422 research outputs found
Annotation Studio: Multimedia Annotation for Students
Annotation Studio is a web-based annotation application that integrates a powerful set of textual interpretation tools behind an interface that makes using those tools intuitive for undergraduates. Building on studentsâ new media literacies, this Open-source application develops traditional humanistic skills including close reading, textual analysis, persuasive writing, and critical thinking. Initial features of the Annotation Studio prototype, supported by an NEH Start-Up Grant, include aligned multi-media annotation of written texts, user-defined sharing of annotations, and grouping of annotation by self-defined tags to support interpretation and argument development. The fully developed application will support annotation of image, video and audio documents; annotation visualization; export of texts with annotations; and a media repository. We will also identify best practices among faculty using Annotation Studio in a broad range of humanities classes across the country
Annotation Studio: multimedia text annotation for students
Annotation Studio will be a web-based application that actively engages students in interpreting literary texts and other humanities documents. While strengthening students' new media literacies, this open source web application will develop traditional humanistic skills including close reading, textual analysis, persuasive writing, and critical thinking. Initial features will include: 1) easy-to-use annotation tools that facilitate linking and comparing primary texts with multi-media source, variation, and adaptation documents; 2) sharable collections of multimedia materials prepared by faculty and student users; 3) multiple filtering and display mechanisms for texts, written annotations, and multimedia annotations; 4) collaboration functionality; and 5) multimedia composition tools. Products of the start-up phase will include a working prototype, feedback from students and instructors, and a white paper summarizing lessons learned
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Energy Organizational Planning
As the Seneca Nation of Indians (SNI) continues to refine and finalize its Strategic Energy Plan, it became necessary to insure that a sustainable organization structure was developed through which the energy program and its initiatives could be nurtured and managed. To that end, SNI undertook a study to thoroughly evaluate the existing organizational structures and assess the requisite changes and/or additions to that framework that would complement the mission of the Strategic Plan. The goal of this study was to analyze, work with staff and leadership and recommend the most effective plan for the development of an organizational framework within which the Seneca could more effectively exercise energy sovereignty â control and manage their natural resource assets â i.e. develop its own energy resources, meet the current and projected energy needs of their community, and âsit at the tableâ with other regional energy providers to deal with issues on a peer-to-peer basis
Identification of C-C Chemokine Receptor 1 (CCR1) as the Monocyte Hemofiltrate C-C Chemokine (HCC)-1 Receptor
Hemofiltrate C-C chemokine (HCC)-1 is a recently cloned C-C chemokine that is structurally similar to macrophage inflammatory protein (MIP)-1α. Unlike most chemokines, it is constitutively secreted by tissues and is present at high concentrations in normal human plasma. Also atypical for chemokines, HCC-1 is reported not to be chemotactic for leukocytes. In this paper, we have investigated the chemokine receptor usage and downstream signaling pathways of HCC-1. Cross-desensitization experiments using THP-1 cells suggested that HCC-1 and MIP-1α activated the same receptor. Experiments using a panel of cloned chemokine receptors revealed that HCC-1 specifically activated C-C chemokine receptor (CCR)1, but not closely related receptors, including CCR5. HCC-1 competed with MIP-1α for binding to CCR1-transfected cells, but with a markedly reduced affinity (IC50 = 93 nM versus 1.3 nM for MIP-1α). Similarly, HCC-1 was less potent than MIP-1α in inducing inhibition of adenylyl cyclase in CCR1-transfected cells. HCC-1 induced chemotaxis of freshly isolated human monocytes, THP-1 cells, and CCR1-transfected cells, and the optimal concentration for cell migration (100 nM) was âŒ100-fold lower than that of MIP-1α (1 nM). These data demonstrate that HCC-1 is a chemoattractant and identify CCR1 as a functional HCC-1 receptor on human monocytes
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Influence de la taille et dea la saison de pĂȘche sur les qualitĂ©s organoleptiques des palourdes de l'atlantique (spisula solidissima) et la volontĂ© Ă payer du consommateur
Dans un marchĂ© de libre concurrence, certains paramĂštres tels que la saison de pĂȘche et la taille des produits halieutiques ont une trĂšs grande importance sur la fixation des prix et la volontĂ© Ă payer du consommateur. Afin de valider ces donnĂ©es, des Ă©chantillons de palourdes de l'Atlantique (Spisula solidissima), pĂȘchĂ©s dans la zone 4T du Fleuve Saint-Laurent durant trois pĂ©riodes diffĂ©rentes de l'annĂ©e, ont Ă©tĂ© repartis en quatre classes de taille et soumis aprĂšs cuisson aux membres d'un Jury semi - entraĂźnĂ© pour des tests d'Ă©valuation organoleptique. La tendretĂ© et la saveur des palourdes de taille petite et moyenne ont Ă©tĂ© prĂ©fĂ©rĂ©es a celle de taille plus grande. De plus les Ă©chantillons d'Ă©tĂ© et d'automne sont meilleurs au goĂ»t que ceux de printemps. Alors que la pĂ©riode de pĂȘche et la taille des individus n'ont pas d'influence significative sur la composition proximale (teneur en humiditĂ©, protĂ©ine et lipides), la composition en acides aminĂ©s libres responsables de la saveur des produits marins varie de façon significative entre les parties anatomiques de la palourde. Quant a la volontĂ© a payer du consommateur, elle est beaucoup moins forte pour les palourdes de printemps et celles de plus grande taille.Keywords: Clams, Size, Demand, Willingness-to-pay, Consumers, Flavou
Le Forum, Vol. 40 No. 2
https://digitalcommons.library.umaine.edu/francoamericain_forum/1087/thumbnail.jp
Le FORUM, Vol. 35 No. 2
https://digitalcommons.library.umaine.edu/francoamericain_forum/1030/thumbnail.jp
Are chest compressions safe for the patient reconstructed with sternal plates? Evaluating the safety of cardiopulmonary resuscitation using a human cadaveric model
<p>Abstract</p> <p>Background</p> <p>Plate and screw fixation is a recent addition to the sternal wound treatment armamentarium. Patients undergoing cardiac and major vascular surgery have a higher risk of postoperative arrest than other elective patients. Those who undergo sternotomy for either cardiac or major vascular procedures are at a higher risk of postoperative arrest. Sternal plate design allows quick access to the mediastinum facilitating open cardiac massage, but chest compressions are the mainstay of re-establishing cardiac output in the event of arrest. The response of sternal plates and the chest wall to compressions when plated has not been studied. The safety of performing this maneuver is unknown. This study intends to demonstrate compressions are safe after sternal plating.</p> <p>Methods</p> <p>We investigated the effect of chest compressions on the plated sternum using a human cadaveric model. Cadavers were plated, an arrest was simulated, and an experienced physician performed a simulated resuscitation. Intrathoracic pressure was monitored throughout to ensure the plates encountered an appropriate degree of force. The hardware and viscera were evaluated for failure and trauma respectively.</p> <p>Results</p> <p>No hardware failure or obvious visceral trauma was observed. Rib fractures beyond the boundaries of the plates were noted but the incidence was comparable to control and to the fracture incidence after resuscitation previously cited in the literature.</p> <p>Conclusions</p> <p>From this work we believe chest compressions are safe for the patient with sternal plates when proper plating technique is used. We advocate the use of this life-saving maneuver as part of an ACLS resuscitation in the event of an arrest for rapidly re-establishing circulation.</p
Le Forum, Vol. 40 No. 3
https://digitalcommons.library.umaine.edu/francoamericain_forum/1088/thumbnail.jp
F.A.R.O.G. FORUM, Vol. 2 No. 11
https://digitalcommons.library.umaine.edu/francoamericain_forum/1010/thumbnail.jp
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