237 research outputs found
LEIR electron cooler status
The electron cooler for LEIR is the first of a new generation of coolers being commissioned for fast phase space cooling of ion beams in storage rings. It is a stateof- the-art cooler incorporating all the recent developments in electron cooling technology (adiabatic expansion, electrostatic bend, variable density electron beam) and is designed to deliver up to 600 mA of electron current for the cooling and stacking of Pb54+ ions in the frame of the ions for LHC project. In this paper we present our experience with the commissioning of the new device as well as the first results of ion beam cooling with a high-intensity variable-density electron beam
Ambient betatron motion and its excitation by ghost lines in Tevatron
Transverse betatron motion of the Tevatron proton beam is measured and
analyzed. It is shown that the motion is coherent and excited by external
sources of unknown origins. Observations of the time varying ghost lines in the
betatron spectra are reported.Comment: 9 p
Use of high throughput sequencing to observe genome dynamics at a single cell level
With the development of high throughput sequencing technology, it becomes
possible to directly analyze mutation distribution in a genome-wide fashion,
dissociating mutation rate measurements from the traditional underlying
assumptions. Here, we sequenced several genomes of Escherichia coli from
colonies obtained after chemical mutagenesis and observed a strikingly
nonrandom distribution of the induced mutations. These include long stretches
of exclusively G to A or C to T transitions along the genome and orders of
magnitude intra- and inter-genomic differences in mutation density. Whereas
most of these observations can be explained by the known features of enzymatic
processes, the others could reflect stochasticity in the molecular processes at
the single-cell level. Our results demonstrate how analysis of the molecular
records left in the genomes of the descendants of an individual mutagenized
cell allows for genome-scale observations of fixation and segregation of
mutations, as well as recombination events, in the single genome of their
progenitor.Comment: 22 pages, 9 figures (including 5 supplementary), one tabl
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