600 research outputs found

    Petroleum generation and migration in the Cambro-Ordovician Laurentian margin succession of NW Scotland

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    NERC are thanked for continued funding of the Argon Isotope Facility, which is housed at SUERC. We are grateful to B. Fulton, J. Johnston and C. Taylor for skilled technical help. DM was in receipt of a NERC PhD studentship. A.G. Leslie and H. Volk provided critical comments that helped to improve the manuscript.Peer reviewedPublisher PD

    Metalliferous Biosignatures for Deep Subsurface Microbial Activity

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    Acknowledgments We thank the British Geological Survey (BGS) for the provision of samples and the Science & Technology Facilities Council (STFC) grant (ST/L001233/1) for PhD funding which aided this project. Research on selenium in reduction spheroids was also supported by NERC grants (NE/L001764/1 and NE/ M010953/1). The University of Aberdeen Raman facility was funded by the BBSRC. We also thank John Still for invaluable technical assistance.Peer reviewedPublisher PD

    The cAMP sensors, EPAC1 and EPAC2, display distinct subcellular distributions despite sharing a common nuclear pore localisation signal

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    We have identified a conserved nuclear pore localisation signal (NPLS; amino acids 764–838 of EPAC1) in the catalytic domains of the cAMP-sensors, EPAC1 and EPAC2A. Consequently, EPAC1 is mainly localised to the nuclear pore complex in HEK293T cells where it becomes activated following stimulation with cAMP. In contrast, structural models indicate that the cAMP-binding domain of EPAC2A (CNBD1) blocks access to the conserved NPLS in EPAC2A, reducing its ability to interact with nuclear binding sites. Consequently, a naturally occurring EPAC2 isoform, EPAC2B, which lacks CNBD1 is enriched in nuclear fractions, similar to EPAC1. Structural differences in EPAC isoforms may therefore determine their intracellular location and their response to elevations in intracellular cAMP

    Geochemistry and origin of organic-rich sediment veins in fractured granitic basement, Helmsdale, Sutherlandshire, UK

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    Acknowledgements MB is in receipt of a PhD studentship from the Petroleum Technology Development Fund of Nigeria. LB is supported by NERC grant NE/M010953/1. C. Taylor, W. Ritchie and J. Johnston provided skilled technical support. Sulphur isotope measurements were made at SUERC. The manuscript benefitted substantially from the careful reviews of A.G. Leslie and an anonymous referee.Peer reviewedPublisher PD

    Raman spectroscopy of shocked gypsum from a meteorite impact crater

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    Acknowledgements This work was funded by STFC grant ST/L001233/1. The University of Aberdeen Raman facility was funded by the BBSRC grant BBC5125101. Thanks to Jo Duncan for XRD assistance.Peer reviewedPublisher PD

    Learning from Civilia. Critical heterodoxies, historiography and urban design

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    Desde su primera publicación en 1971 como número especial de The Architectural Review, Civilia, The End of Suburban Man ha permanecido como un documento anómalo dentro de la historia de la teoría y la crítica arquitectónica. Profusamente ilustrado con collages hechos a partir de cientos de fotografías de edificios publicados en las páginas de la revista, el libro describía con un lenguaje cercano al manifiesto y en gran detalle una ficticia new town inglesa construida en una cantera abandonada. Situada en un difuso terrain vague entre ficción, sátira y propuesta genuina, Civilia era tanto una crítica al urbanismo inglés de posguerra y a las propuestas urbanas de la modernidad en general como una vívida ilustración del concepto de townscape que la revista llevaba promocionando varias décadas. “Learning from Civilia” ofrece una revisión crítica del contenido del libro, las circunstancias de su confección y su recepción, introduciendo finalmente The Civilia Project, una iniciativa de la Universidad de Newcastle que, integrando investigación y docencia, propone reexaminar Civilia no solo por su interés historiográfico, sino por su valor como herramienta de proyecto y por la relevancia que su discurso mantiene hoy en día, más aún, si cabe, en relación con el planeamiento urbano.Since its first publication in 1971 as a special issue of The Architectural Review, Civilia, The End of Suburban Man has remained an anomalous document within the history of Architectural Theory and Criticism. Profusely illustrated with collages made from hundreds of photographs of buildings published in the pages of the magazine, the book described, in great detail and with a language close to that of the manifesto, a fictional English New Town built in an abandoned quarry. Located in a diffuse terrain vague between fiction, satire and true proposal, Civilia was both a critique of post-war English urbanism and the urban proposals of modernity in general, standing as a vivid illustration of the concept of Townscape that the magazine had been promoting for several decades. ‘Learning from Civilia’ offers a critical review of the content of the book, the circumstances of its creation and its reception, and introduces The Civilia Project. An initiative of the University of Newcastle, The Civilia Project integrates research and teaching, and proposes a reexamination of Civilia not only due to its historiographic significance, but also because of its value as a design tool and for the relevance that its discourse maintains today, especially, in relation to urban planning

    Enhanced microbial activity in carbon-rich pillow lavas, Ordovician, Great Britain and Ireland

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    Date of acceptance: 09/07/2015 ACKNOWLEDGEMENTS A. Sandison and C. Taylor provided skilled technical support. Boyce is funded by Natural Environment Research Council (NERC) support of the Isotope Community Support Facility at the Scottish Universities Environmental Research Centre. NERC supported the project through facility grant IP-1235- 0511. The Raman spectroscopy facility at the University of Aberdeen is funded by the Biotechnology and Biological Sciences Research Council. We are grateful to M. Feely, G. Purvis, and an anonymous reviewer for helpful criticism.Peer reviewedPostprin
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