4,726 research outputs found
The development of technology required for the successful deposition of aluminum alloys and beryllium
Development of technology for electrodeposition of aluminum alloys and berylliu
Research and development of magnesium/aluminum electroforming process for solar concentrators Final report, 13 May 1966 - 10 May 1967
Magnesium and aluminum electroforming process for solar concentrator
A Mobile Geo-Communication Dataset for Physiology-Aware DASH in Rural Ambulance Transport
Use of telecommunication technologies for remote, continuous monitoring of
patients can enhance effectiveness of emergency ambulance care during transport
from rural areas to a regional center hospital. However, the communication
along the various routes in rural areas may have wide bandwidth ranges from 2G
to 4G; some regions may have only lower satellite bandwidth available.
Bandwidth fluctuation together with real-time communication of various clinical
multimedia pose a major challenge during rural patient ambulance transport.;
AB@The availability of a pre-transport route-dependent communication bandwidth
database is an important resource in remote monitoring and clinical multimedia
transmission in rural ambulance transport. Here, we present a geo-communication
dataset from extensive profiling of 4 major US mobile carriers in Illinois,
from the rural location of Hoopeston to the central referral hospital center at
Urbana. In collaboration with Carle Foundation Hospital, we developed a
profiler, and collected various geographical and communication traces for
realistic emergency rural ambulance transport scenarios. Our dataset is to
support our ongoing work of proposing "physiology-aware DASH", which is
particularly useful for adaptive remote monitoring of critically ill patients
in emergency rural ambulance transport. It provides insights on ensuring higher
Quality of Service (QoS) for most critical clinical multimedia in response to
changes in patients' physiological states and bandwidth conditions. Our dataset
is available online for research community.Comment: Proceedings of the 8th ACM on Multimedia Systems Conference
(MMSys'17), Pages 158-163, Taipei, Taiwan, June 20 - 23, 201
An intelligent training system for payload-assist module deploys
An autonomous intelligent training system which integrates expert system technology with training/teaching methodologies is described. The Payload-Assist Module Deploys/Intelligent Computer-Aided Training (PD/ICAT) system has, so far, proven to be a potentially valuable addition to the training tools available for training Flight Dynamics Officers in shuttle ground control. The authors are convinced that the basic structure of PD/ICAT can be extended to form a general architecture for intelligent training systems for training flight controllers and crew members in the performance of complex, mission-critical tasks
Indian monsoon variability on millennial-orbital timescales
The Indian summer monsoon (ISM) monsoon is critical to billions of people living in the region. Yet, significant debates remain on primary ISM drivers on millennial-orbital timescales. Here, we use speleothem oxygen isotope (δ18O) data from Bittoo cave, Northern India to reconstruct ISM variability over the past 280,000 years. We find strong coherence between North Indian and Chinese speleothem δ18O records from the East Asian monsoon domain, suggesting that both Asian monsoon subsystems exhibit a coupled response to changes in Northern Hemisphere summer insolation (NHSI) without significant temporal lags, supporting the view that the tropical-subtropical monsoon variability is driven directly by precession-induced changes in NHSI. Comparisons of the North Indian record with both Antarctic ice core and sea-surface temperature records from the southern Indian Ocean over the last glacial period do not suggest a dominant role of Southern Hemisphere climate processes in regulating the ISM variability on millennial-orbital timescales
Optimal rate assignment strategy to minimize average waiting time in wireless networks
In a wireless network that supports multiple flows, allocation of bandwidth resource among the flows is one of the critical problems. Different allocation strategies have been developed based on different optimization objectives. Unfortunately, these objectives may not reflect directly the time needed for a flow to transmit what it wants. In this paper, we define a new objective, average waiting time, that reflects the average time needed for the flows to finish their transmissions. For small networks, we develop an optimal scheme that minimizes the average waiting time. We extend the mechanism for general networks, and simulation results show that it can significantly reduce the average waiting time when compared with other existing mechanisms. © 2011 IEEE.published_or_final_versionThe 2011 IEEE Vehicular Technology Conference (VTC Fall), San Francisco, CA., 5-8 September 2011. In IEEEVTS Vehicular Technology Conference Proceedings, 2011, p. 1-
Genomic and Transcriptomic Alterations Associated with STAT3 Activation in Head and Neck Cancer.
BackgroundHyperactivation of STAT3 via constitutive phosphorylation of tyrosine 705 (Y705) is common in most human cancers, including head and neck squamous carcinoma (HNSCC). STAT3 is rarely mutated in cancer and the (epi)genetic alterations that lead to STAT3 activation are incompletely understood. Here we used an unbiased approach to identify genomic and epigenomic changes associated with pSTAT3(Y705) expression using data generated by The Cancer Genome Atlas (TCGA).Methods and findingsMutation, mRNA expression, promoter methylation, and copy number alteration data were extracted from TCGA and examined in the context of pSTAT3(Y705) protein expression. mRNA expression levels of 1279 genes were found to be associated with pSTAT3(705) expression. Association of pSTAT3(Y705) expression with caspase-8 mRNA expression was validated by immunoblot analysis in HNSCC cells. Mutation, promoter hypermethylation, and copy number alteration of any gene were not significantly associated with increased pSTAT3(Y705) protein expression.ConclusionsThese cumulative results suggest that unbiased approaches may be useful in identifying the molecular underpinnings of oncogenic signaling, including STAT3 activation, in HNSCC. Larger datasets will likely be necessary to elucidate signaling consequences of infrequent alterations
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