Hydrogeological study of the monti sibillini north-western sector: a contribution to the official hydrogeologic mapping

This work underlines the importance of experimental data and integrates the hydrogeological mapping methods. The work has analyzed the lithological features of the outcropping rocks and their attitude to be crossed by the meteoric waters. Geologic-structural analysis has allowed to identify elements that can constitute the hydraulic barriers and the hydrogeological complexes that can contain the aquifers. A detailed analysis of base flow was carried out through hydrogeological survey directly performed in the river. The hydrogeological survey has allowed us: 1) to appraise the river's base flow; 2) to identify the punctual and linear springs; 3) to quantify the water resource on average drained; and 4) to determine the discharge regime of springs and rivers. The Conceptual Hydrogeological Model for each individual aquifer have been derived from geologic-structural analysis and hydrogeological studies. The Conceptual Hydrogeological Models allowed us to calculate the Mean Effective Infiltration (Ieff) of every aquifer. The values of Ieff are gathered in classes. All merged information has been used in the preparation of Hydrogeological Complexes and Natural Springs Map. The manifold hydrogeological information cannot be represented in one document only; so the Experimental Hydrogeological Mapping has been prepared as the overlap of different informative levels: Hydrogeological Complexes and Natural Springs Map (principal document), Surface Hydrology Map and Conceptual Hydrogeological Models of several recognized aquifers (complementary elements)

A proposal for compiling quantitative hydrogeological maps

An innovative approach to hydrogeological mapping based on quantitative analysis is shown in this paper. It gives some cartographical solutions for an immediate evaluation of the groundwater resources and their spatial distribution. All relevant aquifers, springs and their regime, geological and structural setting and their hydraulic role should be shown in several understandable and clear hydrogeological maps where all hydrogeological information is reported in detail in the “Hydrogeological experimental Map” composed by a. “Hydrogeological Complexes and Natural Springs Map”, b. “Surface Hydrology Map”, c. “Conceptual Hydrogeological Model” and d. “Hydrogeological sections”. The cartographical solutions adopted for representing all these documents are proposed in this paper. Some graphical solutions have been proposed for improving the Italian official guidelines of hydrogeological mapping at scale 1:50.000, explain the legends symbols and illustrate the structure of a hydrogeological GIS database. An application of this approach has been carried out in north-western sector of Sibillini Mts. (Marche, Italy)

Surface evidence of active tectonics along the Pergola-Melandro fault: a critical

The Pergola-Melandro basin (southern Apennines) is characterized by a below-average release of seismic energy within a wider earthquake-prone region. In fact, it is placed between the maximum intensity areas of two of the most destructive earthquakes reported in the Italian seismic catalogue: the M ≥ 7.0 Agri Valley earthquake in 1857 and the Ma = 6.9 Irpinia earthquake in 1980. In this work, we present geomorphologic analysis, electrical resistivity surveys and field data, including paleoseismologic evidence, that provided the first direct constraints on the presence of a ~20 km long, seismogenic fault at the western border of the Pergola-Melandro basin. We also obtained geological information on the recent deformation history of the Pergola-Melandro fault that indicates the occurrence of at least four surface faulting earthquakes since Late Pleistocene age. The empirical relationships linking fault length and magnitude would assign to the Pergola- Melandro fault an event of M ≥ 6.5. These new data have important implication on the seismic hazard assessment of this sector of the Apennines, that also includes large cities such as Potenza, about 20 km far from the recognized Pergola-Melandro fault, and highlight the relevance of the geological approach in areas where the seismological records are poor. Finally, we discuss the Pergola-Melandro fault within the regional seismotectonic context. In particular, this fault belongs to the system of normal faults with an apenninic orientation, both NE and SW dipping, that accommodate the NE- crustal extension taking place in the area. Nearby faults, similarly oriented but with opposite dip, may coexist whether linked by secondary faults that act as slip transfer structures. This complex system of active faults would be more realistic than to consider a narrow band of faults, running along the belt axis, with an homogenous geometry and, moreover, more consistent with the high extension rate measured by historical earthquakes and geodetic data

Multi-criteria approach for the environmental impact assessment of inland aquaculture

Trout farming, that represents the most important sector for aquaculture inland production in Italy, can cause negative effects on aquatic ecosystems. Recently, in the framework of Water Frame Directive 2000/60/EC and national law DL 152/2006, concerning the sustainable uses of water resources, multi-criteria approaches have been suggested to evaluate the impact of fish farming on aquatic ecosystems. In this study trout farms of central Italy were selected to investigate the effects of their effluents, on receiving water bodies using a multi-criteria approach based on physicochemical parameters, microbiological and macrobenthonic indicators, detected in sampling stations located upstream/downstream the trout farm. Moreover, antibiotic susceptibility against antibiotics allowed and/or forbidden by current law (D.lgs 193/56/06) was tested on E. coli strains. The results indicate variations of chemical parameters and biological indicators from upstream to downstream sites in some of the investigated farms. Antibiotic resistance of E. coli strains suggested a large use of tetracycline and a possible past use of chloramphenicol. This study represents a first contribute to the knowledge of fish farm impacts on aquatic systems in Central Italy

Pattern of seismicity in the Lucanian Apennines and foredeep (Southern Italy) from recording by SAPTEX temporary array

The deployment of a temporary seismic network in Southern Italy during 2001-2004 (the SAPTEX array, Southern APennine Tomography EXperiment) allowed us to relocate the hypocenters of Southern Apennines earthquakes with low uncertainty among the location parameters. The best array distribution of the SAPTEX network for the analysis of seismicity in the Lucanian Apennines and foredeep was reached in the first two years of recording. The SAPTEX data were merged with those of the Italian National Seismic Network (RSNC) operated by the Istituto Nazionale di Geofisica e Vulcanologia (INGV). For the hypocenters computation of events in the upper Agri Valley we also included P- and S- waves arrivals from the local Eni-Agip network. The seismicity for the Lucanian Apennines and foredeep in the analyzed period has magnitudes ranging from 2.0 to 4.1. A major finding is the identification of two different crustal domains: the westernmost characterizing the chain, mostly with shallow earthquakes (within about 20 km of depth), and the easternmost one belonging to the outer margin of the chain and to the foredeep, with deeper seismicity (mostly between 20-40 km of depth). Thirty fault-plane solutions were computed and used for stress inversion; most of them are related to earthquakes within the chain sector and indicate a generalized NE-SW extension. Moreover, the dense network allowed us to improve the location of events relative to two low magnitude sequences which occurred in the study period

Surface evidence of active tectonics along the Pergola-Melandro

The Pergola-Melandro basin (southern Apennines) is characterized by a below-average release of seismic energy within a wider earthquake-prone region. In fact, it is placed between the maximum intensity areas of two of the most destructive earthquakes reported in the Italian seismic catalogue: theM≥7.0 Agri Valley earthquake in 1857 and the Ms = 6.9 Irpinia earthquake in 1980. In thiswork, we present geomorphologic analysis, electrical resistivity surveys and field data, including paleoseismologic evidence, that provided the first direct constraints on the presence of a∼20 kmlong, seismogenic fault at the western border of the Pergola-Melandro basin. We also obtained geological information on the recent deformation history of the Pergola-Melandro fault that indicates the occurrence of at least four surface faulting earthquakes since Late Pleistocene age. The empirical relationships linking fault length and magnitude would assign to the Pergola-Melandro fault an event of M≥6.5. These new data have important implication on the seismic hazard assessment of this sector of the Apennines, that also includes large cities such as Potenza, about 20 km far from the recognized Pergola-Melandro fault, and highlight the relevance of the geological approach in areas where the seismological records are poor. Finally, we discuss the Pergola-Melandro fault within the regional seismotectonic context. In particular, this fault belongs to the system of normal faults with an apenninic orientation, both NE and SW dipping, accommodating the NE-crustal extension taking place in the area. Nearby faults, similarly oriented but with opposite dip, may coexist whether linked by secondary faults that act as slip transfer structures. This complex system of active faults would be more realistic than a narrow band of faults running along the belt axis with an homogenous geometry, and moreover, it is more consistent with the high extension rate measured by historical earthquakes and geodetic data

The Vallo di Diano Range-Bounding Fault-System (Southern Italy): New Evidence of Recent Activity From High-Resolution Seismic Profiling

The Vallo di Diano is the largest intermountain basin in the Southern Apennines (Italy). The basin evolution was controlled by the Quaternary activity of a range-bounding, SW-dipping normal fault system located to the east (Vallo di Diano Fault System, VDFS). Geological and oil industry data define the sin-sedimentary activity of the VDFS up to the Middle Pleistocene. However, commercial profiles do not resolve the shallower, eastern portion of the basin, due to strong lateral heterogeneities and unfavourable surface conditions. Therefore, Late Pleistocene-Holocene activity of the VDFS and its seismogenic potential are still uncertain. To better constrain the shallow structure of the basin, we performed four high-resolution seismic surveys, along its eastern side, where slope breccias and fans cover the Mesozoic carbonate bedrock and bury the VDFS. We also investigated some NW-trending flexures affecting Late Pleistocene fans, that we had previously detected and dubitatively ascribed to recent faulting. Seismic data were acquired with a dense wide-aperture geometry. Two high-resolution (HR) NE-trending profiles, about 1.5 km long, were collected using respectively 5 m and 10 m spaced receivers and sources. Two very high-resolution (VHR) NE-trending profiles, 400 and 350 m long, with densely spaced sources (4 m) and receivers (2 m) were also collected. HR profiling was aimed at imaging alluvial fan thickness and morphology of the underlying carbonate bedrock. VHR surveys targeted the flexures and their possible origin. All lines were acquired with a HR vibroseis source, except for the shortest profile, where we used a buffalo-gun, better suited for very near-surface imaging (z < 50 m depth). Seismic imaging consists of reflectivity images obtained by CDP-processing of reflection data complemented by Vp images obtained by multi-scale seismic tomography. The stack sections illuminated the basin down to 0.4-0.5 s TWT and reveal an array of high-angle, generally SW-dipping faults dissecting the bedrock and the alluvial fans. Faulting created accommodation space in the hanging-wall and displaced the different fan generations. Clear reflection truncations in the stack-sections correspond to significant Vp lateral changes in the tomographic images. VHR tomography is well defined along the shortest line down to 40 m depth, where two steps within slope breccias are visible. Moreover, two low-velocity wedges (colluvial packages) are imaged in the near surface (5-20 m depth). These data support recent faulting consistently with surface geomorphic features. We interpret these fault structures as splays of the range bounding master fault. Comparison with commercial reflection profiles nearby reveals a great improvement in seismic imaging achieved by HR surveys, which allow a detailed seismostratigraphic analysis of the basin.UnpublishedSan Francisco (CA), Moscone West, Howard Street3.2. Tettonica attivaope

CD4 T lymphocyte autophagy is upregulated in the salivary glands of primary Sjögren’s syndrome patients and correlates with focus score and disease activity

Background: Primary Sjögren’s syndrome (pSS) is a common chronic autoimmune disease characterized by lymphocytic infiltration of exocrine glands and peripheral lymphocyte perturbation. In the current study, we aimed to investigate the possible pathogenic implication of autophagy in T lymphocytes in patients with pSS. Methods: Thirty consecutive pSS patients were recruited together with 20 patients affected by sicca syndrome a nd/or chronic sialoadenitis and 30 healthy controls. Disease activity and damage were evaluated according to SS disease activity index, EULAR SS disease activity index, and SS disease damage index. T lymphocytes were analyzed for the expression of autophagy-specific markers by biochemical, molecular, and histological assays in peripheral blood and labial gland biopsies. Serum interleukin (IL)-23 and IL-21 levels were quantified by enzyme-linked immunosorbent assay. Results: Our study provides evidence for the first time that autophagy is upregulated in CD4+ T lymphocyte salivary glands from pSS patients. Furthermore, a statistically significant correlation was detected between lymphocyte autophagy levels, disease activity, and damage indexes. We also found a positive correlation between autophagy enhancement and the increased salivary gland expression of IL-21 and IL-23, providing a further link between innate and adaptive immune responses in pSS. Conclusions: These findings suggest that CD4+ T lymphocyte autophagy could play a key role in pSS pathogenesis. Additionally, our data highlight the potential exploitation of T cell autophagy as a biomarker of disease activity and provide new ground to verify the therapeutic implications of autophagy as an innovative drug target in pSS

Prevalence and Correlates of Sexually Transmitted Infections in Transgender People: An Italian Multicentric Cross-Sectional Study

The burden of sexually transmitted infections (STIs) in the transgender population remains an underestimated issue. The aims of the present study were to evaluate the prevalence of either self-reported and serological STIs and to describe socio-demographic and clinical characteristics of transgender individuals with STIs. A consecutive series of 705 transgender individuals (assigned-male at birth, AMAB n = 377; assigned-female at birth, AFAB n = 328) referring to six Italian gender clinics were included. Sociodemographic and clinical information was collected during the first visit. In a subsample of 126 individuals prevalence of STIs (human immunodeficiency virus, HIV; hepatitis C, HCV; hepatitis B, HBV; syphilis) were evaluated through serology tests. The self-reported prevalence of HIV, HBV, HCV and syphilis infection in the total sample were 3.4%, 1.6%, 2.6% and 2.0%, respectively. In the subsample who underwent serological tests, higher rates of serological prevalence were found (9.5%, 4.0%, 5.6% and 7.9% for HIV, HBV, HCV and syphilis, respectively). When comparing transgender people with or without selfreported STIs, unemployment, previous incarceration, justice problems and sex work resulted more frequent in the first group (p&lt; 0.03 for all). Regarding health status, we observed higher rates of lifetime substance abuse and psychiatric morbidities in trans people with at least one reported STI (p &lt; 0.05). The prevalence of STIs exceeded that reported in general population and STIs correlates underline the importance of stigma and discrimination as determinants of transgender health

The Vallo di Diano Range-Bounding Fault-System (Southern Italy): New Evidence of Recent Activity From High-Resolution Seismic Profiling

The Vallo di Diano is the largest intermountain basin in the Southern Apennines (Italy). The basin evolution was controlled by the Quaternary activity of a range-bounding, SW-dipping normal fault system located to the east (Vallo di Diano Fault System, VDFS). Geological and oil industry data define the sin-sedimentary activity of the VDFS up to the Middle Pleistocene. However, commercial profiles do not resolve the shallower, eastern portion of the basin, due to strong lateral heterogeneities and unfavourable surface conditions. Therefore, Late Pleistocene-Holocene activity of the VDFS and its seismogenic potential are still uncertain. To better constrain the shallow structure of the basin, we performed four high-resolution seismic surveys, along its eastern side, where slope breccias and fans cover the Mesozoic carbonate bedrock and bury the VDFS. We also investigated some NW-trending flexures affecting Late Pleistocene fans, that we had previously detected and dubitatively ascribed to recent faulting. Seismic data were acquired with a dense wide-aperture geometry. Two high-resolution (HR) NE-trending profiles, about 1.5 km long, were collected using respectively 5 m and 10 m spaced receivers and sources. Two very high-resolution (VHR) NE-trending profiles, 400 and 350 m long, with densely spaced sources (4 m) and receivers (2 m) were also collected. HR profiling was aimed at imaging alluvial fan thickness and morphology of the underlying carbonate bedrock. VHR surveys targeted the flexures and their possible origin. All lines were acquired with a HR vibroseis source, except for the shortest profile, where we used a buffalo-gun, better suited for very near-surface imaging (z < 50 m depth). Seismic imaging consists of reflectivity images obtained by CDP-processing of reflection data complemented by Vp images obtained by multi-scale seismic tomography. The stack sections illuminated the basin down to 0.4-0.5 s TWT and reveal an array of high-angle, generally SW-dipping faults dissecting the bedrock and the alluvial fans. Faulting created accommodation space in the hanging-wall and displaced the different fan generations. Clear reflection truncations in the stack-sections correspond to significant Vp lateral changes in the tomographic images. VHR tomography is well defined along the shortest line down to 40 m depth, where two steps within slope breccias are visible. Moreover, two low-velocity wedges (colluvial packages) are imaged in the near surface (5-20 m depth). These data support recent faulting consistently with surface geomorphic features. We interpret these fault structures as splays of the range bounding master fault. Comparison with commercial reflection profiles nearby reveals a great improvement in seismic imaging achieved by HR surveys, which allow a detailed seismostratigraphic analysis of the basin