The gravity of magnetic stresses and energy

In the framework of designing laboratory tests of relativistic gravity, we investigate the gravitational field produced by the magnetic field of a solenoid. Observing this field might provide a mean of testing whether stresses gravitate as predicted by Einstein's theory. A previous study of this problem by Braginsky, Caves and Thorne predicted that the contribution to the gravitational field resulting from the stresses of the magnetic field and of the solenoid walls would cancel the gravitational field produced by the mass-energy of the magnetic field, resulting in a null magnetically-generated gravitational force outside the solenoid. They claim that this null result, once proved experimentally, would demonstrate the stress contribution to gravity. We show that this result is incorrect, as it arises from an incomplete analysis of the stresses, which neglects the axial stresses in the walls. Once the stresses are properly evaluated, we find that the gravitational field outside a long solenoid is in fact independent of Maxwell and material stresses, and it coincides with the newtonian field produced by the linear mass distribution equivalent to the density of magnetic energy stored in a unit length of the solenoid. We argue that the gravity of Maxwell stress can be directly measured in the vacuum region inside the solenoid, where the newtonian noise is absent in principle, and the gravity generated by Maxwell stresses is not screened by the negative gravity of magnetic-induced stresses in the solenoid walls.Comment: 10 pages, final version accepted for publication in PR

Study of RPC gas mixtures for the ARGO-YBJ experiment

The ARGO-YBJ experiment consists of a RPC carpet to be operated at the Yangbajing laboratory (Tibet, P.R. China), 4300 m a.s.l., and devoted to the detection of showers initiated by photon primaries in the energy range 100 GeV - 20 TeV. The measurement technique, namely the timing on the shower front with a few tens of particles, requires RPC operation with 1 ns time resolution, low strip multiplicity, high efficiency and low single counting rate. We have tested RPCs with many gas mixtures, at sea level, in order to optimize these parameters. The results of this study are reported.Comment: 6 pages, 3 figures. To be published in Nucl. Instr. Meth. A, talk given at the "5th International Workshop on RPCs and Related Detectors", Bari (Italy) 199

A lower limit for Newtonian-noise models of the Einstein Telescope

The Einstein Telescope (ET) is a proposed third-generation gravitational-wave (GW) underground observatory. It will have greatly increased sensitivity compared to current GW detectors, and it is designed to extend the observation band down to a few Hz. At these frequencies, a major limitation of the ET sensitivity is predicted to be due to gravitational fluctuations produced by the environment, most importantly by the seismic field, which give rise to the so-called Newtonian noise (NN). Accurate models of ET NN are crucial to assess the compatibility of an ET candidate site with the ET sensitivity target also considering a possible reduction in NN by noise cancellation. With NN models becoming increasingly complex as they include details of geology and topography, it is crucial to have tools to make robust assessments of their accuracy. For this purpose, we derive a lower bound on seismic NN spectra, which is weakly dependent on geology and properties of the seismic field. As a first application, we use the lower limit to compare it with NN estimates recently calculated for the Sardinia and Euregio Meuse-Rhine (EMR) candidate sites. We find the utility of the method, which shows an inconsistency with the predictions for the EMR site, which indicates that ET NN models require further improvement

THE PAST AND THE FUTURE OF DIRECT SEARCH OF GW FROM PULSARS IN THE ERA OF GW ANTENNAS

In this paper we will give an overview of the past and present status of Gravitational Wave (GW) research associated with pulsars, taking into account the target sensitivity achieved from interferometric laser GW antennas such as Tama, Geo, Ligo and Virgo. We will see that the upper limits obtained with searches for periodic GW begin to be astrophysically interesting by imposing non-trivial constraints on the structure and evolution of the neutron stars. We will give prospects for the future detection of pulsar GW signals, with Advanced Ligo and Advanced Virgo and future enhanced detectors, e.g. the Einstein Telescope

THE PAST AND THE FUTURE OF DIRECT SEARCH OF GW FROM PULSARS IN THE ERA OF GW ANTENNAS

In this paper we will give an overview of the past and present status of Gravitational Wave (GW) research associated with pulsars, taking into account the target sensitivity achieved from interferometric laser GW antennas such as Tama, Geo, Ligo and Virgo. We will see that the upper limits obtained with searches for periodic GW begin to be astrophysically interesting by imposing non-trivial constraints on the structure and evolution of the neutron stars. We will give prospects for the future detection of pulsar GW signals, with Advanced Ligo and Advanced Virgo and future enhanced detectors, e.g. the Einstein Telescope

Positron localization effects on the Doppler broadening of the annihilation line: Aluminum as a case study

The coincidence Doppler broadening (CDB) technique is widely used to measure one-dimensional momentum distributions of annihilation photons, with the aim of obtaining information on the chemical environment of open-volume defects. However, the quantitative analysis of CDB spectra needs to include also purely geometrical effects. A demonstration is given here, on the basis of CDB spectra measured in quenched and in deformed pure aluminum. The comparison of the experimental results with ab initio computations shows that the observed differences come from the difference in free volume seen by positrons trapped in quenched-in vacancies or in vacancylike defects associated to dislocations. The computation reproduces accurately all details of CDB spectra, including the peak near the Fermi break, which is due to the zero-point motion of the confined positron.Peer reviewe

RNA structure drives interaction with proteins

The combination of high-throughput sequencing and in vivo crosslinking approaches leads to the progressive uncovering of the complex interdependence between cellular transcriptome and proteome. Yet, the molecular determinants governing interactions in protein-RNA networks are not well understood. Here we investigated the relationship between the structure of an RNA and its ability to interact with proteins. Analysing in silico, in vitro and in vivo experiments, we find that the amount of double-stranded regions in an RNA correlates with the number of protein contacts. This relationship —which we call structure-driven protein interactivity— allows classification of RNA types, plays a role in gene regulation and could have implications for the formation of phase-separated ribonucleoprotein assemblies. We validate our hypothesis by showing that a highly structured RNA can rearrange the composition of a protein aggregate. We report that the tendency of proteins to phase-separate is reduced by interactions with specific RNAs

children: differentiation using diffusion-weighted magnetic resonance imaging

Purpose To evaluate differences in magnetic resonance imaging (MRI) appearance between infantile hemangiomas and rhabdomyosarcomas of the orbit in pediatric patients using diffusion-weighted imaging. Methods A multicenter retrospective review of MRIs of pediatric patients with infantile hemangiomas and rhabdomyosarcomas of the orbit was performed. MRI examinations from a total of 21 patients with infantile hemangiomas and 12 patients with rhabdomyosarcomas of the orbit were independently reviewed by two subspecialty board-certified neuroradiologists masked to the diagnosis. A freehand region of interest was placed in the mass to obtain the mean apparent diffusion coefficient (ADC) value of the mass as well as within the medulla to obtain a ratio of the ADC mass to the medulla. A t test was used to compare mean ADC and ADC ratios between the two groups. Receiver operating characteristic analysis was performed to determine ADC value and ADC ratio thresholds for differentiation of infantile hemangioma and rhabdomyosarcoma. Results There was a statistically significant difference in the mean ADC value of infantile hemangiomas compared to rhabdomyosarcomas (1527 × 10−6 mm2/s vs 782 × 10−6 mm2/s; P = 0.0001) and the ADC ratio of the lesion to the medulla (1.77 vs 0.92; P = 0.0001). An ADC threshold of <1159 × 10−6 mm2/sec and an ADC ratio of <1.38 differentiated rhabdomyosarcoma from infantile hemangioma (sensitivity 100% and 100%; specificity 100% and 100%) with area under the curve of 1.0 and 1.0, respectively. Conclusions In conjunction with conventional MRI sequences, ADC values obtained from diffusion-weighted MRI are useful to differentiate orbital infantile hemangiomas from rhabdomyosarcomas in pediatric patients

The Aladin2 experiment: sensitivity study

Aladin2 is an experiment devoted to the first measurement of variations of Casimir energy in a rigid body. The main short-term scientific motivation relies on the possibility of the first demonstration of a phase transition influenced by vacuum fluctuations while, in the long term and in the mainframe of the cosmological constant problem, it can be regarded as the first step towards a measurement of the weight of vacuum energy. In this paper, after a presentation of the guiding principle of the measurement, the experimental apparatus and sensitivity studies on final cavities will be presented

RNA-binding and prion domains: the Yin and Yang of phase separation

Proteins and RNAs assemble in membrane-less organelles that organize intracellular spaces and regulate biochemical reactions. The ability of proteins and RNAs to form condensates is encoded in their sequences, yet it is unknown which domains drive the phase separation (PS) process and what are their specific roles. Here, we systematically investigated the human and yeast proteomes to find regions promoting condensation. Using advanced computational methods to predict the PS propensity of proteins, we designed a set of experiments to investigate the contributions of Prion-Like Domains (PrLDs) and RNA-binding domains (RBDs). We found that one PrLD is sufficient to drive PS, whereas multiple RBDs are needed to modulate the dynamics of the assemblies. In the case of stress granule protein Pub1 we show that the PrLD promotes sequestration of protein partners and the RBD confers liquid-like behaviour to the condensate. Our work sheds light on the fine interplay between RBDs and PrLD to regulate formation of membrane-less organelles, opening up the avenue for their manipulation