Recreational reading : a case study of recreational reading habits of some primary school pupils and the role of the teacher-librarian in intervention strategies

Bibliography: leaves 101-107.An interest in the topic of recreational reading was prompted by the observations and experience of the researcher. The study that followed was intended to confirm or refute the theory of the decline of reading. A perceived decline in reading has concerned teachers and librarians and strategies have been devised to reverse this trend. The strategies used by the researcher were adopted and adapted to meet the pupils' recreational reading needs. Methods that were likely to reverse the trend in the decline of reading were used with the expectation that the reading programme would affect reading behaviour and that pupils would be encouraged to read for pleasure. The case study method which included both a questionnaire and discussion with the pupils was used. Studies of this kind are scarce and out-dated, but this investigation has been of value to the pupils, teachers and the researcher as teacher-librarian, for all have benefitted from the stimulating and interesting input from the interventive strategies. A number of the results proved to be unforeseen, such as a decline in recreational reading generally throughout the group, and also the children's perception of the short amount of time they spend viewing television. These were contrary to the findings of all previous studies and should be treated with circumspection. The role of the school library and the teacher-librarian are essential in schools today as they are of great benefit to the whole school community. The study has proved without a doubt that availability of reading resources and guidance to the pupils in making stimulating and interesting choices should be the aim of all concerned with children's reading so that their needs can be met and the reading habit fostered

EMERGING COMMERCIALIZATION OF ELEARNING

Technology innovation drives the current elearning market but recent events suggest this model is failing economically. Alternately a market driven by learners, rather than technology is more likely to be competitive and profitable. We examine elearning within the context of a developing academic and skills educational market to pose the question: do existing suppliers (old and new) meet the new market needs? Using Porter’s competitive environment model to analyse the current market position of universities, publishers and other education providers within the Reeves-Ellington Producer/Consumer Framework. The authors examine what an elearning customer research model might look like by using a customer -Reeves- Ellington’s supplier within the Kaplan and Norton Balanced Scorecard approach and the Palmer Learning Design Framewor

Plants and trees of syrio-palestine: cultivation and uses

No abstract availableOLD TESTAMENT and ANCIENT NEMA (BIBLICAL ARCHAEOLOGY

Targeting SOCS proteins to control JAK-STAT signalling in disease

No abstract available

Do T2DM and Hyperglycaemia Affect the Expression Levels of the Regulating Enzymes of Cellular O-GlcNAcylation in Human Saphenous Vein Smooth Muscle Cells?

Protein O-GlcNAcylation, a dynamic and reversible glucose-dependent post-translational modification of serine and threonine residues on target proteins, has been proposed to promote vascular smooth muscle cell proliferation and migration events implicated in vein graft failure (VGF). Therefore, targeting the enzymes (glutamine fructose-6P amidotransferase (GFAT), O-GlcNAc transferase (OGT), and O-GlcNAcase (OGA)) that regulate cellular O-GlcNAcylation could offer therapeutic options to reduce neointimal hyperplasia and venous stenosis responsible for VGF. However, it is unclear how type 2 diabetes mellitus (T2DM) and hyperglycaemia affect the expression of these enzymes in human saphenous vein smooth muscle cells (HSVSMCs), a key cell type involved in the vascular dysfunction responsible for saphenous VGF. Therefore, our aim was to assess whether T2DM and hyperglycaemia affect GFAT, OGT, and OGA expression levels in HSVSMCs in vitro. Expression levels of GFAT, OGT, and OGA were determined in low-passage HSVSMCs from T2DM and non-T2DM patients, and in HSVSMCs treated for 48 h with hyperglycaemic (10 mM and 25 mM) glucose concentrations, by quantitative immunoblotting. Expression levels of OGT, OGA, and GFAT were not significantly different in HSVSMC lysates from T2DM patients versus non-T2DM controls. In addition, treatment with high glucose concentrations (10 mM and 25 mM) had no significant effect on the protein levels of these enzymes in HSVSMC lysates. From our findings, T2DM and hyperglycaemia do not significantly impact the expression levels of the O-GlcNAcylation-regulating enzymes OGT, OGA, and GFAT in HSVSMCs. This study provides a foundation for future studies to assess the role of O-GlcNAcylation on VGF in T2DM

Insulin and insulin-like growth factor-I responsiveness and signalling mechanisms in C2C12 satellite cells: effect of differentiation and fusion

AbstractIn proliferating C2C12 myoblasts, serum and physiological concentrations of insulin and IGF-I stimulated protein synthesis and RNA accretion. After fusion, the multinucleated myotubes remained responsive to serum but not to insulin or IGF-I, even though both insulin and type-1 IGF receptor mRNAs increased in abundance. Protein synthetic responses to insulin and IGF-I in myoblasts were not inhibited by dexamethasone, ibuprofen or Ro-31-8220, thus phospholipase A2, cyclo-oxygenase and protein kinase C did not appear to be involved in the signalling mechanisms. Neither apparently were polyphosphoinositide-specific phospholipase C or phospholipase D since neither hormone increased inositol phosphate, phosphatidic acid, choline or phosphatidylbutanol production. Only the phosphatidylinositol-3-kinase inhibitor, wortmannin, and the 70 kDa S6-kinase inhibitor, rapamycin, wholly or partially blocked the effects of insulin and IGF-I on protein synthesis. 2-deoxyglucose uptake remained responsive to insulin and IGF-I after fusion and was also inhibited by wortmannin. The results suggest that the loss of responsiveness after fusion is not due to loss of receptors, but to the uncoupling of a post-receptor pathway, occurring after the divergence of the glucose transport and protein synthesis signalling systems, and that, if wortmannin acts at a single site, this is prior to that point of divergence

The Infrared Spectrum of Uranium Hollow Cathode Lamps from 850 nm to 4000 nm: Wavenumbers and Line Identifications from Fourier Transform Spectra

We provide new measurements of wavenumbers and line identifications of 10 100 UI and UII near-infrared (NIR) emission lines between 2500 cm-1 and 12 000 cm-1 (4000 nm to 850 nm) using archival FTS spectra from the National Solar Observatory (NSO). This line list includes isolated uranium lines in the Y, J, H, K, and L bands (0.9 {\mu}m to 1.1 {\mu}m, 1.2 {\mu}m to 1.35 {\mu}m, 1.5 {\mu}m to 1.65 {\mu}m, 2.0 {\mu}m to 2.4 {\mu}m, and 3.0 {\mu}m to 4.0 {\mu}m, respectively), and provides six times as many calibration lines as thorium in the NIR spectral range. The line lists we provide enable inexpensive, commercially-available uranium hollow-cathode lamps to be used for high-precision wavelength calibration of existing and future high-resolution NIR spectrographs.Comment: 23 pages, 6 Figure

A High-Resolution Atlas of Uranium-Neon in the H Band

We present a high-resolution (R ~ 50 000) atlas of a uranium-neon (U/Ne) hollow-cathode spectrum in the H-band (1454 nm to 1638 nm) for the calibration of near-infrared spectrographs. We obtained this U/Ne spectrum simultaneously with a laser-frequency comb spectrum, which we used to provide a first-order calibration to the U/Ne spectrum. We then calibrated the U/Ne spectrum using the recently-published uranium line list of Redman et al. (2011), which is derived from high-resolution Fourier transform spectrometer measurements. These two independent calibrations allowed us to easily identify emission lines in the hollow cathode lamp that do not correspond to known (classified) lines of either uranium or neon, and to compare the achievable precision of each source. Our frequency comb precision was limited by modal noise and detector effects, while the U/Ne precision was limited primarily by the signal-to-noise ratio (S/N) of the observed emission lines and our ability to model blended lines. The standard deviation in the dispersion solution residuals from the S/N-limited U/Ne hollow cathode lamp were 50% larger than the standard deviation of the dispersion solution residuals from the modal-noise-limited laser frequency comb. We advocate the use of U/Ne lamps for precision calibration of near-infrared spectrographs, and this H-band atlas makes these lamps significantly easier to use for wavelength calibration.Comment: 23 pages, 7 figures, submitted and accepted in ApJSS. Online-only material to be published online by ApJS

Anticipated regret to increase uptake of colorectal cancer screening (ARTICS):a randomised controlled trial

Objective. Screening is key to early detection of colorectal cancer. Our aim was to determine whether a simple anticipated regret (AR) intervention could increase colorectal cancer screening uptake. Methods. We conducted a randomised controlled trial of a simple, questionnaire-based AR intervention, delivered alongside existing pre-notification letters. 60,000 adults aged 50-74 from the Scottish National Screening programme were randomised to: 1) no questionnaire (control), 2) Health Locus of Control questionnaire (HLOC) or 3) HLOC plus anticipated regret questionnaire (AR). Primary outcome was guaiac Faecal Occult Blood Test (FOBT) return. Secondary outcomes included intention to return test kit and perceived disgust (ICK). Results. 59,366 people were analysed as allocated (Intentionto- treat (ITT)); there were no overall differences between treatment groups on FOBT uptake (control: 57.3%, HLOC: 56.9%, AR: 57.4%). 13,645 (34.2%) people returned questionnaires. Analysis of the secondary questionnaire measures showed that AR had an indirect effect on FOBT uptake via intention, whilst ICK had a direct effect on FOBT uptake over and above intention. The effect of AR on FOBT uptake was also moderated by intention strength: for less than strong intenders only, uptake was 4.2% higher in the AR (84.6%) versus the HLOC group (80.4%) (95% CI for difference (2.0, 6.5)). Conclusion. The findings show that psychological concepts including anticipated regret and perceived disgust (ICK) are important factors in determining FOBT uptake. However, there was no simple effect of the AR intervention in the ITT. We conclude that exposure to AR in those with low intentions may be required to increase FOBT uptake. Current controlled trials: www.controlledtrials. com number: ISRCTN74986452