30,122 research outputs found
Hamiltonian Reduction of -theories at the Level of Correlators
Since the work of Bershadsky and Ooguri and Feigin and Frenkel it is well
known that correlators of current algebra for admissible
representations should reduce to correlators for conformal minimal models. A
precise proposal for this relation has been given at the level of correlators:
When primary fields are expressed as with being
a variable to keep track of the representation multiplet (possibly
infinitely dimensional for admissible representations), then the minimal model
correlator is supposed to be obtained simply by putting all . Although
strong support for this has been presented, to the best of our understanding a
direct, simple proof seems to be missing so in this paper we present one based
on the free field Wakimoto construction and our previous study of that in the
present context. We further verify that the explicit correlators we
have published in a recent preprint reduce in the above way, up to a constant
which we also calculate. We further discuss the relation to more standard
formulations of hamiltonian reduction.Comment: 13 pages, LaTe
Fast fluorescence dynamics in non-ratiometric calcium indicators
A fluorescence decay of high-affinity non-ratiometric Ca2+ indicator Oregon
Green BAPTA-1 (OGB-1) is analyzed with unprecedented temporal resolution in the
two-photon excitation regime. A triple exponential decay is shown to best fit
the fluorescence dynamics of OGB-1. We provide a new model for accurate
measurements of the free Ca2+ concentration and dissociation constants of
non-ratiometric calcium indicators.Comment: 3 pages, 2 figures, figures revised, added chi-square goodness of fi
Anomalous Chiral Action from the Path-Integral
By generalizing the Fujikawa approach, we show in the path-integral
formalism: (1) how the infinitesimal variation of the fermion measure can be
integrated to obtain the full anomalous chiral action; (2) how the action
derived in this way can be identified as the Chern-Simons term in five
dimensions, if the anomaly is consistent; (3) how the regularization can be
carried out, so as to lead to the consistent anomaly and not to the covariant
anomaly. Our method uses Schwinger's ``proper-time'' representation of the
Green's function and the gauge invariant point-splitting technique. We find
that the consistency requirement and the point-splitting technique allow both
an anomalous and a non-anomalous action. In the end, the nature of the vacuum
determines whether we have an anomalous theory, or, a non-anomalous theoryComment: 28 page
Robust observer for uncertain linear quantum systems
In the theory of quantum dynamical filtering, one of the biggest issues is
that the underlying system dynamics represented by a quantum stochastic
differential equation must be known exactly in order that the corresponding
filter provides an optimal performance; however, this assumption is generally
unrealistic. Therefore, in this paper, we consider a class of linear quantum
systems subjected to time-varying norm-bounded parametric uncertainties and
then propose a robust observer such that the variance of the estimation error
is guaranteed to be within a certain bound. Although in the linear case much of
classical control theory can be applied to quantum systems, the quantum robust
observer obtained in this paper does not have a classical analogue due to the
system's specific structure with respect to the uncertainties. Moreover, by
considering a typical quantum control problem, we show that the proposed robust
observer is fairly robust against a parametric uncertainty of the system even
when the other estimators--the optimal Kalman filter and risk-sensitive
observer--fail in the estimation.Comment: 11 pages, 1 figur
Microminiaturized, biopotential conditioning system (MBCS)
Multichannel, medical monitoring system allows almost complete freedom of movement for subject during monitoring periods. System comprises monitoring unit (biobelt), transmission line, and data acquisition unit. Belt, made of polybenzimidizole fabric, is wrapped around individual's waist and held in place by overlapping sections of Velcro closure material
Gains from the upgrade of the cold neutron triple-axis spectrometer FLEXX at the BER-II reactor
The upgrade of the cold neutron triple-axis spectrometer FLEXX is described.
We discuss the characterisation of the gains from the new primary spectrometer,
including a larger guide and double focussing monochromator, and present
measurements of the energy and momentum resolution and of the neutron flux of
the instrument. We found an order of magnitude gain in intensity (at the cost
of coarser momentum resolution), and that the incoherent elastic energy widths
are measurably narrower than before the upgrade. The much improved count rate
should allow the use of smaller single crystals samples and thus enable the
upgraded FLEXX spectrometer to continue making leading edge measurements.Comment: 8 pages, 7 figures, 5 table
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Safe use of symbols in handover documentation for medical teams
Concern has been reported about the safe use of medical abbreviations in documents such as handover sheets and medical notes, especially when information is being communicated between staff of different specialties (BBC 2008, Sheppard et al. 2008). This article describes a study to investigate whether the use of symbols in handover documentation that is shared within and between multidisciplinary teams (MDTs) has similar safety implications. We asked 19 healthcare professionals from a range of specialties to identify 45 different combinations of 38 individual symbols. The symbols and combinations of symbols were extracted from 102 handover sheets taken from 6 different healthcare contexts in 4 London hospitals. Three symbols proposed in Microsoft's Common User Interface guidelines for alert symbols were also included. Results reveal that while some symbols are well understood, many others are either ambiguous or unknown. These results have implications for the safe use of symbols in medical documents, including paper and electronic handover documents and Electronic Patient Records (EPRs), especially where teams comprise individuals from different professional backgrounds, i.e. MDTs. We offer initial suggestions for standardisation and further research
The interaction âSupplyâ, âDemandâ, and âTechnological Capabilitiesâ in terms of Medical Subject Headings: A triple helix model of medical innovations
We develop a model of innovation that enables us to trace the interplay among three key dimensions of the innovation process: (i) demand of and (ii) supply for innovation, and (iii) technological capabilities available to generate innovation in the forms of products, processes, and services. Building on Triple Helix research, we use entropy statistics to elaborate an indicator of mutual information among these dimensions that can provide indication of reduction of uncertainty. To do so, we focus on the medical context, where uncertainty poses significant challenges to the governance of innovation. The Medical Subject Headings (MeSH) of MEDLINE/PubMed provide us with publication records classified within the categories âDiseasesâ (C), âDrugs and Chemicalsâ (D), âAnalytic, Diagnostic, and Therapeutic Techniques and Equipmentâ (E) as knowledge representations of demand, supply, and technological capabilities, respectively. Three case-studies of medical research areas are used as representative âentry perspectivesâ of the medical innovation process. These are: (i) Human Papilloma Virus, (ii) RNA interference, and (iii) Magnetic Resonance Imaging. We find statistically significant periods of synergy among demand, supply, and technological capabilities (C-D-E) that points to three-dimensional interactions as a fundamental perspective for the understanding and governance of the uncertainty associated with medical innovation. Among the pairwise configurations in these contexts, the demand-technological capabilities (C-E) provided the strongest link, followed by the supply-demand (D-C) and the supply-technological capabilities (D-E) channels
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