78 research outputs found

    The IntAct database:Efficient access to fine-grained molecular interaction data

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    The IntAct molecular interaction database (https://www.ebi.ac.uk/intact) is a curated resource of molecular interactions, derived from the scientific literature and from direct data depositions. As of August 2021, IntAct provides more than one million binary interactions, curated by twelve global partners of the International Molecular Exchange consortium, for which the IntAct database provides a shared curation and dissemination platform. The IMEx curation policy has always emphasised a fine-grained data and curation model, aiming to capture the relevant experimental detail essential for the interpretation of the provided molecular interaction data. Here, we present recent curation focus and progress, as well as a completely redeveloped website which presents IntAct data in a much more user-friendly and detailed way

    Traitement de la prononciation en langue étrangÚre : approches didactiques, méthodes automatiques et enjeux pour l'apprentissage

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    International audienceCet article, consacrĂ© au lien entre traitement automatique et apprentissage de la prononciation en L2, vise Ă  offrir une vue d’ensemble des mĂ©thodes et pratiques actuellement en cours dans les deux domaines de rĂ©fĂ©rence du sujet (la didactique des langues Ă©trangĂšres et le traitement automatique de la parole), en nous concentrant sur la dĂ©marche de correction phonĂ©tique, du diagnostic d’erreurs aux procĂ©dures de remĂ©diation. L’un des composants les plus novateurs de notre rĂ©flexion porte sur les apports de la phonologie de corpus, notamment des corpus oraux d’apprenants de L2. Cette rĂ©flexion nous conduit Ă  plaider en faveur d’une approche interdisciplinaire plus riche entre didacticiens et ingĂ©nieurs de la parole afin d’encourager le dĂ©veloppement des systĂšmes de correction automatique dans les curricula de L2

    Di-m-propionato-bis[dicarbonyl(triphenylphosphine)ruthenium(I)](Ru-Ru)

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    Visible-Light-Mediated Hydroxycarbonylation of Diazonium Salts

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    International audienceA visible light‐promoted catalytic photoredox hydroxycarbonylation was achieved on aryl diazonium salts whether preformed or generated in situ from the corresponding anilines. This strategy allows a straightforward access to a variety of carboxylic acids under mild conditions

    Photocatalyzed Synthesis of 3-Substituted Phthalides: A Key Access to (+/-)-Herbaric Acid

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    International audienceAn efficient organophotocatalyzed protocol was developed for the preparation of 3-substituted phthalides. The presented transformation was performed under particularly mild conditions within 6 h and was ultimately applied to a precursor of the herbaric acid
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