1,170 research outputs found
Word frequency, predictability, and return-sweep saccades: Towards the modeling of eye movements during paragraph reading.
Models of eye movement control during reading focus on the reading of single lines of text. Within these models, word frequency and predictability are important input variables which influence fixation probabilities and durations. However, a comprehensive model of eye movement control will have to account for readers' eye movements across multiline texts. Line-initial words are unlike those presented midline; they are routinely unavailable for parafoveal preprocessing. Therefore, it is unclear whether and how word frequency and predictability influence reading times on line-initial words. To address this, we present an analysis of the Provo Corpus (Luke & Christianson, 2018) followed by a novel eye-movement experiment. We conclude that word frequency and predictability impact single-fixation and gaze durations on line-initial words. We also observed that return-sweep error (undersweep-fixations) may, among several other possibilities, allow for parafoveal processing of line-initial words prior to their direct fixation. Implications for models of eye movement control during reading are discussed. (PsycINFO Database Record (c) 2019 APA, all rights reserved)
Denominator identities for finite-dimensional Lie superalgebras and Howe duality for compact dual pairs
We provide formulas for the denominator and superdenominator of a basic
classical type Lie superalgebra for any set of positive roots. We establish a
connection between certain sets of positive roots and the theory of reductive
dual pairs of real Lie groups. As an application of our formulas, we recover
the Theta correspondence for compact dual pairs. Along the way we give an
explicit description of the real forms of basic classical type Lie
superalgebras.Comment: Latex, 75 pages. Minor corrections. Final version, to appear in the
Japanese Journal of Mathematic
Current Helicity and Twist as Two Indicators of The Mirror Asymmetry of solar Magnetic Fields
A comparison between the two tracers of magnetic field mirror asymmetry in
solar active regions, twist and current helicity, is presented. It is shown
that for individual active regions these tracers do not possess visible
similarity while averaging by time over the solar cycle, or by latitude,
reveals similarities in their behaviour. The main property of the dataset is
anti-symmetry over the solar equator. Considering the evolution of helical
properties over the solar cycle we find signatures of a possible sign change at
the beginning of the cycle, though more systematic observational data are
required for a definite confirmation. We discuss the role of both tracers in
the context of the solar dynamo theory.Comment: 14 pages, 6 figure
Development and validation of a NanoString BASE47 bladder cancer gene classifier
Background Recent molecular characterization of urothelial cancer (UC) has suggested potential pathways in which to direct treatment, leading to a host of targeted therapies in development for UC. In parallel, gene expression profiling has demonstrated that high-grade UC is a heterogeneous disease. Prognostic basal-like and luminal-like subtypes have been identified and an accurate transcriptome BASE47 classifier has been developed. However, these phenotypes cannot be broadly investigated due to the lack of a clinically viable diagnostic assay. We sought to develop and evaluate a diagnostic classifier of UC subtype with the goal of accurate classification from clinically available specimens. Methods Tumor samples from 52 patients with high-grade UC were profiled for BASE47 genes concurrently by RNAseq as well as NanoString. After design and technical validation of a BASE47 NanoString probeset, results from the RNAseq and NanoString were used to translate diagnostic criteria to the Nanostring platform. Evaluation of repeatability and accuracy was performed to derive a final Nanostring based classifier. Diagnostic classification resulting from the NanoString BASE47 classifier was validated on an independent dataset (n = 30). The training and validation datasets accurately classified 87% and 93% of samples, respectively. Results Here we have derived a NanoString-platform BASE47 classifier that accurately predicts basal-like and luminal-like subtypes in high grade urothelial cancer. We have further validated our new NanoString BASE47 classifier on an independent dataset and confirmed high accuracy when compared with our original Transcriptome BASE47 classifier. Conclusions The NanoString BASE47 classifier provides a faster turnaround time, a lower cost per sample to process, and maintains the accuracy of the original subtype classifier for better clinical implementation
Modelling and Interpreting The Effects of Spatial Resolution on Solar Magnetic Field Maps
Different methods for simulating the effects of spatial resolution on
magnetic field maps are compared, including those commonly used for
inter-instrument comparisons. The investigation first uses synthetic data, and
the results are confirmed with {\it Hinode}/SpectroPolarimeter data. Four
methods are examined, one which manipulates the Stokes spectra to simulate
spatial-resolution degradation, and three "post-facto" methods where the
magnetic field maps are manipulated directly. Throughout, statistical
comparisons of the degraded maps with the originals serve to quantify the
outcomes. Overall, we find that areas with inferred magnetic fill fractions
close to unity may be insensitive to optical spatial resolution; areas of
sub-unity fill fractions are very sensitive. Trends with worsening spatial
resolution can include increased average field strength, lower total flux, and
a field vector oriented closer to the line of sight. Further-derived quantities
such as vertical current density show variations even in areas of high average
magnetic fill-fraction. In short, unresolved maps fail to represent the
distribution of the underlying unresolved fields, and the "post-facto" methods
generally do not reproduce the effects of a smaller telescope aperture. It is
argued that selecting a method in order to reconcile disparate spatial
resolution effects should depend on the goal, as one method may better preserve
the field distribution, while another can reproduce spatial resolution
degradation. The results presented should help direct future inter-instrument
comparisons.Comment: Accepted for publication in Solar Physics. The final publication
(including full-resolution figures) will be available at
http://www.springerlink.co
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Industrial demand side management status report: Synopsis
Industrial demand side management (DSM) programs, though not as developed or widely implemented as residential and commercial programs, hold the promise of significant energy savings-savings that will benefit industrial firms, utilities and the environment. This paper is a synopsis of a larger research report, Industrial Demand Side Management. A Status Report, prepared for the US Department of Energy. The report provides an overview of and rationale for DSM programs. Benefits and barriers are described, and data from the Manufacturing Energy Consumption Survey are used to estimate potential electricity savings from industrial energy efficiency measures. Overcoming difficulties to effective program implementation is worthwhile, since rough estimates indicate a substantial potential for electricity savings. The report categorizes types of DSM programs, presents several examples of each type, and explores elements of successful programs. Two in-depth case studies (of Boise Cascade and of Eli Lilly and Company) illustrate two types of effective DSM programs. Interviews with staff from state public utility commissions indicate the current thinking about the status and future of industrial DSM programs. Finally, the research report also includes a comprehensive bibliography, a description of technical assistance programs, and an example of a methodology for evaluating potential or actual savings from projects
Helioseismology of Sunspots: A Case Study of NOAA Region 9787
Various methods of helioseismology are used to study the subsurface
properties of the sunspot in NOAA Active Region 9787. This sunspot was chosen
because it is axisymmetric, shows little evolution during 20-28 January 2002,
and was observed continuously by the MDI/SOHO instrument. (...) Wave travel
times and mode frequencies are affected by the sunspot. In most cases, wave
packets that propagate through the sunspot have reduced travel times. At short
travel distances, however, the sign of the travel-time shifts appears to depend
sensitively on how the data are processed and, in particular, on filtering in
frequency-wavenumber space. We carry out two linear inversions for wave speed:
one using travel-times and phase-speed filters and the other one using mode
frequencies from ring analysis. These two inversions give subsurface wave-speed
profiles with opposite signs and different amplitudes. (...) From this study of
AR9787, we conclude that we are currently unable to provide a unified
description of the subsurface structure and dynamics of the sunspot.Comment: 28 pages, 18 figure
Extension of Earth-Moon libration point orbits with solar sail propulsion
This paper presents families of libration point orbits in the Earth-Moon system that originate from complementing the classical circular restricted three-body problem with a solar sail. Through the use of a differential correction scheme in combination with a continuation on the solar sail induced acceleration, families of Lyapunov, halo, vertical Lyapunov, Earth-centred, and distant retrograde orbits are created. As the solar sail circular restricted three-body problem is non-autonomous, a constraint defined within the differential correction scheme ensures that all orbits are periodic with the Sun’s motion around the Earth-Moon system. The continuation method then starts from a classical libration point orbit with a suitable period and increases the solar sail acceleration magnitude to obtain families of orbits that are parametrised by this acceleration. Furthermore, different solar sail steering laws are considered (both in-plane and out-of-plane, and either fixed in the synodic frame or fixed with respect to the direction of sunlight), adding to the wealth of families of solar sail enabled libration point orbits presented. Finally, the linear stability properties of the generated orbits are investigated to assess the need for active orbital control. It is shown that the solar sail induced acceleration can have a positive effect on the stability of some orbit families, especially those at the L2 point, but that it most often (further) destabilises the orbit. Active control will therefore be needed to ensure long-term survivability of these orbits
Red Queen Coevolution on Fitness Landscapes
Species do not merely evolve, they also coevolve with other organisms.
Coevolution is a major force driving interacting species to continuously evolve
ex- ploring their fitness landscapes. Coevolution involves the coupling of
species fit- ness landscapes, linking species genetic changes with their
inter-specific ecological interactions. Here we first introduce the Red Queen
hypothesis of evolution com- menting on some theoretical aspects and empirical
evidences. As an introduction to the fitness landscape concept, we review key
issues on evolution on simple and rugged fitness landscapes. Then we present
key modeling examples of coevolution on different fitness landscapes at
different scales, from RNA viruses to complex ecosystems and macroevolution.Comment: 40 pages, 12 figures. To appear in "Recent Advances in the Theory and
Application of Fitness Landscapes" (H. Richter and A. Engelbrecht, eds.).
Springer Series in Emergence, Complexity, and Computation, 201
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