Entangling macroscopic diamonds at room temperature: Bounds on the continuous-spontaneous-localization parameters

A recent experiment [K. C. Lee et al., Science 334, 1253 (2011)] succeeded in detecting entanglement between two macroscopic specks of diamonds, separated by a macroscopic distance, at room temperature. This impressive results is a further confirmation of the validity of quantum theory in (at least parts of) the mesoscopic and macroscopic domain, and poses a challenge to collapse models, which predict a violation of the quantum superposition principle, which is the bigger the larger the system. We analyze the experiment in the light of such models. We will show that the bounds placed by experimental data are weaker than those coming from matter-wave interferometry and non-interferometric tests of collapse models.Comment: 7 pages, 3 figures, v2: close to the published version, LaTe

Impact of theoretical priors in cosmological analyses: the case of single field quintessence

Article / Letter to editorLeids Instituut Onderzoek Natuurkund

Cosmological data favor Galileon ghost condensate over Λ CDM

We place observational constraints on the Galileon ghost condensate model, a dark energy proposal in cubic-order Horndeski theories consistent with the gravitational-wave event GW170817. The model extends the covariant Galileon by taking an additional higher-order field derivative X2 into account. This allows for the dark energy equation of state wDE to access the region −2Theoretical Physic

Cosmological constraints and phenomenology of a beyond-Horndeski model

We study observational constraints on a specific dark energy model in the framework of Gleyzes-Langlois-Piazza-Vernizzi theories, which extends the Galileon ghost condensate (GGC) to the domain of beyond Horndeski theories. In this model, we show that the Planck cosmic microwave background (CMB) data, combined with datasets of baryon acoustic oscillations, supernovae type Ia, and redshift-space distortions, give the tight upper bound |α(0)H|≤O(10−6) on today’s beyond-Horndeski (BH) parameter αH. This is mostly attributed to the shift of CMB acoustic peaks induced by the early-time changes of cosmological background and perturbations arising from the dominance of αH in the dark energy density. In comparison to the Λ cold dark matter (ΛCDM) model, our BH model suppresses the large-scale integrated-Sachs-Wolfe tail of CMB temperature anisotropies due to the existence of cubic Galileons, and it modifies the small-scale CMB power spectrum because of the different background evolution. We find that the BH model considered fits the data better than ΛCDM according to the χ2 statistics, yet the deviance information criterion (DIC) slightly favors the latter. Given the fact that our BH model with αH=0 (i.e., the GGC model) is favored over ΛCDM even by the DIC, there are no particular signatures for the departure from Horndeski theories in current observations.Theoretical Physic

Impact of theoretical priors in cosmological analyses: the case of single field quintessence

Theoretical Physic

Upper estimate of martingale dimension for self-similar fractals

We study upper estimates of the martingale dimension $d_m$ of diffusion processes associated with strong local Dirichlet forms. By applying a general strategy to self-similar Dirichlet forms on self-similar fractals, we prove that $d_m=1$ for natural diffusions on post-critically finite self-similar sets and that $d_m$ is dominated by the spectral dimension for the Brownian motion on Sierpinski carpets.Comment: 49 pages, 7 figures; minor revision with adding a referenc

Strong lensing time delay constraints on dark energy: a forecast

Theoretical Physic

High efficacy of ozonated oils on the removal of biofilms produced by methicillin-resistant staphylococcus aureus (MRSA) from infected diabetic foot ulcers

© 2020 by the authors. Ozone has a high wound healing capacity and antibacterial properties and can be used as a complementary treatment in infections. Methicillin-resistant S. aureus (MRSA) is the most common pathogen found in infected diabetic foot ulcers. Most of MRSA are resistant to several classes of antibiotics and, therefore, there is a need for new, effective, and well-tolerated agents. Thus, we aimed evaluate the antimicrobial and antibiofilm potentials of ozonated vegetable oils against MRSA strains isolated from diabetic foot ulcers. Six ozonated oils were produced with concentrations of ozone ranging from 0.53 to 17 mg of ozone/g of oil. The peroxide values were determined for each oil. Ozonated oils content on fatty acid was determined by gas chromatography equipped with a flame ionization detector. The antimicrobial susceptibility testing was performed by the Kirby-Bauer disk diffusion method and the effect of ozonated oils on biofilm formation ability and on established biofilms was investigated. In general, the content in identified unsaturated fatty acid in oils decreased with the increase of ozonation time and, consequently, the peroxide value increased. Most bacterial strains were inhibited by ozonated oil at a concentration of 4.24 mg/g. Ozonated oils had moderate to high ability to remove adhered cells and showed a high capacity to eradicate 24 h old biofilms. Our results show promising use of ozonated oils on the treatment of infections, in particular those caused by multidrug-resistant MRSA strains.This work was funded by the R&D Project CAREBIO2—Comparative assessment of antimicrobial resistance in environmental biofilms through proteomics—towards innovative theranostic biomarkers, with reference NORTE-01-0145-FEDER-030101 and PTDC/SAU-INF/30101/2017, financed by the European Regional Development Fund (ERDF) through the Northern Regional Operational Program (NORTE 2020) and the Foundation for Science and Technology (FCT). This work was supported by the Associate Laboratory for Green Chemistry—LAQV, which is financed by national funds from FCT/MCTES (UIDB/50006/2020). Joana S. Amaral is grateful to the Foundation for Science and Technology (FCT, Portugal) for financial support by national funds FCT/MCTES to CIMO (UIDB/00690/2020). Vanessa Silva is grateful to FCT (Fundação para a Ciência e a Tecnologia) for financial support through PhD grant SFRH/BD/137947/2018.info:eu-repo/semantics/publishedVersio

High Efficacy of Ozonated Oils on the Removal of Biofilms Produced by Methicillin-Resistant Staphylococcus aureus (MRSA) from Infected Diabetic Foot Ulcers

[EN] Ozone has a high wound healing capacity and antibacterial properties and can be used as a complementary treatment in infections. Methicillin-resistant S. aureus (MRSA) is the most common pathogen found in infected diabetic foot ulcers. Most of MRSA are resistant to several classes of antibiotics and, therefore, there is a need for new, effective, and well-tolerated agents. Thus, we aimed evaluate the antimicrobial and antibiofilm potentials of ozonated vegetable oils against MRSA strains isolated from diabetic foot ulcers. Six ozonated oils were produced with concentrations of ozone ranging from 0.53 to 17 mg of ozone/g of oil. The peroxide values were determined for each oil. Ozonated oils content on fatty acid was determined by gas chromatography equipped with a flame ionization detector. The antimicrobial susceptibility testing was performed by the Kirby-Bauer disk diffusion method and the effect of ozonated oils on biofilm formation ability and on established biofilms was investigated. In general, the content in identified unsaturated fatty acid in oils decreased with the increase of ozonation time and, consequently, the peroxide value increased. Most bacterial strains were inhibited by ozonated oil at a concentration of 4.24 mg/g. Ozonated oils had moderate to high ability to remove adhered cells and showed a high capacity to eradicate 24 h old biofilms. Our results show promising use of ozonated oils on the treatment of infections, in particular those caused by multidrug-resistant MRSA strainsSIThis research was founded by the Ministerio de Ciencia, Innovación y Universidades (Spain, Project RTI2018-098267-R-C33) and the Junta de Castilla y León (Consejería de Educación, Spain, Project LE164G18