Optimized Off-Grid Energy Systems Using Climate-Based Energy Demand for Soft-Walled Facilities

Remote contingency military operations often require the use of temporary facilities powered by inefficient diesel generators that are expensive to operate and maintain. Site planners can reduce operating costs by augmenting generators with hybrid energy systems, but they must select the optimal design configuration based on the region’s climate to meet the power demand at the lowest cost. To assist planners, this paper proposes two innovative, climate-optimized, hybrid energy system selection models. The first model is capable of selecting the facility insulation type, solar array size, and battery backup system to minimize the annual operating cost. The Hybrid Energy Renewable Delivery System (HERDS) model builds on this model by minimizing the entire system’s net present cost, and accounts for the transportation costs of airlifting the system to an operational site. To demonstrate the first model’s capability in various climates, model performance was evaluated for applications in southwest Asia and the Caribbean. An additional case study was performed on Clark Air Base, Philippines to highlight the HERDS model’s capabilities. The capability of both models is expected to support planners of remote sites in their ongoing effort to minimize fuel requirements, lower annual operating costs and increase site resiliency

Insulation Sensitivity Analysis for an Optimized Fabric Shelter Off-grid Hybrid Energy System

During military and disaster relief operations, connecting to an established electrical grid is rarely an option. In these situations, camps consisting of poorly insulated fabric shelters are predominantly powered by inefficient diesel generators that require frequent fuel resupply. In order to reduce the fuel demand of these generators, camps may utilize photovoltaic-battery systems. This paper presents an innovative cost-performance model capable of optimizing solar array size, battery backup system, and shelter insulation type to minimize the operating cost of powering a single fabric shelter. Model performance was evaluated using one year of insolation, weather and energy requirement data from a shelter located in Southwest Asia. For a shelter with R-4.7 insulation, the model generated an optimal system configuration consisting of a 251 m2 solar array and an 86 kWh lithium-ion battery. Over one year, this system would reduce the fuel consumption by 97% and save $1.1 million, including system purchase price, compared to a diesel generator. The results of the case study analysis demonstrate the model’s unique capability to optimize photovoltaic-battery system size and shelter insulation material in order to minimize annual operating costs

Cost Analysis of Optimized Islanded Energy Systems in a Dispersed Air Base Conflict

The United States Air Force has implemented a dispersed air base strategy to enhance mission effectiveness for near-peer conflicts. Asset dispersal places many smaller bases across a wide geographic area, which increases resupply requirements and logistical complexity. Hybrid energy systems reduce resupply requirements through sustainable, off-grid energy production. This paper presents a novel hybrid energy renewable delivery system (HERDS) model capable of (1) selecting the optimal hybrid energy system design that meets demand at the lowest net present cost and (2) optimizing the delivery of the selected system using existing Air Force cargo aircraft. The novelty of the model’s capabilities is displayed using Clark Air Base, Philippines as a case study. The HERDS model selected an optimal configuration consisting of a 676-kW photovoltaic array, an 1846-kWh battery system, and a 200-kW generator. This hybrid energy system predicts a 54% reduction in cost and an 88% reduction in fuel usage, as compared to the baseline Air Force system. The HERDS model is expected to support planners in their ongoing efforts to construct cost-effective sites that minimize the transport and logistic requirements associated with remote installations. Additionally, the results of this paper may be appropriate for broader civilian applications

Meeting Temporary Facility Energy Demand with Climate-Optimized Off-Grid Energy Systems

Remote and contingency operations, including military and disaster-relief activities, often require the use of temporary facilities powered by inefficient diesel generators that are expensive to operate and maintain. Site planners can reduce operating costs by increasing shelter insulation and augmenting generators with photovoltaic-battery hybrid energy systems, but they must select the optimal design configuration based on the region’s climate to meet the power demand at the lowest cost. To assist planners, this paper proposes an innovative, climate-optimized, hybrid energy system selection model capable of selecting the facility insulation type, solar array size, and battery backup system to minimize the annual operating cost. To demonstrate the model’s capability in various climates, model performance was evaluated for applications in southwest Asia and the Caribbean. For a facility in Southwest Asia, the model reduced fuel consumption by 93% and saved $271 thousand compared to operating a diesel generator. The simulated facility in the Caribbean resulted in more significant savings, decreasing fuel consumption by 92$291 thousand. This capability is expected to support planners of remote sites in their ongoing effort to minimize fuel supply requirements and annual operating costs of temporary facilities

Jedi public health: Co-creating an identity-safe culture to promote health equity

© 2016 The Authors. The extent to which socially-assigned and culturally mediated social identity affects health depends on contingencies of social identity that vary across and within populations in day-to-day life. These contingencies are structurally rooted and health damaging inasmuch as they activate physiological stress responses. They also have adverse effects on cognition and emotion, undermining self-confidence and diminishing academic performance. This impact reduces opportunities for social mobility, while ensuring those who "beat the odds" pay a physical price for their positive efforts. Recent applications of social identity theory toward closing racial, ethnic, and gender academic achievement gaps through changing features of educational settings, rather than individual students, have proved fruitful. We sought to integrate this evidence with growing social epidemiological evidence that structurally-rooted biopsychosocial processes have population health effects. We explicate an emergent framework, Jedi Public Health (JPH). JPH focuses on changing features of settings in everyday life, rather than individuals, to promote population health equity, a high priority, yet, elusive national public health objective. We call for an expansion and, in some ways, a re-orienting of efforts to eliminate population health inequity. Policies and interventions to remove and replace discrediting cues in everyday settings hold promise for disrupting the repeated physiological stress process activation that fuels population health inequities with potentially wide application.National Institute on Aging (Grant # R01 AG032632)National Institute on Aging (Grant # T32 AG00221

Close genetic linkage between X linked retinitis pigmentosa and a restriction fragment length polymorphism identified by recombinant DNA probe L1.28

Retinitis pigmentosa (RP) is a group of retinal degeneration characterized by progressive visual field loss, night blindness and pigmentary retinopathy. Its prevalence is in the region of 1-2 in 5,000 of the general population, making it one of the commoner causes of blindness in early and middle life. Although 36-48% of RP patients are isolated cases, the remainder show autosomal dominant, autosomal recessive or X-linked modes of inheritance. The X-linked variety ( XLRP ) is found in 14-22% of RP families in the UK. In the present study, X chromosome-specific recombinant DNA probes which can detect restriction fragment length polymorphisms have been used to localize the XLRP gene(s) to a subregion of the X chromosome using linkage analysis. One of the probes, L1.28, has been shown to be closely linked to XLRP in five kindreds, with 95% confidence limits of 0-15 centimorgans (maximum LOD score of 7.89 at a distance of 3 centimorgans). This suggests that the XLRP locus lies on the proximal part of the short arm of the X chromosome. This probe is potentially useful for carrier detection and early diagnosis in about 40% of cases, provided that genetic heterogeneity can be excluded by analysis of further families

Predicting Partner HIV Testing and Counseling Following a Partner Notification Intervention

Provider-assisted methods of partner notification increase testing and counseling among sexual partners of patients diagnosed with HIV, however they are resource-intensive. The sexual partners of individuals enrolled in a clinical trial comparing different methods of HIV partner notification were analyzed to identify who was unlikely to seek testing on their own. Unconditional logistic regression was used to identify partnership characteristics, which were assigned a score based on their coefficient in the final model, and a risk score was calculated for each participant. The risk score included male partner sex, relationship duration 6–24 months, and index education > primary. A risk score of ≥ 2 had a sensitivity of 68% and specificity of 78% in identifying partners unlikely to seek testing on their own. A risk score to target partner notification can reduce the resources required to locate all partners in the community while increasing the testing yield compared to patient-referral

HIV Partner Notification Is Effective and Feasible in Sub-Saharan Africa: Opportunities for HIV Treatment and Prevention

Sexual partners of persons with newly diagnosed HIV infection require HIV counseling, testing and, if necessary, evaluation for therapy. However, many African countries do not have a standardized protocol for partner notification and the effectiveness of partner notification has not been evaluated in developing countries

Host Genetics and Environmental Factors Regulate Ecological Succession of the Mouse Colon Tissue-Associated Microbiota

Background: The integration of host genetics, environmental triggers and the microbiota is a recognised factor in the pathogenesis of barrier function diseases such as IBD. In order to determine how these factors interact to regulate the host immune response and ecological succession of the colon tissue-associated microbiota, we investigated the temporal interaction between the microbiota and the host following disruption of the colonic epithelial barrier. Methodology/Principal Findings: Oral administration of DSS was applied as a mechanistic model of environmental damage of the colon and the resulting inflammation characterized for various parameters over time in WT and Nod2 KO mice. Results: In WT mice, DSS damage exposed the host to the commensal flora and led to a migration of the tissue-associated bacteria from the epithelium to mucosal and submucosal layers correlating with changes in proinflammatory cytokine profiles and a progressive transition from acute to chronic inflammation of the colon. Tissue-associated bacteria levels peaked at day 21 post-DSS and declined thereafter, correlating with recruitment of innate immune cells and development of the adaptive immune response. Histological parameters, immune cell infiltration and cytokine biomarkers of inflammation were indistinguishable between Nod2 and WT littermates following DSS, however, Nod2 KO mice demonstrated significantly higher tissue-associated bacterial levels in the colon. DSS damage and Nod2 genotype independently regulated the community structure of the colon microbiota

Relationship between visual field loss and contrast threshold elevation in glaucoma

BACKGROUND: There is a considerable body of literature which indicates that contrast thresholds for the detection of sinusoidal grating patterns are abnormally high in glaucoma, though just how these elevations are related to the location of visual field loss remains unknown. Our aim, therefore, has been to determine the relationship between contrast threshold elevation and visual field loss in corresponding regions of the peripheral visual field in glaucoma patients. METHODS: Contrast thresholds were measured in arcuate regions of the superior, inferior, nasal and temporal visual field in response to laser interference fringes presented in the Maxwellian view. The display consisted of vertical green stationary laser interference fringes of spatial frequency 1.0 c deg(-1 )which appeared in a rotatable viewing area in the form of a truncated quadrant extending from 10 to 20° from fixation which was marked with a central fixation light. Results were obtained from 36 normal control subjects in order to provide a normal reference for 21 glaucoma patients and 5 OHT (ocular hypertensive) patients for whom full clinical data, including Friedmann visual fields, had been obtained. RESULTS: Abnormally high contrast thresholds were identified in 20 out of 21 glaucoma patients and in 2 out of 5 OHT patients when compared with the 95% upper prediction limit for normal values from one eye of the 36 normal age-matched control subjects. Additionally, inter-ocular differences in contrast threshold were also abnormally high in 18 out of 20 glaucoma patients who had vision in both eyes compared with the 95% upper prediction limit. Correspondence between abnormally high contrast thresholds and visual field loss in the truncated quadrants was significant in 5 patients, borderline in 4 patients and absent in 9 patients. CONCLUSION: While the glaucoma patients tested in our study invariably had abnormally high contrast thresholds in one or more of the truncated quadrants in at least one eye, reasonable correspondence with the location of the visual field loss only occurred in half the patients studied. Hence, while contrast threshold elevations are indicative of glaucomatous damage to vision, they are providing a different assessment of visual function from conventional visual field tests