Biodiesel: Freedom from Dependence on Fossil Fuels?

In view of the depleting oil reserves and exponential rise in petroleum prices, the search for alternative sources of fuel is very timely and important. The present paper addresses the underlying issues in biodiesel production from biomaterials and sustainable production and supply of first-generation biofuels, especially the one from jatropha. The agencies and research institutions involved in the production of biofuels and the national and international efforts made in this regard are discussed here. There is also a dire need of a step towards large-scale production and supply of second-generation biofuels, although in infant stage, to strengthen the world economy in general and Indian economy in particular. However, the production of biofuels are likely to have serious socio-economic implications especially to the lesser developed societies. This needs serious attention from policy makers and public at large

Ethnomedicinal Observations among Forest Dwellers of the Daitari Range of Hills of Orissa, India

Studies on hill tribes’ dependence on forest for their livelihood security are few for Orissa. Ethno medicinal observations in the state with a rich diversity of medicinal plants are still meager. The present study enumerates 21 plant species belonging to 18 families used in the treatment of various diseases among the tribes of Daitari Hill ranges of Orissa. The forest dwellers usually collect those rare plants from the nearby forest which is easily accessible and the medicines are prepared under the guidance of Vaidya or the village medicine man and are applied according to the dosage prescribed by the Vaidya. So this article gives an idea about the application of traditional medicines against various common and serious diseases

Covishield vaccine experience in a health care setting

Background: SARS-CoV-2 pandemic has affected the whole world and India is one among the most affected countries. Vaccination is the most important tool to halt this pandemic and vaccine hesitancy unfortunately derails vaccination drive. Vaccine hesitancy among people is mainly due to concerns about vaccine safety! This study was done to assess adverse effects of Covishield vaccine among health care workers in a single health care organization.Methods: All the vaccine recipients were requested to answer a questionnaire with demographic details and various side effects following both the doses of Covishield vaccination.Results: About 665 employees responded to the questionnaire and the most common adverse reaction following Covishield vaccine was injection site pain, which was reported by 63% of vaccinees after first dose of vaccine.Conclusions: Covishield vaccine is relatively safe and incidence of major adverse events are rare following vaccination

The influence of consolidation force on the performance of AFP manufactured laminates

With the increasing use of carbon/glass fibre reinforced polymer composites for large components like wing skins, fuselages and fuel tanks in aircrafts and next generation of spacecraft, utilization of advanced automated manufacturing is critical for mass production. In-situ consolidation in automated fibre placement (AFP) technology through merging several manufacturing stages like cutting, curing and consolidation has opened up a wider range of applications as well as new markets for composite materials in several sectors including aerospace and automobile in large scale. Nevertheless, the quality and integrity of AFP manufactured composites is heavily dependent on large number of variables and parameters like lay-up speed, curing/melting temperature and consolidation force. In order to establish and understand a correlation between the key parameters in AFP and the mechanical properties, several parametric experiments were performed. This is done through manufacturing uni-directional carbon fibre reinforced polymer laminates and identifying some of their main mechanical properties at different location along the length of samples. It was found that, the strength of laminates at different locations is critically dependent on the effect of those parameters

Fabrication and characterization of a magnetized metal-encapsulated FBG sensor for structural health monitoring

A novel means of metal packaging of a fiber Bragg grating (FBG) sensor using stainless steel and tin, together with high temperature resistant samarium cobalt (SmCo) magnet is proposed in this paper. The inclusion of high temperaturecapable SmCo magnets enable the metal packaging of the FBG sensor with magnetic capabilities. This packaged sensor can be placed in direct contact with the substrate structures such as iron pipelines and other ferromagnetic components without any adhesives, making them easily detachable and reusable. This is a significant improvement compared with other commercial fiber optic sensors which are, surface attached using epoxies or welded to the substrate. The design parameters and characteristic properties such as load, temperature, and vibration sensitivity of the magnetic metal-packaged FBG sensor are studied numerically and validated experimentally to demonstrate the feasibility of using the encapsulated reusable FBGs for structural health monitoring of compatible structures

Le micocoulier : de l'arbre au fouet

Cet article expose le procédé (peu connu) de fabrication des cravaches et fouets d'attelage à partir de micocoulier du Roussillon, patrimoine mis en valeur de façon traditionnell

Ultrathin Plasmonic Tungsten Oxide Quantum Wells with Controllable Free Carrier Densities

Localized surface plasmon resonances (LSPR) of nanostructures can be tuned by controlling their morphology, local dielectric environment, and free carrier concentration. We report the colloidal synthesis of an ∼3 tungsten–oxygen (W-O) layer thick (∼1 nm), two-dimensional (2D) WO3-x nanoplatelets (NPLs) (x ≈ 0.55–1.03), which display tunable near-infrared LSPR properties and additionally high free electron density (Ne) that arises predominantly from the large shape factor of 2D NPLs. Importantly, the W to O composition ratios inferred from their LSPR measurements show much higher percentage of oxygen vacancies than those determined by X-ray diffraction analysis, suggesting that the aspect ratio of ultrathin WO3-x NPLs is the key to producing an unprecedentedly large Ne, although synthesis temperature is also an independent factor. We find that NPL formation is kinetically controlled, whereas thermodynamic parameter manipulation leads to Ne values as high as 4.13 × 1022 cm–3, which is close to that of plasmonic noble metals, and thus our oxide-based nanostructures can be considered as quasi-metallic. The unique structural properties of 2D nanomaterials along with the high Ne of WO3-x NPLs provide an attractive alternative to plasmonic noble metal nanostructures for various plasmon-driven energy conversions and design of photochromic nanodevices

Dissecting HSV-1-induced host shut-off at RNA level

Herpes simplex virus 1 (HSV-1) installs a profound host shut-off during lytic infection. The virion host shut-off (vhs) protein plays a key role in this process by efficiently cleaving both host and viral mRNAs in a translation-initiation-dependent manner. Furthermore, the onset of viral DNA replication is accompanied by a rapid decline in transcriptional activity of the host genome. Both mechanisms have tremendous impact on the RNA expression profile of the infected cells. To dissect their relative contributions and elucidate gene-specific host transcriptional responses throughout the first 8h of lytic HSV-1 infection, we here employed RNA-seq of total, newly transcribed (4sU-labelled) and chromatin-associated RNA in wild-type (WT) and Δvhs infection of primary human fibroblasts. Following virus entry, vhs activity rapidly plateaued at an elimination rate of around 30% of cellular mRNAs per hour until 8h p.i. In parallel, host transcriptional activity dropped down to 10-20%. While the combined effects of both phenomena dominated infection-induced changes in total RNA, extensive gene-specific transcriptional regulation was observable in chromatin-associated RNA. This was surprisingly concordant between WT HSV-1 and its Δvhs mutant and at least in parts mediated by the embryonic transcription factor DUX4. Furthermore, both WT and Δvhs infection induced strong transcriptional up-regulation of a small subset of genes. Most of these were either poorly or not at all expressed prior to infection but already primed by H3K4me3 histone marks at their promoters. Most interestingly, analysis of chromatin-associated RNA revealed vhs-nuclease-activity-dependent transcriptional down-regulation of at least 150 cellular genes, in particular of many genes encoding integrin adhesome and extracellular matrix components. This was accompanied by a vhs-dependent reduction in protein levels by 8h p.i. for many of these genes. In summary, our study provides a comprehensive picture of the molecular mechanisms that govern cellular RNA metabolism during the first 8h of lytic HSV-1 infection