are bulky, cost expensive and lack arrhythmia detection and classification system. This paper proposes a front-end on-board graphical interface design of System-on-Chip (SoC) based arrhythmia detector which can be used as a first screening device for cardiac disease patient. The system consists of a knowledge-based arrhythmia classifier which is able to identify three types of arrhythmias which are ventricular fibrillation (VF), premature ventricular contractions (PVCs) and second-degree atrioventricular (AV) block. The system has been evaluated and benchmarked with ECG data from MIT-BIH arrhythmia database. The results show that its accuracy is up to 99.25% with a computation time of 6.385 seconds. It is highly portable and relatively inexpensive for installation in small clinics and home monitoring

Level of Service for Pedestrian Movement towards the Performance of Passenger Information in Public Transport Stations in Klang Valley

Rapid growth in car ownership in Malaysia plays a major role to traffic congestion. Hence, public transportation is crucial to cater the residents in high-density area especially in Klang Valley. Signage information in public transport station is one of an important passenger information system. Poor placement of sign information will decrease the efficiency of passenger flow and caused congestion in the station. Passenger information system is very useful for trip planning and decision making. Therefore, it is interesting to study the performance of passenger information system in focusing the movement behavior of pedestrian at non-peak period. Thus, the study on pedestrian movement during non-peak period on weekdays and weekends in mass transit stations and bus transit stations in Klang Valley was carried out by using video observation. The observation of the pedestrian movement was made in Mass Transit Station 1 in the middle of Kuala Lumpur and Mass Transit Station 2 in southern of Kuala Lumpur. The other site was focused at Bus Transit Station 1 in Putrajaya and Bus Transit Station 2 in Kajang. Findings shown that Mass Transit Station 1 having the best facility in terms of passenger information which the level of service obtained is LOS A, while the lowest level of service which is LOS E was obtained in Bus Transit Station 2

Fire Propagation Performance of Intumescent Fire Protective Coatings Using Eggshells as a Novel Biofiller

This paper aims to synthesize and characterize an effective intumescent fire protective coating that incorporates eggshell powder as a novel biofiller. The performances of thermal stability, char formation, fire propagation, water resistance, and adhesion strength of coatings have been evaluated. A few intumescent flame-retardant coatings based on these three ecofriendly fire retardant additives ammonium polyphosphate phase II, pentaerythritol and melamine mixed together with flame-retardant fillers, and acrylic binder have been prepared and designed for steel. The fire performance of the coatings has conducted employing BS 476: Part 6-Fire propagation test. The foam structures of the intumescent coatings have been observed using field emission scanning electron microscopy. On exposure, the coated specimens’ B, C, and D had been certified to be Class 0 due to the fact that their fire propagation indexes were less than 12. Incorporation of ecofriendly eggshell, biofiller into formulation D led to excellent performance in fire stopping (index value, (I)=4.3) and antioxidation of intumescent coating. The coating is also found to be quite effective in water repellency, uniform foam structure, and adhesion strength

Corrosion inhibition effect of the synthetized 2-butyl-3-({4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-1,3-diazaspiro[4.4]non-1-en-4-one drug on CS in 1 M HCl electrolyte: electrochemical, spectroscopic and theoretical investigations

The synthesized IRBESARTAN drug, namely, 2-butyl-3-({4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-1,3-diazaspiro[4.4]non-1-en-4-one (IRBESARTAN) was prepared and characterized using NMR spectroscopy. The obtained product was evaluated by electrochemical and spectroscopic measurements as an anticorrosion for carbon steel (CS) in 1.0 M HCl electrolyte. It is obtained that the IRBESARTAN reacts as a good and mixed-type inhibitor, where its performance rises with its concentration and immersion time, which offered inhibition efficiency up to 94.02 % according to EIS measurements. In addition, the temperature influence on the CS dissolution rate was considered without and with IRBESARTAN at the optimum concentration. It is indicated that it is performant at high temperature. Additionally, the thermodynamic and activation data discovered that the IRBESARTAN particles adsorption on the CS area is an endothermic procedure. Indeed, its action obeys to the Langmuir model, relating both physical and chemical actions. The scanning electron microscopy (SEM) analysis demonstrated the construction of a defensive deposit, confirming the electrochemical findings. Finally, the DFT calculations and MD simulation explain the mode of the IRBESARTAN adsorption, and confirm the obtained experimental results

Molecular Analysis Of Cyp21 Gene In Patients Presenting With Ambiguous Genitalia.

Congenital adrenal hyperplasia (CAH) is a group of autosomal recessive disorders of adrenal steroidogenesis

Study of 5.8 GHz Band-Stop Frequency Selective Surface (FSS)

This paper presents the study of 5.8 GHz frequency selective surface (FSS) acts as a band stop to eliminate unwanted radiation signal at 5.8GHz. The FSS was designed using computer simulation technology (CST) Microwave Studio software. The paper shows the comparison of square loop, octagon loop and hexagon loop of Band stop FSS (BSFSS) performance at 5.8 GHz. Besides, the BSFSS design using four different type of dielectric substrate such as FR-4, TLY-5, Roger RT5870 and Roger RT5880 were compared. The results obviously show that the Rogers RY5880 has the attenuation -44.72 dB.  The fabricated FSS were measured by using free space technique with two horn antennas connected to performance network analyzer (PNA). The measured and simulated results were compared. The results show that the square loop FSS structure have the better attenuation -26.76 dB (simulated) and -38.34 dB (measured) at 5.8 GHz