Theory of enhanced dynamical photo-thermal bi-stability effects in cuprous oxide/organic hybrid heterostructure

We theoretically demonstrate the formation of multiple bi-stability regions in the temperature pattern on the interface between a cuprous oxide quantum well and DCM2:CA:PS organic compound. The Frenkel molecular exciton of the DCM2 is brought into resonance with the $1S$ quadrupole Wannier-Mott exciton in the cuprous oxide by "solvatochromism" with CA. The resulting hybrid is thermalized with surrounding helium bath. This leads to strongly non-linear temperature dependence of the laser field detuning from the quadrupole exciton energy band which is associated with the temperature induced red shift of the Wannier exciton energy. Numerical up and down-scan for the detuning reveals hysteresis-like temperature distribution. The obtained \emph{multiple} bi-stability regions are at least three orders of magnitude bigger ($meV$) than the experimentally observed bi-stability in bulk cuprous oxide ($\mu eV$). The effective absorption curve exhibits highly asymmetrical behavior for the Frenkel-like (above the $1S$ energy) and Wannier-like (below the $1S$ energy) branches of the hybrid.Comment: 6 pages, 7 Figure

Properties of odd nuclei and the impact of time-odd mean fields: A systematic Skyrme-Hartree-Fock analysis

We present a systematic analysis of the description of odd nuclei by the Skyrme-Hartree-Fock approach augmented with pairing in BCS approximation and blocking of the odd nucleon. Current and spin densities in the Skyrme functional produce time-odd mean fields (TOMF) for odd nuclei. Their effect on basic properties (binding energies, odd-even staggering, separation energies and spectra) is investigated for the three Skyrme parameterizations SkI3, SLy6, and SV-bas. About 1300 spherical and axially-deformed odd nuclei with 16 < Z < 92 are considered. The calculations demonstrate that the TOMF effect is generally small, although not fully negligible. The influence of the Skyrme parameterization and the consistency of the calculations are much more important. With a proper choice of the parameterization, a good description of binding energies and their differences is obtained, comparable to that for even nuclei. The description of low-energy excitation spectra of odd nuclei is of varying quality depending on the nucleus

Cildb: a knowledgebase for centrosomes and cilia

Ciliopathies, pleiotropic diseases provoked by defects in the structure or function of cilia or flagella, reflect the multiple roles of cilia during development, in stem cells, in somatic organs and germ cells. High throughput studies have revealed several hundred proteins that are involved in the composition, function or biogenesis of cilia. The corresponding genes are potential candidates for orphan ciliopathies. To study ciliary genes, model organisms are used in which particular questions on motility, sensory or developmental functions can be approached by genetics. In the course of high throughput studies of cilia in Paramecium tetraurelia, we were confronted with the problem of comparing our results with those obtained in other model organisms. We therefore developed a novel knowledgebase, Cildb, that integrates ciliary data from heterogeneous sources. Cildb links orthology relationships among 18 species to high throughput ciliary studies, and to OMIM data on human hereditary diseases. The web interface of Cildb comprises three tools, BioMart for complex queries, BLAST for sequence homology searches and GBrowse for browsing the human genome in relation to OMIM information for human diseases. Cildb can be used for interspecies comparisons, building candidate ciliary proteomes in any species, or identifying candidate ciliopathy genes

Time-based and event-based prospective memory in autism spectrum disorder: The roles of executive function, theory of mind, and time-estimation

Prospective memory (remembering to carry out an action in the future) has been studied relatively little in ASD. We explored time-based (carry out an action at a pre-specified time) and event-based (carry out an action upon the occurrence of a pre-specified event) prospective memory, as well as possible cognitive correlates, among 21 intellectually high-functioning children with ASD, and 21 age- and IQ-matched neurotypical comparison children. We found impaired time-based, but undiminished event-based, prospective memory among children with ASD. In the ASD group, time-based prospective memory performance was associated significantly with diminished theory of mind, but not with diminished cognitive flexibility. There was no evidence that time-estimation ability contributed to time-based prospective memory impairment in ASD