Principles of the Economic Analysis and Criteria for Evaluation of Corporate Structures Functioning

In this article, authors attempt to investigate and specify the principles of the economic analysis and criteria for evaluation of activity of corporate structures in the conditions of instability of the external environment that allowed defining degree of completeness of their realization in practice. For receiving quality and objective standard of the economic analysis results, in the course of its carrying out we seek to consider the established principles representing the set of rules. Based on the outcomes, it can be concluded that the possibility of their full realization in many respects depends on institutional, legal and infrastructure conditions, professionalism of management of that region in the territory of which the corporation is located. Need of introduction of the principles of adaptability, relevance, independence, clarity and openness of results of the economic analysis is proved

Oxidation technology as a decorative coating in the artistic treatment of metal

The task set for this paper is view the process of oxidation on high temperatures during the creation of products of art. The result of the author's analysis shows that said technique could be used in artistic purposes, showcasing the advantages and disadvantages of said method

EBSD analysis of the structural state of the Cu-Zn-Mn-Al-Fe-Ni alloy after hot deformation

The structural state of the Cu-Zn-Mn-Al-Fe-Ni alloy after high-temperature forming is studied. It is reported that in the section of a ring blank there are two structural zones with different amounts of strain. It has been found by EBSD analysis that in the maximum strain zone the alloy suffers dynamic recrystallization under forming, whereas in the minimum strain zone there is only dynamic polygonization, coarse grain boundaries become strengthened, this being ac-companied by an increase in the values of hardness to 300 HV 0.2; this causes their embrittlement and brittle grain-boundary cracking of the blank at room temperature under the effect of residual stresses. © 2017 Author(s).The study was partially supported by the UB RAS basic research program, project No. 15-10-1-22. The research was done with the use of the equipment of the Plastometriya collective use center affiliated to IES UB RAS

CTCF mediates chromatin looping via N-terminal domain-dependent cohesin retention

The DNA-binding protein CCCTC-binding factor (CTCF) and the cohesin complex function together to shape chromatin architecture in mammalian cells, but the molecular details of this process remain unclear. Here, we demonstrate that a 79-aa region within the CTCF N terminus is essential for cohesin positioning at CTCF binding sites and chromatin loop formation. However, the N terminus of CTCF fused to artificial zinc fingers was not sufficient to redirect cohesin to non-CTCF binding sites, indicating a lack of an autonomously functioning domain in CTCF responsible for cohesin positioning. BORIS (CTCFL), a germline-specific paralog of CTCF, was unable to anchor cohesin to CTCF DNA binding sites. Furthermore, CTCF-BORIS chimeric constructs provided evidence that, besides the N terminus of CTCF, the first two CTCF zinc fingers, and likely the 3D geometry of CTCF-DNA complexes, are also involved in cohesin retention. Based on this knowledge, we were able to convert BORIS into CTCF with respect to cohesin positioning, thus providing additional molecular details of the ability of CTCF to retain cohesin. Taken together, our data provide insight into the process by which DNA-bound CTCF constrains cohesin movement to shape spatiotemporal genome organization

The use of intermediate inserts for CO 2 laser welding of steel AISI 321 and a Grade 2 titanium alloy

The paper studies the structure, chemical and phase compositions, hardness and strength of welded joints obtained in AISI 321 steel and Grade 2 titanium alloy sheets by CO 2 continuous laser with the use of intermediate Cu, Ni and Ag-Cu-Zn alloy inserts. It is demonstrated that the maximum strength of welded joints is achieved by the welding conditions enabling one to form multiphase structures with intermetallics in the material of a weld, rather than only those based on solid solutions. © 2018 Author(s)

The main psychological determinants of the participants’ readiness of professional skill competitions to perform successfully

The article presents the results of psychological research and the primary analysis of the results obtained, which allow us to formulate the main psychological determinants of the readiness of the contestants for competitions in professional skills and possible success. The study was conducted by means of questionnaire methods, primary statistical processing (percentage ratio), comparative analysis of the data obtained. The object of the study was the participants of professional skill competitions: winners, prize-winners and contestants who performed unsuccessfully. It was revealed that the winners and prize-winners of professional skill competitions, as well as participants who performed unsuccessfully, actively use psychological and professional techniques, techniques, creativity, and so on in preparation for competitions. The personal and professional qualities of the contestants contributing to their success and possible reasons for unsuccessful performances are noted. The main psychological determinants of the contestants’ readiness for competitions in professional skills and possible success are identified and formulated – personality strength; confidence; a high level of need for achievements and victories; an adequate level of self-esteem; a high level of reflection; competent knowledge of psychological technologies of self-action; a high level of personal and professional qualities development; rational independence in preparation

Two New Metacercariae of Genus Austrodiplostomum (Trematoda: Diplostomidae) from Oreochromis niloticus (Cichlidae) and Varicorhinus beso (Cyprinidae) in Tana Lake, Ethiopia

Metacercariae of two new trematode species of the genus Austrodiplostomum are described from fishes of Tana Lake in Ethiopia: Austrodiplostomum sp. 1 from cranial cavity of Oreochromis niloticus and Austrodiplostomum sp. 2 from vitreous humor of Varicorhinus beso. New species metacercariae differs from A. mordax metacercariae in the shape of body, the size of body and organs, the shape of anterior extremity, and site of infection. This is the first record of Austrodiplostomum metacercariae from fish in Afric

The Porous Structure of Copper-cadmium Oxide System Prepared by AC Electrochemical Synthesis

The porous structure of nanoparticles of copper-cadmium oxide system prepared by AC electrochemical synthesis in sodium chloride with a concentration of 3, 15, 25 wt. % has been studied. The obtained data indicate that at a higher current density and sodium chloride concentration of 3% wt. in the electrochemical oxidation of cadmium and copper products are formed with the structure of mesopores and channels. In this case, the specific surface area has the greatest value (19.4 m{2}/g) and a maximum pore volume (0.0778 cm{3}/g). Thus, the obtained data allow predicting the operating parameters of the electrolysis to obtain a copper - cadmium oxide system of a predetermined porous structure

The WW-HECT protein Smurf2 interacts with the Docking Protein NEDD9/HEF1 for Aurora A activation

The multi-functional adaptor protein NEDD9/HEF1/Cas-L regulates cell motility, invasion and cell cycle progression, and plays key roles in cancer progression and metastasis. NEDD9 is localized to the centrosome and is required for activation of Aurora A kinase in mitosis. Here we demonstrate that the HECT-WW protein Smurf2 physically associates with NEDD9 and is required for the stability of NEDD9 protein. Smurf2 depletion results in a marked decrease in NEDD9 protein levels, by facilitating polyubiquitination and proteasomal degradation of NEDD9. Conversely, forced overexpression of Smurf2 results in upregulation of endogenous NEDD9 protein, confirming the role for Smurf2 in NEDD9 stability. Cells with Smurf2 depletion fail to activate Aurora A at the G2/M boundary, leading to a marked delay in mitotic entry. These observations suggest that the stable complex of Smurf2 and NEDD9 is required for timely entry into mitosis via Aurora A activation